Pepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Pepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage
Authors
Keywords
-
Journal
Scientific Reports
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-08-21
DOI
10.1038/s41598-017-09808-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity
- (2017) Marjolein Soethoudt et al. Nature Communications
- Targeted metabolomics shows plasticity in the evolution of signaling lipids and uncovers old and new endocannabinoids in the plant kingdom
- (2017) María Salomé Gachet et al. Scientific Reports
- Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe
- (2016) Robert B. Laprairie et al. ACS Chemical Neuroscience
- Crystal Structure of the Human Cannabinoid Receptor CB 1
- (2016) Tian Hua et al. CELL
- The CB2 receptor and its role as a regulator of inflammation
- (2016) Caroline Turcotte et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- High-resolution crystal structure of the human CB1 cannabinoid receptor
- (2016) Zhenhua Shao et al. NATURE
- Effects of the cannabinoid 1 receptor peptide ligands hemopressin, (m)RVD-hemopressin(α) and (m)VD-hemopressin(α) on memory in novel object and object location recognition tasks in normal young and Aβ 1–42 -treated mice
- (2016) Rui-san Zhang et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Hemopressin Peptides as Modulators of the Endocannabinoid System and their Potential Applications as Therapeutic Tools
- (2016) Giorgia Macedonio et al. PROTEIN AND PEPTIDE LETTERS
- The Cannabinoid Receptor 2 Protects Against Alcoholic Liver Disease Via a Macrophage Autophagy-Dependent Pathway
- (2016) Timothé Denaës et al. Scientific Reports
- Site-specific Substitutions Eliminate Aggregation Properties of Hemopressin
- (2015) Benben Song et al. Chemical Biology & Drug Design
- Localization and production of peptide endocannabinoids in the rodent CNS and adrenal medulla
- (2015) Stefanie C. Hofer et al. NEUROPHARMACOLOGY
- Aiming for allosterism: Evaluation of allosteric modulators of CB1 in a neuronal model
- (2015) Alex Straiker et al. PHARMACOLOGICAL RESEARCH
- The Endocannabinoid System: Pivotal Orchestrator of Obesity and Metabolic Disease
- (2015) Wilfrid Mazier et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Endocannabinoid signaling at the periphery: 50 years after THC
- (2015) Mauro Maccarrone et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Functionalization of β-Caryophyllene Generates Novel Polypharmacology in the Endocannabinoid System
- (2014) Andrea Chicca et al. ACS Chemical Biology
- One-pot heterogeneous synthesis of Δ3-tetrahydrocannabinol analogues and xanthenes showing differential binding to CB1 and CB2 receptors
- (2014) Ornelio Rosati et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Modeling, Molecular Dynamics Simulation, and Mutation Validation for Structure of Cannabinoid Receptor 2 Based on Known Crystal Structures of GPCRs
- (2014) Zhiwei Feng et al. Journal of Chemical Information and Modeling
- Experimental Cannabinoid 2 Receptor-Mediated Immune Modulation in Sepsis
- (2014) J. Sardinha et al. MEDIATORS OF INFLAMMATION
- Early phytocannabinoid chemistry to endocannabinoids and beyond
- (2014) Raphael Mechoulam et al. NATURE REVIEWS NEUROSCIENCE
- Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy
- (2014) Tony Jourdan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pregnenolone Can Protect the Brain from Cannabis Intoxication
- (2014) Monique Vallée et al. SCIENCE
- Cannabinoid signaling and liver therapeutics
- (2013) Ariane Mallat et al. JOURNAL OF HEPATOLOGY
- A pharmacological organization of G protein–coupled receptors
- (2013) Henry Lin et al. NATURE METHODS
- Cannabinoid receptor trafficking in peripheral cells is dynamically regulated by a binary biochemical switch
- (2012) Jonas Kleyer et al. BIOCHEMICAL PHARMACOLOGY
- Identification and Quantification of a New Family of Peptide Endocannabinoids (Pepcans) Showing Negative Allosteric Modulation at CB1Receptors
- (2012) Mark Bauer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Is lipid signaling through cannabinoid 2 receptors part of a protective system?
- (2011) P. Pacher et al. PROGRESS IN LIPID RESEARCH
- Hemopressins and other hemoglobin-derived peptides in mouse brain: comparison between brain, blood, and heart peptidome and regulation inCpefat/fatmice
- (2010) Julia S. Gelman et al. JOURNAL OF NEUROCHEMISTRY
- International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2
- (2010) R. G. Pertwee et al. PHARMACOLOGICAL REVIEWS
- Constitutive activity of cannabinoid-2 (CB2) receptors plays an essential role in the protean agonism of (+)AM1241 and L768242
- (2009) I Mancini et al. BRITISH JOURNAL OF PHARMACOLOGY
- Novel endogenous peptide agonists of cannabinoid receptors
- (2009) Ivone Gomes et al. FASEB JOURNAL
- Biology and therapeutic potential of cannabinoid CB2receptor inverse agonists
- (2007) C A Lunn et al. BRITISH JOURNAL OF PHARMACOLOGY
- Endocannabinoids and cannabinoid receptors in ischaemia-reperfusion injury and preconditioning
- (2007) P Pacher et al. BRITISH JOURNAL OF PHARMACOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation