Delineating the Structural Blueprint of the Pre-mRNA 3'-End Processing Machinery

Novel Modifications on C-terminal Domain of RNA Polymerase II Can Fine-tune the Phosphatase Activity of Ssu72

(2013) Yonghua Luo et al.   ACS Chemical Biology

Overlapping and distinct functions of CstF64 and CstF64  in mammalian mRNA 3' processing

(2013) C. Yao et al.   RNA

Alternative cleavage and polyadenylation: the long and short of it

(2013) Bin Tian et al.   TRENDS IN BIOCHEMICAL SCIENCES

Dynamic phosphorylation patterns of RNA polymerase II CTD during transcription

(2012) Martin Heidemann et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The Poly(A)-Binding Protein Nuclear 1 Suppresses Alternative Cleavage and Polyadenylation Sites

(2012) Mathias Jenal et al.   CELL

Novel interactions at the essential N-terminus of poly(A) polymerase that could regulate poly(A) addition inSaccharomyces cerevisiae

(2012) Chukwudi Ezeokonkwo et al.   FEBS LETTERS

The RNA polymerase II CTD coordinates transcription and RNA processing

(2012) J.-P. Hsin et al.   GENES & DEVELOPMENT

PARP1 Represses PAP and Inhibits Polyadenylation during Heat Shock

(2012) Dafne Campigli Di Giammartino et al.   MOLECULAR CELL

The τCstF-64 Polyadenylation Protein Controls Genome Expression in Testis

(2012) Wencheng Li et al.   PLoS One

Structural and biochemical analysis of the assembly and function of the yeast pre-mRNA 3' end processing complex CF I

(2012) R. P. Barnwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of the Rna14-Rna15 complex

(2012) A. R. Paulson et al.   RNA

Updating the RNA polymerase CTD code: adding gene-specific layers

(2012) Sylvain Egloff et al.   TRENDS IN GENETICS

Genome-wide Analysis of Pre-mRNA 3′ End Processing Reveals a Decisive Role of Human Cleavage Factor I in the Regulation of 3′ UTR Length

(2012) Georges Martin et al.   Cell Reports

The CTD code of RNA polymerase II: a structural view

(2012) Olga Jasnovidova et al.   Wiley Interdisciplinary Reviews-RNA

Reconstitution of CF IA from Overexpressed Subunits Reveals Stoichiometry and Provides Insights into Molecular Topology

(2011) James M. B. Gordon et al.   BIOCHEMISTRY

Structural basis of pre-mRNA recognition by the human cleavage factor Im complex

(2011) Heng Li et al.   CELL RESEARCH

Ending the message: poly(A) signals then and now

(2011) N. J. Proudfoot   GENES & DEVELOPMENT

Mechanisms and Consequences of Alternative Polyadenylation

(2011) Dafne Campigli Di Giammartino et al.   MOLECULAR CELL

The interaction of Pcf11 and Clp1 is needed for mRNA 3'-end formation and is modulated by amino acids in the ATP-binding site

(2011) M. A. Ghazy et al.   NUCLEIC ACIDS RESEARCH

An essential role for Clp1 in assembly of polyadenylation complex CF IA and Pol II transcription termination

(2011) Raphaël Haddad et al.   NUCLEIC ACIDS RESEARCH

The P-Loop Domain of Yeast Clp1 Mediates Interactions Between CF IA and CPF Factors in Pre-mRNA 3′ End Formation

(2011) Sandra Holbein et al.   PLoS One

The structure of human Cleavage Factor Imhints at functions beyond UGUA-specific RNA binding

(2011) Qin Yang et al.   RNA Biology

A flexible linker region in Fip1 is needed for efficient mRNA polyadenylation

(2011) C. Ezeokonkwo et al.   RNA

Hexameric architecture of CstF supported by CstF-50 homodimerization domain structure

(2011) M. Moreno-Morcillo et al.   RNA

Crystal Structure of a Human Cleavage Factor CFIm25/CFIm68/RNA Complex Provides an Insight into Poly(A) Site Recognition and RNA Looping

(2011) Qin Yang et al.   STRUCTURE

Structure and Activity of a Novel Archaeal β-CASP Protein with N-Terminal KH Domains

(2011) Ana P.G. Silva et al.   STRUCTURE

Locked Tether Formation by Cooperative Folding of Rna14p Monkeytail and Rna15p Hinge Domains in the Yeast CF IA Complex

(2011) Maria Moreno-Morcillo et al.   STRUCTURE

Structural biology of poly(A) site definition

(2011) Qin Yang et al.   Wiley Interdisciplinary Reviews-RNA

cis-Proline-mediated Ser(P)5Dephosphorylation by the RNA Polymerase II C-terminal Domain Phosphatase Ssu72

(2010) Jon W. Werner-Allen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Protein–Protein Contacts Facilitate mRNA 3′-Processing Signal Recognition by Rna15 and Hrp1

