Unveiling some FDA-approved drugs as inhibitors of the store-operated Ca2+ entry pathway

Intra-articular lentivirus-mediated gene therapy targeting CRACM1 for the treatment of collagen-induced arthritis

(2017) Shuang Liu et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

STIM1 Phosphorylation at Y361 Recruits Orai1 to STIM1 Puncta and Induces Ca2+ Entry

(2017) Pascal Yazbeck et al.   Scientific Reports

Store-operated CRAC channel inhibitors: opportunities and challenges

(2016) Chengsen Tian et al.   Future Medicinal Chemistry

Store-Operated Calcium Channels

(2015) Murali Prakriya et al.   PHYSIOLOGICAL REVIEWS

Leflunomide and teriflunomide: altering the metabolism of pyrimidines for the treatment of autoimmune diseases

(2015) Yara Dadalti Fragoso et al.   Expert Review of Clinical Pharmacology

Potent functional uncoupling between STIM1 and Orai1 by dimeric 2-aminodiphenyl borinate analogs

(2014) Eunan Hendron et al.   CELL CALCIUM

Identification of Orai1 Channel Inhibitors by Using Minimal Functional Domains to Screen Small Molecule Microarrays

(2014) Amir Masoud Sadaghiani et al.   CHEMISTRY & BIOLOGY

Upregulation of store-operated Ca2+ entry in the naïve CD4+ T cells with aberrant cytokine releasing in active rheumatoid arthritis

(2014) Shuang Liu et al.   IMMUNOLOGY AND CELL BIOLOGY

A comparison of various optimization algorithms of protein–ligand docking programs by fitness accuracy

(2014) Liyong Guo et al.   JOURNAL OF MOLECULAR MODELING

Review of Tolvaptan’s Pharmacokinetic and Pharmacodynamic Properties and Drug Interactions

(2014) Purav Bhatt et al.   Journal of Clinical Medicine

Molecular pharmacology of store-operated CRAC channels

(2013) Amit Jairaman et al.   Channels

Pharmacokinetics and pharmacodynamics of oral tolvaptan in patients with varying degrees of renal function

(2013) Susan E. Shoaf et al.   KIDNEY INTERNATIONAL

Pharmacokinetics and Pharmacodynamics of the Proton Pump Inhibitors

(2013) Jai Moo Shin et al.   Journal of Neurogastroenterology and Motility

An update of teriflunomide for treatment of multiple sclerosis

(2013) Paul O'Connor et al.   Therapeutics and Clinical Risk Management

e-Drug3D: 3D structure collections dedicated to drug repurposing and fragment-based drug design

(2012) Emilie Pihan et al.   BIOINFORMATICS

Novel pyrazole compounds for pharmacological discrimination between receptor-operated and store-operated Ca2+entry pathways

(2012) H Schleifer et al.   BRITISH JOURNAL OF PHARMACOLOGY

The action of selective CRAC channel blockers is affected by the Orai pore geometry

(2012) Isabella Derler et al.   CELL CALCIUM

Shape-Based Reprofiling of FDA-Approved Drugs for the H1 Histamine Receptor

(2012) Sridhar R. Vasudevan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Update on roflumilast, a phosphodiesterase 4 inhibitor for the treatment of chronic obstructive pulmonary disease

(2011) Klaus F. Rabe   BRITISH JOURNAL OF PHARMACOLOGY

Selective Activation of the Transcription Factor NFAT1 by Calcium Microdomains near Ca2+Release-activated Ca2+(CRAC) Channels

(2011) Pulak Kar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploring Polypharmacology Using a ROCS-Based Target Fishing Approach

(2011) Mohamed Diwan M. AbdulHameed et al.   Journal of Chemical Information and Modeling

Conformer Generation with OMEGA: Algorithm and Validation Using High Quality Structures from the Protein Databank and Cambridge Structural Database

(2010) Paul C. D. Hawkins et al.   Journal of Chemical Information and Modeling

Store-operated CRAC channels: function in health and disease

(2010) Anant B. Parekh   NATURE REVIEWS DRUG DISCOVERY

Small-Molecule Inhibitors of Store-Operated Calcium Entry

(2009) Zachary K. Sweeney et al.   ChemMedChem

Methods for studying store-operated calcium entry

(2008) Gary S. Bird et al.   METHODS