Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy

A New Chapter for Diabetic Kidney Disease

(2017) Ian H. de Boer   NEW ENGLAND JOURNAL OF MEDICINE

Matrix metalloproteinase 9 induces endothelial-mesenchymal transition via Notch activation in human kidney glomerular endothelial cells

(2016) Ye Zhao et al.   BMC CELL BIOLOGY

Increased urinary lysophosphatidic acid in mouse with subtotal nephrectomy: potential involvement in chronic kidney disease

(2016) Koryun Mirzoyan et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Matrix Metalloproteinase-7 Is a Urinary Biomarker and Pathogenic Mediator of Kidney Fibrosis

(2016) Dong Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cathepsin L is crucial for the development of early experimental diabetic nephropathy

(2016) Marjolein Garsen et al.   KIDNEY INTERNATIONAL

Urinary peptidomics provides a noninvasive humanized readout of diabetic nephropathy in mice

(2016) Julie Klein et al.   KIDNEY INTERNATIONAL

Lysosomal protease cathepsin D; a new driver of apoptosis during acute kidney injury

(2016) Pasquale Cocchiaro et al.   Scientific Reports

Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease

(2016) Christopher Fox et al.   Scientific Reports

Improving the Mann–Whitney statistical test for feature selection: An approach in breast cancer diagnosis on mammography

(2015) Noel Pérez Pérez et al.   ARTIFICIAL INTELLIGENCE IN MEDICINE

Protein biomarkers for insulin resistance and type 2 diabetes risk in two large community cohorts

(2015) Christoph Nowak et al.   DIABETES

Diagnosis and Prediction of CKD Progression by Assessment of Urinary Peptides

(2015) J. P. Schanstra et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The emerging role of coagulation proteases in kidney disease

(2015) Thati Madhusudhan et al.   Nature Reviews Nephrology

Pro: Urine proteomics as a liquid kidney biopsy: no more kidney punctures!

(2015) H. Mischak   NEPHROLOGY DIALYSIS TRANSPLANTATION

Diabetic nephropathy: landmark clinical trials and tribulations

(2015) Gary C.W. Chan et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Diabetic nephropathy is associated with increased urine excretion of proteases plasmin, prostasin and urokinase and activation of amiloride-sensitive current in collecting duct cells

(2015) H. Andersen et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Urine matrix metalloproteinases and their extracellular inducer EMMPRIN in children with chronic kidney disease

(2015) Kinga Musiał et al.   RENAL FAILURE

Proteases and Protease Inhibitors of Urinary Extracellular Vesicles in Diabetic Nephropathy

(2015) Luca Musante et al.   Journal of Diabetes Research

Mechanisms of Cellular Proteostasis: Insights from Single-Molecule Approaches

(2014) Carlos J. Bustamante et al.   Annual Review of Biophysics

A Glimpse of Matrix Metalloproteinases in Diabetic Nephropathy

(2014) X. Xu et al.   CURRENT MEDICINAL CHEMISTRY

Tissue Kallikrein Mediates Pro-Inflammatory Pathways and Activation of Protease-Activated Receptor-4 in Proximal Tubular Epithelial Cells

(2014) Wai Han Yiu et al.   PLoS One

Identification of Urinary Peptide Biomarkers Associated with Rheumatoid Arthritis

(2014) Angelique Stalmach et al.   PLoS One

Cathepsin K Inhibitors: A Novel Target but Promising Approach in the Treatment of Osteoporosis

(2013) Asadul Helali et al.   CURRENT DRUG TARGETS

Defining cell-type specificity at the transcriptional level in human disease

(2013) Wenjun Ju et al.   GENOME RESEARCH

Proteasix: A tool for automated and large-scale prediction of proteases involved in naturally occurring peptide generation

(2013) Julie Klein et al.   PROTEOMICS

Poor histological lesions in IgA nephropathy may be reflected in blood and urine peptide profiling

(2013) Fredzzia Graterol et al.   BMC Nephrology

Proteases and Delayed Wound Healing

(2013) Sara M. McCarty et al.   Advances in Wound Care

Renal impairment and all-cause mortality in cardiovascular disease: effect modification by type 2 diabetes mellitus

(2012) Sharmini Selvarajah et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Transcriptome Analysis of Human Diabetic Kidney Disease

(2011) K. I. Woroniecka et al.   DIABETES

Matrix Metalloproteinase-7 as a Surrogate Marker Predicts Renal Wnt/ -Catenin Activity in CKD

(2011) W. He et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Human urinary peptide database for multiple disease biomarker discovery

(2011) Justyna Siwy et al.   Proteomics Clinical Applications

Extracellular Matrix Degradation and Remodeling in Development and Disease

(2011) P. Lu et al.   Cold Spring Harbor Perspectives in Biology

Macrophage Matrix Metalloproteinase-9 Mediates Epithelial-Mesenchymal Transition in Vitro in Murine Renal Tubular Cells

(2010) Thian Kui Tan et al.   AMERICAN JOURNAL OF PATHOLOGY

Detection of Functional Matrix Metalloproteinases by Zymography

(2010) Xueyou Hu et al.   Jove-Journal of Visualized Experiments

Standards of Medical Care in Diabetes--2009

(2009)   DIABETES CARE

Proteases: Multifunctional Enzymes in Life and Disease

(2008) Carlos López-Otín et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Towards Standard Protocols and Guidelines for Urine Proteomics: A Report on the Human Kidney and Urine Proteome Project (HKUPP) Symposium and Workshop 6 October 2007, Seoul, Korea and 1 November 2007, San Francisco, CA, USA

(2008) Tadashi Yamamoto et al.   PROTEOMICS

CE-MS analysis of the human urinary proteome for biomarker discovery and disease diagnostics

(2008) Joshua J. Coon et al.   Proteomics Clinical Applications