TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice

TRPC6 G757D Loss-of-Function Mutation Associates with FSGS

(2016) M. Riehle et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Dynamic NHERF interaction with TRPC4/5 proteins is required for channel gating by diacylglycerol

(2016) Ursula Storch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Purinergic P2Y6receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II–induced hypertension

(2016) Akiyuki Nishimura et al.   Science Signaling

TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling

(2016) Naoyuki Kitajima et al.   Scientific Reports

Purinergic P2Y6receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II–induced hypertension

(2016) Akiyuki Nishimura et al.   Science Signaling

TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis

(2016) Takuro Numaga-Tomita et al.   Scientific Reports

Comparison of the cardioprotective and renoprotective effects of the L/N-type calcium channel blocker, cilnidipine, in adriamycin-treated spontaneously-hypertensive rats

(2015) Shizuka Aritomi et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Diabetic Cardiovascular Disease Induced by Oxidative Stress

(2015) Yosuke Kayama et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy

(2014) K. Seo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A convenient method to assess chemical modification of protein thiols by electrophilic metals

(2013) Takashi Toyama et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

A TRPC6-Dependent Pathway for Myofibroblast Transdifferentiation and Wound Healing In Vivo

(2012) Jennifer Davis et al.   DEVELOPMENTAL CELL

Mitochondria in cardiac hypertrophy and heart failure

(2012) Mariana G. Rosca et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration

(2012) Motohiro Nishida et al.   Nature Chemical Biology

Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart

(2012) Jian Xie et al.   Nature Communications

TRPC3-mediated Ca2+ influx contributes to Rac1-mediated production of reactive oxygen species in MLP-deficient mouse hearts

(2011) Naoyuki Kitajima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TRPC1 proteins confer PKC and phosphoinositol activation on native heteromeric TRPC1/C5 channels in vascular smooth muscle: comparative study of wild-type and TRPC1−/− mice

(2011) Jian Shi et al.   FASEB JOURNAL

Signal Transduction by Mitochondrial Oxidants

(2011) Toren Finkel   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of TRPC6 Channels at Thr69Is Required for Anti-hypertrophic Effects of Phosphodiesterase 5 Inhibition

(2010) Motohiro Nishida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ca 2+ influx and protein scaffolding via TRPC3 sustain PKCβ and ERK activation in B cells

(2010) Takuro Numaga et al.   JOURNAL OF CELL SCIENCE

Synergistic Activation of Vascular TRPC6 Channel by Receptor and Mechanical Stimulation via Phospholipase C/Diacylglycerol and Phospholipase A 2 /ω-Hydroxylase/20-HETE Pathways

(2009) Ryuji Inoue et al.   CIRCULATION RESEARCH

NADPH oxidase contributes to conversion of cardiac myocytes to a proinflammatory phenotype in sepsis

(2009) Jun Wu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Intracellular calcium strongly potentiates agonist-activated TRPC5 channels

(2009) Nathaniel T. Blair et al.   JOURNAL OF GENERAL PHYSIOLOGY

Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound

(2009) S. Kiyonaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

P2Y6 receptor-Gα12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis

(2008) Motohiro Nishida et al.   EMBO JOURNAL

Roles of TRP channels in the development of cardiac hypertrophy

(2008) Motohiro Nishida et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY