Brain Inflammation, Blood Brain Barrier dysfunction and Neuronal Synaptophysin Decrease after Inhalation Exposure to Titanium Dioxide Nano-aerosol in Aging Rats

The Role of the Blood Brain Barrier in Neurodegenerative Disorders and their Treatment

(2018) Alan M. Palmer   JOURNAL OF ALZHEIMERS DISEASE

Biopersistence and translocation to extrapulmonary organs of titanium dioxide nanoparticles after subacute inhalation exposure to aerosol in adult and elderly rats

(2017) Laurent Gaté et al.   TOXICOLOGY LETTERS

Toxicokinetics of titanium dioxide (TiO2) nanoparticles after inhalation in rats

(2017) Igor Pujalté et al.   TOXICOLOGY LETTERS

Mineralization of TiO2 nanoparticles for the determination of titanium in rat tissues

(2016) Jérôme Devoy et al.   JOURNAL OF ANALYTICAL CHEMISTRY

Rapid Transport within Cerebral Perivascular Spaces Underlies Widespread Tracer Distribution in the Brain after Intranasal Administration

(2015) Jeffrey J Lochhead et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Intratracheally instilled titanium dioxide nanoparticles translocate to heart and liver and activate complement cascade in the heart of C57BL/6 mice

(2015) Mainul Husain et al.   Nanotoxicology

Pulmonary clearance kinetics and extrapulmonary translocation of seven titanium dioxide nano- and submicron materials following intratracheal administration in rats

(2015) Naohide Shinohara et al.   Nanotoxicology

Vascular dysfunction in the pathogenesis of Alzheimer's disease — A review of endothelium-mediated mechanisms and ensuing vicious circles

(2015) Luigi Yuri Di Marco et al.   NEUROBIOLOGY OF DISEASE

Tissue biodistribution of intravenously administrated titanium dioxide nanoparticles revealed blood-brain barrier clearance and brain inflammation in rat

(2015) Clémence Disdier et al.   Particle and Fibre Toxicology

Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus

(2015) G. Aleph Prieto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanotechnology in the real world: Redeveloping the nanomaterial consumer products inventory

(2015) Marina E Vance et al.   Beilstein Journal of Nanotechnology

Blood–brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment

(2015) Mina Elahy et al.   Immunity & Ageing

Particulate matter and risk of parkinson disease in a large prospective study of women

(2014) Natalia Palacios et al.   Environmental Health

Th2 Factors May Be Involved in TiO2 NP-Induced Hepatic Inflammation

(2014) Jie Hong et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Polyunsaturated fatty acids and their metabolites in brain function and disease

(2014) Richard P. Bazinet et al.   NATURE REVIEWS NEUROSCIENCE

TiO2 Nanoparticles Induced Hippocampal Neuroinflammation in Mice

(2014) Yuguan Ze et al.   PLoS One

Dose-dependent clearance kinetics of intratracheally administered titanium dioxide nanoparticles in rat lung

(2014) Naohide Shinohara et al.   TOXICOLOGY

Synchrotron radiation X-ray fluorescence analysis of biodistribution and pulmonary toxicity of nanoscale titanium dioxide in mice

(2013) Jichao Zhang et al.   ANALYST

Molecular mechanism of titanium dioxide nanoparticles-induced oxidative injury in the brain of mice

(2013) Yuguan Ze et al.   CHEMOSPHERE

Neurotoxicity and gene-expressed profile in brain-injured mice caused by exposure to titanium dioxide nanoparticles

(2013) Yuguan Ze et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Neurotoxic characteristics of spatial recognition damage of the hippocampus in mice following subchronic peroral exposure to TiO2 nanoparticles

(2013) Yuguan Ze et al.   JOURNAL OF HAZARDOUS MATERIALS

Susceptibility of juvenile and adult blood–brain barrier to endothelin-1: regulation of P-glycoprotein and breast cancer resistance protein expression and transport activity

(2012) Rania Harati et al.   Journal of Neuroinflammation

Intranasal delivery of biologics to the central nervous system

(2011) Jeffrey J. Lochhead et al.   ADVANCED DRUG DELIVERY REVIEWS

In vitro evidence of dysregulation of blood–brain barrier function after acute and repeated/long-term exposure to TiO2 nanoparticles

(2011) Emilie Brun et al.   BIOMATERIALS

Effects of aging on blood brain barrier and matrix metalloproteases following controlled cortical impact in mice

(2011) Phil Lee et al.   EXPERIMENTAL NEUROLOGY

Cerebral microvascular endothelium and the pathogenesis of neurodegenerative diseases

(2011) Paula Grammas et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

A Strategy for Assessing Workplace Exposures to Nanomaterials

(2011) Gurumurthy Ramachandran et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE

In VitroPrimary Human and Animal Cell-Based Blood−Brain Barrier Models as a Screening Tool in Drug Discovery

(2011) Olivier Lacombe et al.   MOLECULAR PHARMACEUTICS

Rutile TiO2 particles exert size and surface coating dependent retention and lesions on the murine brain

(2011) Lili Zhang et al.   TOXICOLOGY LETTERS

Systematic Influence Induced by 3 nm Titanium Dioxide Following Intratracheal Instillation of Mice

(2010) Yufeng Li et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

The Aging Stress Response

(2010) Marcia C. Haigis et al.   MOLECULAR CELL

Reproductive age-related changes in the blood brain barrier: Expression of IgG and tight junction proteins

(2009) Shameena Bake et al.   MICROVASCULAR RESEARCH

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Detection of behavioral alterations and learning deficits in mice lacking synaptophysin

(2009) U. Schmitt et al.   NEUROSCIENCE

Air pollution: mechanisms of neuroinflammation and CNS disease

(2009) Michelle L. Block et al.   TRENDS IN NEUROSCIENCES

Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO2 nanoparticles

(2008) Jiangxue Wang et al.   TOXICOLOGY

Potential neurological lesion after nasal instillation of TiO2 nanoparticles in the anatase and rutile crystal phases

(2008) J WANG et al.   TOXICOLOGY LETTERS