(2010) Thomas C. Leeper et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal structure of a dimeric archaeal Cleavage and Polyadenylation Specificity Factor

(2010) Bijàn Mir-Montazeri et al.   JOURNAL OF STRUCTURAL BIOLOGY

Interactions of CstF-64, CstF-77, and symplekin: Implications on localisation and function

(2010) Marc-David Ruepp et al.   MOLECULAR BIOLOGY OF THE CELL

Crystal structure of the human symplekin–Ssu72–CTD phosphopeptide complex

(2010) Kehui Xiang et al.   NATURE

Structure of the Rna15 RRM–RNA complex reveals the molecular basis of GU specificity in transcriptional 3′-end processing factors

(2010) Christina Pancevac et al.   NUCLEIC ACIDS RESEARCH

Structural basis of UGUA recognition by the Nudix protein CFIm25 and implications for a regulatory role in mRNA 3' processing

(2010) Q. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of an archaeal cleavage and polyadenylation specificity factor subunit from Pyrococcus horikoshii

(2010) Yuya Nishida et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

WD40 proteins propel cellular networks

(2010) Christian U. Stirnimann et al.   TRENDS IN BIOCHEMICAL SCIENCES

mRNA 3′ end processing and more-multiple functions of mammalian cleavage factor I-68

(2010) Marc-David Ruepp et al.   Wiley Interdisciplinary Reviews-RNA

The hunt for the 3′ endonuclease

(2010) Zbigniew Dominski   Wiley Interdisciplinary Reviews-RNA

Pre-mRNA 3′-end processing complex assembly and function

(2010) Serena Chan et al.   Wiley Interdisciplinary Reviews-RNA

Pre-mRNA Processing Reaches Back toTranscription and Ahead to Translation

(2009) Melissa J. Moore et al.   CELL

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

Poly(A) Tail Length Is Controlled by the Nuclear Poly(A)-binding Protein Regulating the Interaction between Poly(A) Polymerase and the Cleavage and Polyadenylation Specificity Factor

(2009) Uwe Kühn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Hinge Domain of the Cleavage Stimulation Factor Protein CstF-64 Is Essential for CstF-77 Interaction, Nuclear Localization, and Polyadenylation

(2009) J. Andrew Hockert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of the HEAT Domain from the Pre-mRNA Processing Factor Symplekin

(2009) Sarah A. Kennedy et al.   JOURNAL OF MOLECULAR BIOLOGY

The Essential N Terminus of the Pta1 Scaffold Protein Is Required for snoRNA Transcription Termination and Ssu72 Function but Is Dispensable for Pre-mRNA 3'-End Processing

(2009) M. A. Ghazy et al.   MOLECULAR AND CELLULAR BIOLOGY

A Core Complex of CPSF73, CPSF100, and Symplekin May Form Two Different Cleavage Factors for Processing of Poly(A) and Histone mRNAs

(2009) Kelly D. Sullivan et al.   MOLECULAR CELL

Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex

(2009) Yongsheng Shi et al.   MOLECULAR CELL

Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development

(2009) Z. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of Yeast Poly(A) Polymerase in Complex with a Peptide from Fip1, an Intrinsically Disordered Protein†‡

(2008) Gretchen Meinke et al.   BIOCHEMISTRY

Structural Basis of UV DNA-Damage Recognition by the DDB1–DDB2 Complex

(2008) Andrea Scrima et al.   CELL

3′ end mRNA processing: molecular mechanisms and implications for health and disease

(2008) Sven Danckwardt et al.   EMBO JOURNAL

Conserved motifs in both CPSF73 and CPSF100 are required to assemble the active endonuclease for histone mRNA 3′-end maturation

(2008) Nikolay G Kolev et al.   EMBO REPORTS

Sumoylation regulates multiple aspects of mammalian poly(A) polymerase function

(2008) V. Vethantham et al.   GENES & DEVELOPMENT

Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail

(2008) William F. Marzluff et al.   NATURE REVIEWS GENETICS

Structural insights into the dual activity of RNase J

(2008) Inés Li de la Sierra-Gallay et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure of the 25 kDa subunit of human cleavage factor I m

(2008) Molly Coseno et al.   NUCLEIC ACIDS RESEARCH

Structural basis for suppression of a host antiviral response by influenza A virus

(2008) K. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure and possible dimerization of the single RRM of human PABPN1

(2008) Honghua Ge et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The crystal structure of human cleavage and polyadenylation specific factor-5 reveals a dimeric Nudix protein with a conserved catalytic site

(2008) Lionel Trésaugues et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Human RNA 5'-kinase (hClp1) can function as a tRNA splicing enzyme in vivo

(2008) A. Ramirez et al.   RNA

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

(2008) R. Sandberg et al.   SCIENCE