Glycogen synthase kinase 3β inhibitors prevent hepatitis C virus release/assembly through perturbation of lipid metabolism

FIG4 is a hepatitis C virus particle-bound protein implicated in virion morphogenesis and infectivity with cholesteryl ester modulation potential

(2016) Jessica Cottarel et al.   JOURNAL OF GENERAL VIROLOGY

Inhibition of glycogen synthase kinase 3β promotes autophagy to protect mice from acute liver failure mediated by peroxisome proliferator-activated receptor α

(2016) F Ren et al.   Cell Death & Disease

Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases

(2015) Eleonore Beurel et al.   PHARMACOLOGY & THERAPEUTICS

MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells

(2015) Diego Ploper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic hepatitis C virus infection and lipoprotein metabolism

(2015) Yoshio Aizawa   WORLD JOURNAL OF GASTROENTEROLOGY

Hepatitis C Virus RNA Replication and Assembly: Living on the Fat of the Land

(2014) David Paul et al.   Cell Host & Microbe

Apolipoprotein E Likely Contributes to a Maturation Step of Infectious Hepatitis C Virus Particles and Interacts with Viral Envelope Glycoproteins

(2014) J.-Y. Lee et al.   JOURNAL OF VIROLOGY

Human serum leads to differentiation of human hepatoma cells, restoration of very-low-density lipoprotein secretion, and a 1000-fold increase in HCV Japanese fulminant hepatitis type 1 titers

(2013) Rineke H.G. Steenbergen et al.   HEPATOLOGY

Very-Low-Density Lipoprotein (VLDL)-Producing and Hepatitis C Virus-Replicating HepG2 Cells Secrete No More Lipoviroparticles than VLDL-Deficient Huh7.5 Cells

(2013) B. Jammart et al.   JOURNAL OF VIROLOGY

Apolipoprotein E Codetermines Tissue Tropism of Hepatitis C Virus and Is Crucial for Viral Cell-to-Cell Transmission by Contributing to a Postenvelopment Step of Assembly

(2013) K. Hueging et al.   JOURNAL OF VIROLOGY

Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention

(2013) J A McCubrey et al.   LEUKEMIA

Mechanism and Physiological Significance of Growth Factor-Related Autophagy

(2013) Terytty Yang Li et al.   PHYSIOLOGY

Differential Expression of Candidate Virus Receptors in Human T Lymphocytes Prone or Resistant to Infection with Patient-Derived Hepatitis C Virus

(2013) Mohammed A. Sarhan et al.   PLoS One

Patient-derived hepatitis C virus and JFH-1 clones differ in their ability to infect human hepatoma cells and lymphocytes

(2012) M. A. Sarhan et al.   JOURNAL OF GENERAL VIROLOGY

A Genetic Interaction between the Core and NS3 Proteins of Hepatitis C Virus Is Essential for Production of Infectious Virus

(2011) D. M. Jones et al.   JOURNAL OF VIROLOGY

A New Model to Produce Infectious Hepatitis C Virus without the Replication Requirement

(2011) Miriam Triyatni et al.   PLoS Pathogens

Lipoprotein profiles in SCID/uPA mice transplanted with human hepatocytes become human-like and correlate with HCV infection success

(2010) Rineke H. G. Steenbergen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

ACSL3 and GSK-3β are essential for lipid upregulation induced by endoplasmic reticulum stress in liver cells

(2010) Yung-Sheng Chang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

GSK3 signalling in neural development

(2010) Eun-Mi Hur et al.   NATURE REVIEWS NEUROSCIENCE

Diet-Dependent Genetic and Genomic Imprinting Effects on Obesity in Mice

(2010) James M. Cheverud et al.   Obesity

The Akt–SREBP nexus: cell signaling meets lipid metabolism

(2010) James R. Krycer et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The cyclophilin inhibitor Debio 025 combined with PEG IFNα2a significantly reduces viral load in treatment-naïve hepatitis C patients

(2009) Robert Flisiak et al.   HEPATOLOGY

The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production

(2009) Oscar Gonzalez et al.   HEPATOLOGY

Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication

(2009) J. