Enhancement of adenovirus infection and adenoviral vector-mediated gene delivery by bromodomain inhibitor JQ1

Applications of Virus Vector–Mediated Gene Therapy in China

(2018) Qiong Lin et al.   HUMAN GENE THERAPY

Gene therapy clinical trials worldwide to 2017: An update

(2018) Samantha L. Ginn et al.   JOURNAL OF GENE MEDICINE

Histone deacetylase inhibitor trichostatin A enhances the antitumor effect of the oncolytic adenovirus H101 on esophageal squamous cell carcinoma in vitro and in vivo

(2017) Junfen Ma et al.   Oncology Letters

P-TEFb goes viral

(2016) Justyna Zaborowska et al.   BIOESSAYS

The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous Proteins

(2016) Yasushi Taniguchi   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A core viral protein binds host nucleosomes to sequester immune danger signals

(2016) Daphne C. Avgousti et al.   NATURE

Cracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFb

(2016) Alexandre J. C. Quaresma et al.   NUCLEIC ACIDS RESEARCH

An Epigenetic Compound Library Screen Identifies BET Inhibitors That Promote HSV-1 and -2 Replication by Bridging P-TEFb to Viral Gene Promoters through BRD4

(2016) Ke Ren et al.   PLoS Pathogens

Methods and clinical development of adenovirus-vectored vaccines against mucosal pathogens

(2016) Sam Afkhami et al.   Molecular Therapy-Methods & Clinical Development

Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions

(2014) Michael Brand et al.   ACS Chemical Biology

Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection

(2014) Roberto Ferrari et al.   Cell Host & Microbe

Adenovirus Vectors for Gene Therapy, Vaccination and Cancer Gene Therapy

(2014) William Wold et al.   CURRENT GENE THERAPY

The importance of coagulation factors binding to adenovirus: historical perspectives and implications for gene delivery

(2014) Estrella Lopez-Gordo et al.   Expert Opinion on Drug Delivery

CDK9 inhibitor FIT-039 prevents replication of multiple DNA viruses

(2014) Makoto Yamamoto et al.   JOURNAL OF CLINICAL INVESTIGATION

Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation

(2014) Friederike Itzen et al.   NUCLEIC ACIDS RESEARCH

Characterization of molecular and cellular functions of the cyclin-dependent kinase CDK9 using a novel specific inhibitor

(2013) T K Albert et al.   BRITISH JOURNAL OF PHARMACOLOGY

Reactivation of latent HIV: do all roads go through P-TEFb?

(2013) Sona Budhiraja et al.   Future Virology

Recruitment of Brd4 to the Human Papillomavirus Type 16 DNA Replication Complex Is Essential for Replication of Viral DNA

(2013) X. Wang et al.   JOURNAL OF VIROLOGY

The Role of Chromatin in Adenoviral Vector Function

(2013) Carmen Wong et al.   Viruses-Basel

Reorganization of the host epigenome by a viral oncogene

(2012) R. Ferrari et al.   GENOME RESEARCH

Immune activation and antitumor response of ar-turmerone on P388D1 lymphoblast cell implanted tumors

(2012) DONGHEE KIM et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Replication-Uncoupled Histone Deposition during Adenovirus DNA Replication

(2012) T. Komatsu et al.   JOURNAL OF VIROLOGY

Signal-induced Brd4 release from chromatin is essential for its role transition from chromatin targeting to transcriptional regulation

(2011) Nanping Ai et al.   NUCLEIC ACIDS RESEARCH

The HDAC Inhibitor FK228 Enhances Adenoviral Transgene Expression by a Transduction-Independent Mechanism but Does Not Increase Adenovirus Replication

(2011) Angelika Danielsson et al.   PLoS One

Selective inhibition of BET bromodomains

(2010) Panagis Filippakopoulos et al.   NATURE

Cellular and viral chromatin proteins are positive factors in the regulation of adenovirus gene expression

(2010) Tetsuro Komatsu et al.   NUCLEIC ACIDS RESEARCH

Requirements for Receptor Engagement during Infection by Adenovirus Complexed with Blood Coagulation Factor X

(2010) Angela C. Bradshaw et al.   PLoS Pathogens

Host Cell Detection of Noncoding Stuffer DNA Contained in Helper-Dependent Adenovirus Vectors Leads to Epigenetic Repression of Transgene Expression

(2009) P. J. Ross et al.   JOURNAL OF VIROLOGY

Viral manipulation of the host epigenome for oncogenic transformation

(2009) Roberto Ferrari et al.   NATURE REVIEWS GENETICS