Obesity-induces Organ and Tissue Specific Tight Junction Restructuring and Barrier Deregulation by Claudin Switching

Claudin-1 promotes TNF-α-induced epithelial-mesenchymal transition and migration in colorectal adenocarcinoma cells

(2016) Ajaz A. Bhat et al.   EXPERIMENTAL CELL RESEARCH

Paracellular epithelial sodium transport maximizes energy efficiency in the kidney

(2016) Lei Pei et al.   JOURNAL OF CLINICAL INVESTIGATION

Claudin-1, -2, -4, and -5: comparison of expression levels and distribution in equine tissues

(2016) Bonn Lee et al.   Journal of Veterinary Science

Claudin proteins, outside-in signaling, and carcinogenesis

(2016) Amar B. Singh et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Tumor necrosis factor-α induces a biphasic change in claudin-2 expression in tubular epithelial cells: role in barrier functions

(2015) Yasaman Amoozadeh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Autophagy Enhances Intestinal Epithelial Tight Junction Barrier Function by Targeting Claudin-2 Protein Degradation

(2015) Prashant K. Nighot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-fat Diet-induced Intestinal Hyperpermeability is Associated with Increased Bile Acids in the Large Intestine of Mice

(2015) Yuki Murakami et al.   JOURNAL OF FOOD SCIENCE

Intestinal Permeability in Inflammatory Bowel Disease: Pathogenesis, Clinical Evaluation, and Therapy of Leaky Gut

(2015) Andrea Michielan et al.   MEDIATORS OF INFLAMMATION

PANTHER version 10: expanded protein families and functions, and analysis tools

(2015) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

Claudins and cancer: Fall of the soldiers entrusted to protect the gate and keep the barrier intact

(2015) Amar B. Singh et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Tight junction CLDN2 gene is a direct target of the vitamin D receptor

(2015) Yong-guo Zhang et al.   Scientific Reports

Obesity, inflammation, and the gut microbiota

(2015) Amanda J Cox et al.   Lancet Diabetes & Endocrinology

Prevalence of Childhood and Adult Obesity in the United States, 2011-2012

(2014) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Targeted colonic claudin-2 expression renders resistance to epithelial injury, induces immune suppression and protects from colitis

(2014) R Ahmad et al.   Mucosal Immunology

The pathophysiology of hypertension in patients with obesity

(2014) Vincent G. DeMarco et al.   Nature Reviews Endocrinology

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Claudin-7 expression induces mesenchymal to epithelial transformation (MET) to inhibit colon tumorigenesis

(2014) A A Bhat et al.   ONCOGENE

Obesity and colorectal cancer

(2013) Mark Hull et al.   GUT

Claudin-1 regulates intestinal epithelial homeostasis through the modulation of Notch-signalling

(2013) Jillian L Pope et al.   GUT

Salmonella Infection Upregulates the Leaky Protein Claudin-2 in Intestinal Epithelial Cells

(2013) Yong-guo Zhang et al.   PLoS One

Body Mass Index and Renal Cell Cancer

(2012) Jennifer L. Beebe-Dimmer et al.   EPIDEMIOLOGY

Loss of Claudins 2 and 15 From Mice Causes Defects in Paracellular Na+ Flow and Nutrient Transport in Gut and Leads to Death from Malnutrition

(2012) Masami Wada et al.   GASTROENTEROLOGY

Probiotic Bacteria Induce Maturation of Intestinal Claudin 3 Expression and Barrier Function

(2011) Ravi M. Patel et al.   AMERICAN JOURNAL OF PATHOLOGY

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Inflammation and Disruption of the Mucosal Architecture in Claudin-7–Deficient Mice

(2011) Lei Ding et al.   GASTROENTEROLOGY

Interleukin-6 (IL-6) Regulates Claudin-2 Expression and Tight Junction Permeability in Intestinal Epithelium

(2011) Takuya Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammatory links between obesity and metabolic disease

(2011) Carey N. Lumeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation

(2011) P Dhawan et al.   ONCOGENE

Fatty acid detection during food consumption and digestion: Associations with ingestive behavior and obesity

(2011) Jessica E. Stewart et al.   PROGRESS IN LIPID RESEARCH

Calcium Metabolism in Health and Disease

(2010) M. Peacock   Clinical Journal of the American Society of Nephrology

Epithelial Myosin Light Chain Kinase Activation Induces Mucosal Interleukin-13 Expression to Alter Tight Junction Ion Selectivity

(2010) Christopher R. Weber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic Inflammation in Obesity and the Metabolic Syndrome

(2010) Rosário Monteiro et al.   MEDIATORS OF INFLAMMATION

Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression in LETO and OLETF rats

(2010) Takuya Suzuki et al.   Nutrition & Metabolism

Claudin-4 forms paracellular chloride channel in the kidney and requires claudin-8 for tight junction localization

(2010) J. Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Claudin-2–deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules

(2010) Shigeaki Muto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Claudin Family of Proteins and Cancer: An Overview

(2010) Amar B. Singh et al.   Journal of Oncology

TNFα up-regulates claudin-2 expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling

(2009) J. Mankertz et al.   CELL AND TISSUE RESEARCH

Annual Medical Spending Attributable To Obesity: Payer-And Service-Specific Estimates

(2009) Eric A. Finkelstein et al.   HEALTH AFFAIRS

Regulation and roles for claudin-family tight junction proteins

(2009) Mary K. Findley et al.   IUBMB LIFE

Physiology and Function of the Tight Junction

(2009) J. M. Anderson et al.   Cold Spring Harbor Perspectives in Biology

Tight Junction Proteins Claudin-2 and -12 Are Critical for Vitamin D-dependent Ca2+ Absorption between Enterocytes

(2008) Hiroki Fujita et al.   MOLECULAR BIOLOGY OF THE CELL

Megaintestine in Claudin-15–Deficient Mice

(2007) Atsushi Tamura et al.   GASTROENTEROLOGY