Purinergic P2Y6receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II–induced hypertension

Dual agonist occupancy of AT1-R–α2C-AR heterodimers results in atypical Gs-PKA signaling

(2015) Morgane Bellot et al.   Nature Chemical Biology

P2Y 6 Deficiency Limits Vascular Inflammation and Atherosclerosis in Mice

(2014) Peter Stachon et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Age Determines the Magnitudes of Angiotensin II-Induced Contractions, mRNA, and Protein Expression of Angiotensin Type 1 Receptors in Rat Carotid Arteries

(2013) Z. Vamos et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Allosteric interactions within the AT1 angiotensin receptor homodimer: Role of the conserved DRY motif

(2012) Bence Szalai et al.   BIOCHEMICAL PHARMACOLOGY

Procontractile G protein–mediated signaling pathways antagonistically regulate smooth muscle differentiation in vascular remodeling

(2012) Till F. Althoff et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Purinergic Receptor Type 6 Contributes to Airway Inflammation and Remodeling in Experimental Allergic Airway Inflammation

(2011) Rodolfo Paula Vieira et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cilostazol Suppresses Angiotensin II–Induced Vasoconstriction via Protein Kinase A–Mediated Phosphorylation of the Transient Receptor Potential Canonical 6 Channel

(2011) Kinue Nishioka et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

AT1R-CB1R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II

(2011) Raphael Rozenfeld et al.   EMBO JOURNAL

Selective induction of endothelial P2Y6 nucleotide receptor promotes vascular inflammation

(2010) A.-K. Riegel et al.   BLOOD

The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure

(2010) Christophe Guilluy et al.   NATURE MEDICINE

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

(2009) Michael R. Elliott et al.   NATURE

P2Y6 receptor-Gα12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis

(2008) Motohiro Nishida et al.   EMBO JOURNAL

Knockout Mice Reveal a Role for P2Y6 Receptor in Macrophages, Endothelial Cells, and Vascular Smooth Muscle Cells

(2008) I. Bar et al.   MOLECULAR PHARMACOLOGY