Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint

Co-inhibition of polo-like kinase 1 and Aurora kinases promotes mitotic catastrophe

(2015) Jingjing Li et al.   Oncotarget

Plk1 and Mps1 Cooperatively Regulate the Spindle Assembly Checkpoint in Human Cells

(2015) Conrad von Schubert et al.   Cell Reports

Polo-like kinase-1 triggers histone phosphorylation by Haspin in mitosis

(2014) Linli Zhou et al.   EMBO REPORTS

Mitotic arrest and slippage induced by pharmacological inhibition of Polo-like kinase 1

(2014) Monika Raab et al.   Molecular Oncology

Mitosis and apoptosis: how is the balance set?

(2013) Caroline H Topham et al.   CURRENT OPINION IN CELL BIOLOGY

Drosophila Polo regulates the spindle assembly checkpoint through Mps1-dependent BubR1 phosphorylation

(2013) Carlos Conde et al.   EMBO JOURNAL

Bora and Aurora-A continue to activate Plk1 in mitosis

(2013) Wytse Bruinsma et al.   JOURNAL OF CELL SCIENCE

Autoinhibition and Polo-Dependent Multisite Phosphorylation Restrict Activity of the Histone H3 Kinase Haspin to Mitosis

(2013) Cristina Ghenoiu et al.   MOLECULAR CELL

Polo-like kinase-1 regulates kinetochore–microtubule dynamics and spindle checkpoint silencing

(2012) Dan Liu et al.   JOURNAL OF CELL BIOLOGY

Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation

(2012) Fangwei Wang et al.   JOURNAL OF CELL BIOLOGY

A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B

(2012) Anna De Antoni et al.   JOURNAL OF CELL BIOLOGY

The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

(2012) Mar Carmena et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Chromosomal Passenger Complex Activates Polo Kinase at Centromeres

(2012) Mar Carmena et al.   PLOS BIOLOGY

A Positive Feedback Loop Involving Haspin and Aurora B Promotes CPC Accumulation at Centromeres in Mitosis

(2011) Fangwei Wang et al.   CURRENT BIOLOGY

Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction

(2011) Stefano Santaguida et al.   EMBO JOURNAL

Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis

(2011) Adrian T. Saurin et al.   Nature Communications

Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine

(2010) Stefano Santaguida et al.   JOURNAL OF CELL BIOLOGY

Phosphorylation of the CPC by Cdk1 promotes chromosome bi-orientation

(2010) Tatsuya Tsukahara et al.   NATURE

Histone H3 Thr-3 Phosphorylation by Haspin Positions Aurora B at Centromeres in Mitosis

(2010) Fangwei Wang et al.   SCIENCE

Aurora B kinase activation requires survivin priming phosphorylation by PLK1

(2010) Youjun Chu et al.   Journal of Molecular Cell Biology

BI 6727, A Polo-like Kinase Inhibitor with Improved Pharmacokinetic Profile and Broad Antitumor Activity

(2009) D. Rudolph et al.   CLINICAL CANCER RESEARCH

Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells

(2009) Aniek Janssen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of H2A by Bub1 Prevents Chromosomal Instability Through Localizing Shugoshin

(2009) S. A. Kawashima et al.   SCIENCE

Cancer Cells Display Profound Intra- and Interline Variation following Prolonged Exposure to Antimitotic Drugs

(2008) Karen E. Gascoigne et al.   CANCER CELL

Mps1 Phosphorylates Borealin to Control Aurora B Activity and Chromosome Alignment

(2008) Nannette Jelluma et al.   CELL

Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly

(2008) Michael J. Emanuele et al.   JOURNAL OF CELL BIOLOGY