Chimeric aptamers in cancer cell-targeted drug delivery

RNA aptamer against a cancer stem cell marker epithelial cell adhesion molecule

(2011) Sarah Shigdar et al.   CANCER SCIENCE

Role of nanomedicine in reversing drug resistance mediated by ATP binding cassette transporters and P-glycoprotein in melanoma

(2011) Jagat R Kanwar et al.   Nanomedicine

Effect of Nucleoside and Nucleotide Analog Reverse Transcriptase Inhibitors on Cell-Mediated Immune Functions

(2010) Laura Enomoto et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

An Aptamer Targeting the Apical-Loop Domain Modulates pri-miRNA Processing

(2010) Christina E. Lünse et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An RNA Aptamer with High Affinity and Broad Specificity for Zinc Finger Proteins

(2010) Tristen C. Weiss et al.   BIOCHEMISTRY

Prostate cancer cell death produced by the co-delivery of Bcl-xL shRNA and doxorubicin using an aptamer-conjugated polyplex

(2010) Eunjung Kim et al.   BIOMATERIALS

A nanocapsular combinatorial sequential drug delivery system for antiangiogenesis and anticancer activities

(2010) Zhe Wang et al.   BIOMATERIALS

The formulation of aptamer-coated paclitaxel–polylactide nanoconjugates and their targeting to cancer cells

(2010) Rong Tong et al.   BIOMATERIALS

PET/NIRF/MRI triple functional iron oxide nanoparticles

(2010) Jin Xie et al.   BIOMATERIALS

Effect of 3′-end capping of aptamer with various 2′,4′-bridged nucleotides: Enzymatic post-modification toward a practical use of polyclonal aptamers

(2010) Yuuya Kasahara et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Theophylline detection using an aptamer and DNA–gold nanoparticle conjugates

(2010) Jorge L. Chávez et al.   BIOSENSORS & BIOELECTRONICS

A cell-permeable dominant-negative survivin protein induces apoptosis and sensitizes prostate cancer cells to TNF-α therapy

(2010) Chun Hei Antonio Cheung et al.   Cancer Cell International

A combination of a DNA-chimera siRNA against PLK-1 and zoledronic acid suppresses the growth of malignant mesothelioma cells in vitro

(2010) Eri Kawata et al.   CANCER LETTERS

Survivin: A target from brain cancer to neurodegenerative disease

(2010) Sara Baratchi et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Recent Advances in Anti-Survivin Treatments for Cancer

(2010) R. Kanwar et al.   CURRENT MEDICINAL CHEMISTRY

MicroRNAs, epigenetics and disease

(2010) Asli Silahtaroglu et al.   Essays in Biochemistry

Strategies for the discovery of therapeutic aptamers

(2010) Xianbin Yang et al.   Expert Opinion on Drug Discovery

Targeting survivin in cancer: patent review

(2010) Jagat R Kanwar et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Antibody-aptamer functionalized fibre-optic biosensor for specific detection of Listeria monocytogenes from food

(2010) S.H. Ohk et al.   JOURNAL OF APPLIED MICROBIOLOGY

Prodrugs Forming High Drug Loading Multifunctional Nanocapsules for Intracellular Cancer Drug Delivery

(2010) Youqing Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Anionic Conjugated Polymer with Aptamer-Functionalized Silica Nanoparticle for Label-Free Naked-Eye Detection of Lysozyme in Protein Mixtures

(2010) Yanyan Wang et al.   LANGMUIR

Applications of aptamers in nanodelivery systems in cancer, eye and inflammatory diseases

(2010) Jagat R Kanwar et al.   Nanomedicine

Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay

(2010) Fernando Pastor et al.   NATURE

Viral RNA silencing suppressors (RSS): Novel strategy of viruses to ablate the host RNA interference (RNAi) defense system

(2010) Shalmali Bivalkar-Mehla et al.   VIRUS RESEARCH

Self-assembly of supramolecular aptamer structures for optical or electrochemical sensing

(2009) Ronit Freeman et al.   ANALYST

Single Quantum-Dot-Based Aptameric Nanosensor for Cocaine

(2009) Chun-yang Zhang et al.   ANALYTICAL CHEMISTRY

Generation of Highly Specific Aptamers via Micromagnetic Selection

(2009) Jiangrong Qian et al.   ANALYTICAL CHEMISTRY

Label-Free Fluorescent Aptamer Sensor Based on Regulation of Malachite Green Fluorescence

(2009) Weichen Xu et al.   ANALYTICAL CHEMISTRY

Aptamers as a model for functional evaluation of LNA and 2′-amino LNA

(2009) Frank J. Hernandez et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Recognition Imaging of Acetylated Chromatin Using a DNA Aptamer

(2009) Liyun Lin et al.   BIOPHYSICAL JOURNAL

Nanocarriers’ entry into the cell: relevance to drug delivery

(2009) Hervé Hillaireau et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Aptamers: from bench side research towards patented molecules with therapeutic applications

(2009) Paromita Majumder et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

A Nucleolin-Targeted Multimodal Nanoparticle Imaging Probe for Tracking Cancer Cells Using an Aptamer

(2009) D. W. Hwang et al.   JOURNAL OF NUCLEAR MEDICINE

Effect of Serum on an RNA Aptamer-Based Electrochemical Sensor for Theophylline

(2009) Elena E. Ferapontova et al.   LANGMUIR

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

(2009) Justin P Dassie et al.   NATURE BIOTECHNOLOGY

Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA

(2009) Kim A. Woodrow et al.   NATURE MATERIALS

Selection of DNA aptamers using atomic force microscopy

(2009) Yusuke Miyachi et al.   NUCLEIC ACIDS RESEARCH

A new method for the detection of ATP using a quantum-dot-tagged aptamer

(2008) Zhang Chen et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Real-Time Imaging of Protein Internalization Using Aptamer Conjugates

(2008) Wei Li et al.   ANALYTICAL CHEMISTRY

The Nucleolin Targeting Aptamer AS1411 Destabilizes Bcl-2 Messenger RNA in Human Breast Cancer Cells

(2008) S. Soundararajan et al.   CANCER RESEARCH

Superparamagnetic Iron Oxide Nanoparticle-Aptamer Bioconjugates for Combined Prostate Cancer Imaging and Therapy

(2008) Andrew Z. Wang et al.   ChemMedChem

SELEX with modified nucleotides

(2008) Anthony D Keefe et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

‘Iron-saturated’ lactoferrin is a potent natural adjuvant for augmenting cancer chemotherapy

(2008) Jagat R Kanwar et al.   IMMUNOLOGY AND CELL BIOLOGY

Novel Dual Inhibitory Function Aptamer–siRNA Delivery System for HIV-1 Therapy

(2008) Jiehua Zhou et al.   MOLECULAR THERAPY

Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers

(2008) F. Gu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA