Targeting the polyadenylation factor EhCFIm25 with RNA aptamers controls survival in Entamoeba histolytica

Silencing the cleavage factor CFIm25 as a new strategy to control Entamoeba histolytica parasite

(2017) Juan David Ospina-Villa et al.   JOURNAL OF MICROBIOLOGY

Cleavage and polyadenylation: Ending the message expands gene regulation

(2017) Jonathan Neve et al.   RNA Biology

A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue

(2017) Ebere Sonoiki et al.   Nature Communications

Cleavage factor Im (CFIm) as a regulator of alternative polyadenylation

(2016) J. G. Hardy et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Aptamers as a promising approach for the control of parasitic diseases

(2016) Juan David Ospina-Villa et al.   Brazilian Journal of Infectious Diseases

A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes

(2016) Saima M. Sidik et al.   CELL

Amino acid residues Leu135 and Tyr236 are required for RNA binding activity of CFIm25 in Entamoeba histolytica

(2015) Juan David Ospina-Villa et al.   BIOCHIMIE

Transcriptional profile of processing machinery of 3′ end of mRNA in Trichomonas vaginalis

(2015) Miguel Ángel Del-Moral-Stevenel et al.   Genes & Genomics

NPDock: a web server for protein–nucleic acid docking

(2015) Irina Tuszynska et al.   NUCLEIC ACIDS RESEARCH

The isolation of an RNA aptamer targeting to p53 protein with single amino acid mutation

(2015) Liang Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of malaria parasite-infected red blood cell surface aptamers by inertial microfluidic SELEX (I-SELEX)

(2015) Christina M. Birch et al.   Scientific Reports

Aptamer-Based Detection of Disease Biomarkers in Mouse Models for Chagas Drug Discovery

(2015) Fernanda Fortes de Araujo et al.   PLoS Neglected Tropical Diseases

Molecular and Functional Characterization of ssDNA Aptamers that Specifically Bind Leishmania infantum PABP

(2015) Natalia Guerra-Pérez et al.   PLoS One

Proteomic analysis of Entamoeba histolytica in vivo assembled pre-mRNA splicing complexes

(2014) Jesús Valdés et al.   Journal of Proteomics

Proteomic profiling reveals that EhPC4 transcription factor induces cell migration through up-regulation of the 16-kDa actin-binding protein EhABP16 in Entamoeba histolytica

(2014) Olga Hernández de la Cruz et al.   Journal of Proteomics

Delineating the Structural Blueprint of the Pre-mRNA 3'-End Processing Machinery

(2014) K. Xiang et al.   MOLECULAR AND CELLULAR BIOLOGY

Cationic Surfactant-Based Colorimetric Detection of Plasmodium Lactate Dehydrogenase, a Biomarker for Malaria, Using the Specific DNA Aptamer

(2014) Seonghwan Lee et al.   PLoS One

Aptamer Based, Non-PCR, Non-Serological Detection of Chagas Disease Biomarkers in Trypanosoma cruzi Infected Mice

(2014) Rana Nagarkatti et al.   PLoS Neglected Tropical Diseases

The 25 kDa Subunit of Cleavage Factor Im Is a RNA-Binding Protein That Interacts with the Poly(A) Polymerase in Entamoeba histolytica

(2013) Marisol Pezet-Valdez et al.   PLoS One

DNA Aptamers Selectively Target Leishmania infantum H2A Protein

(2013) M. Elena Martín et al.   PLoS One

Structural basis for discriminatory recognition of Plasmodium lactate dehydrogenase by a DNA aptamer

(2013) Y.-W. Cheung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deciphering molecular mechanisms of mRNA metabolism in the deep-branching eukaryote Entamoeba histolytica

(2013) César López-Camarillo et al.   Wiley Interdisciplinary Reviews-RNA

Quantification of stochastic noise of splicing and polyadenylation in Entamoeba histolytica

(2012) Chung-Chau Hon et al.   NUCLEIC ACIDS RESEARCH

Development of an Aptamer-Based Concentration Method for the Detection of Trypanosoma cruzi in Blood

(2012) Rana Nagarkatti et al.   PLoS One

Structural basis of pre-mRNA recognition by the human cleavage factor Im complex

(2011) Heng Li et al.   CELL RESEARCH

Chimeric aptamers in cancer cell-targeted drug delivery

(2011) Jagat R. Kanwar et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Crystal Structure of a Human Cleavage Factor CFIm25/CFIm68/RNA Complex Provides an Insight into Poly(A) Site Recognition and RNA Looping

(2011) Qin Yang et al.   STRUCTURE

Tissue destruction and invasion by Entamoeba histolytica

(2011) Katherine S. Ralston et al.   TRENDS IN PARASITOLOGY

Approaches to characterizing Entamoeba histolytica transcriptional regulation

(2010) Richard J. Pearson et al.   CELLULAR MICROBIOLOGY

Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation

(2010) Sol Kim et al.   GENES TO CELLS

In Vitro Selection of Leishmania infantum H3-Binding ssDNA Aptamers

(2010) Edurne Ramos et al.   OLIGONUCLEOTIDES

Structural basis of UGUA recognition by the Nudix protein CFIm25 and implications for a regulatory role in mRNA 3' processing

(2010) Q. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex

(2009) Yongsheng Shi et al.   MOLECULAR CELL

Use of Bacterially Expressed dsRNA to Downregulate Entamoeba histolytica Gene Expression

(2009) Carlos F. Solis et al.   PLoS One

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation