Cdk2 strengthens the intra-S checkpoint and counteracts cell cycle exit induced by DNA damage
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Title
Cdk2 strengthens the intra-S checkpoint and counteracts cell cycle exit induced by DNA damage
Authors
Keywords
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Journal
Scientific Reports
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-10-12
DOI
10.1038/s41598-017-12868-5
References
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Related references
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- (2016) Siwanon Jirawatnotai et al. DNA REPAIR
- A CDK2 activity signature predicts outcome in CDK2-low cancers
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- Hypersensitivity to DNA damage in antephase as a safeguard for genome stability
- (2016) Femke M. Feringa et al. Nature Communications
- Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation
- (2015) Sophia X. Pfister et al. CANCER CELL
- Senescence from G2 arrest, revisited
- (2015) Véronique Gire et al. CELL CYCLE
- Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase
- (2014) Erik Müllers et al. CELL CYCLE
- Transient Activation of p53 in G2 Phase Is Sufficient to Induce Senescence
- (2014) Lenno Krenning et al. MOLECULAR CELL
- Necessary and Sufficient Role for a Mitosis Skip in Senescence Induction
- (2014) Yoshikazu Johmura et al. MOLECULAR CELL
- Radiation-induced cellular senescence results from a slippage of long-term G2arrested cells into G1phase
- (2013) Caiyong Ye et al. CELL CYCLE
- Dosage of Dyrk1a Shifts Cells within a p21-Cyclin D1 Signaling Map to Control the Decision to Enter the Cell Cycle
- (2013) Jia-Yun Chen et al. MOLECULAR CELL
- Chemical Genetics Reveals a Specific Requirement for Cdk2 Activity in the DNA Damage Response and Identifies Nbs1 as a Cdk2 Substrate in Human Cells
- (2012) Lara Wohlbold et al. PLoS Genetics
- Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development
- (2011) Assaf C. Bester et al. CELL
- Switching Cdk2 On or Off with Small Molecules to Reveal Requirements in Human Cell Proliferation
- (2011) Karl A. Merrick et al. MOLECULAR CELL
- A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers
- (2011) Siwanon Jirawatnotai et al. NATURE
- Cdk-mediated phosphorylation of Chk1 is required for efficient activation and full checkpoint proficiency in response to DNA damage
- (2011) N Xu et al. ONCOGENE
- Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional
- (2011) G Lossaint et al. ONCOGENE
- Behind the wheel and under the hood: Functions of cyclin-dependent kinases in response to DNA damage
- (2009) Lara Wohlbold et al. DNA REPAIR
- Overall Cdk activity modulates the DNA damage response in mammalian cells
- (2009) Antonio Cerqueira et al. JOURNAL OF CELL BIOLOGY
- A Bifunctional Regulatory Element in Human Somatic Wee1 Mediates Cyclin A/Cdk2 Binding and Crm1-Dependent Nuclear Export
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- Cdk2 suppresses cellular senescence induced by the c-myc oncogene
- (2009) Stefano Campaner et al. NATURE CELL BIOLOGY
- Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer
- (2008) Martin F. Lavin NATURE REVIEWS MOLECULAR CELL BIOLOGY
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