STIM1 Phosphorylation at Y361 Recruits Orai1 to STIM1 Puncta and Induces Ca2+ Entry

MicroRNA-150 Suppression of Angiopoetin-2 Generation and Signaling Is Crucial for Resolving Vascular InjurySignificance

(2016) Charu Rajput et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial p110γPI3K Mediates Endothelial Regeneration and Vascular Repair After Inflammatory Vascular InjuryCLINICAL PERSPECTIVE

(2016) Xiaojia Huang et al.   CIRCULATION

A STIM1-dependent 'trafficking trap' mechanism regulates Orai1 plasma membrane residence and Ca2+ influx levels

(2015) R. Hodeify et al.   JOURNAL OF CELL SCIENCE

Structural and Functional Mechanisms of CRAC Channel Regulation

(2015) Ann Hye-Ryong Shim et al.   JOURNAL OF MOLECULAR BIOLOGY

Nanoscale patterning of STIM1 and Orai1 during store-operated Ca2+entry

(2015) Stefano Perni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STIM1 dimers undergo unimolecular coupling to activate Orai1 channels

(2015) Yandong Zhou et al.   Nature Communications

Protective effect of adenosine receptors against lipopolysaccharide-induced acute lung injury

(2014) Joyce N. Gonzales et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A Coiled-coil Clamp Controls Both Conformation and Clustering of Stromal Interaction Molecule 1 (STIM1)

(2014) Marc Fahrner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cooperative Signaling via Transcription Factors NF-κB and AP1/c-Fos Mediates Endothelial Cell STIM1 Expression and Hyperpermeability in Response to Endotoxin

(2014) Auditi DebRoy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tyrosine 402 Phosphorylation of Pyk2 Is Involved in Ionomycin-Induced Neurotransmitter Release

(2014) Zhao Zhang et al.   PLoS One

A relay mechanism between EB1 and APC facilitate STIM1 puncta assembly at endoplasmic reticulum–plasma membrane junctions

(2013) Alexander Asanov et al.   CELL CALCIUM

The role of plasma membrane STIM1 and Ca2+entry in platelet aggregation. STIM1 binds to novel proteins in human platelets

(2013) A. Ambily et al.   CELLULAR SIGNALLING

The STIM1/Orai signaling machinery

(2013) Marc Fahrner et al.   Channels

Phosphorylation of STIM1 at ERK1/2 target sites regulates interaction with the microtubule plus-end binding protein EB1

(2013) E. Pozo-Guisado et al.   JOURNAL OF CELL SCIENCE

Activation of the Endoplasmic Reticulum Calcium Sensor STIM1 and Store-Operated Calcium Entry by Rotavirus Requires NSP4 Viroporin Activity

(2013) J. M. Hyser et al.   JOURNAL OF VIROLOGY

Conformational dynamics of STIM1 activation

(2013) Stefan Feske et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

STIMulating Stress Fibers in Endothelial Cells

(2013) T. Gudermann et al.   Science Signaling

STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry

(2013) Peter B. Stathopulos et al.   Nature Communications

STIM1 tyrosine-phosphorylation is required for STIM1-Orai1 association in human platelets

(2012) Esther Lopez et al.   CELLULAR SIGNALLING

Phosphoregulation of STIM1 Leads to Exclusion of the Endoplasmic Reticulum from the Mitotic Spindle

(2012) Jeremy T. Smyth et al.   CURRENT BIOLOGY

PYK2: A calcium-sensitive protein tyrosine kinase activated in response to fertilization of the zebrafish oocyte

(2012) Dipika Sharma et al.   DEVELOPMENTAL BIOLOGY

Phosphorylation of Stim1 at serine 575 via netrin-2/Cdo–activated ERK1/2 is critical for the promyogenic function of Stim1

(2012) Hye-Jin Lee et al.   MOLECULAR BIOLOGY OF THE CELL

The Acute Respiratory Distress Syndrome: Pathogenesis and Treatment

(2011) Michael A. Matthay et al.   Annual Review of Pathology-Mechanisms of Disease

Role of the STIM1 C-terminal Domain in STIM1 Clustering

(2011) Fang Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry

(2011) L. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of STIM1 at ERK1/2 target sites modulates store-operated calcium entry

(2010) E. Pozo-Guisado et al.   JOURNAL OF CELL SCIENCE

Essential Role for the CRAC Activation Domain in Store-dependent Oligomerization of STIM1

(2010) Elizabeth D. Covington et al.   MOLECULAR BIOLOGY OF THE CELL

Activation of STIM1-Orai1 Involves an Intramolecular Switching Mechanism

(2010) M. K. Korzeniowski et al.   Science Signaling

A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels

(2009) Takumi Kawasaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Recent progress on STIM1 domains controlling Orai activation

(2009) R. Schindl et al.   CELL CALCIUM

STIM1 Is a Calcium Sensor Specialized for Digital Signaling

(2009) Gary S. Bird et al.   CURRENT BIOLOGY

A single EF-hand isolated from STIM1 forms dimer in the absence and presence of Ca2+

(2009) Yun Huang et al.   FEBS Journal

The G protein βγ subunit mediates reannealing of adherens junctions to reverse endothelial permeability increase by thrombin

(2009) Nebojsa Knezevic et al.   JOURNAL OF EXPERIMENTAL MEDICINE

STIM and Orai: the long-awaited constituents of store-operated calcium entry

(2009) Péter Várnai et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Biophysical characterization of the EF-hand and SAM domain containing Ca2+ sensory region of STIM1 and STIM2

(2008) Le Zheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structural and Mechanistic Insights into STIM1-Mediated Initiation of Store-Operated Calcium Entry

(2008) Peter B. Stathopulos et al.   CELL

Stim1 and Orai1 Mediate CRAC Currents and Store-Operated Calcium Entry Important for Endothelial Cell Proliferation

(2008) Iskandar F. Abdullaev et al.   CIRCULATION RESEARCH

Activation of Sphingosine Kinase-1 Reverses the Increase in Lung Vascular Permeability Through Sphingosine-1-Phosphate Receptor Signaling in Endothelial Cells

(2008) Mohammad Tauseef et al.   CIRCULATION RESEARCH

STIM1 Is a MT-Plus-End-Tracking Protein Involved in Remodeling of the ER

(2008) Ilya Grigoriev et al.   CURRENT BIOLOGY

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

(2008) Masatsugu Oh-hora et al.   NATURE IMMUNOLOGY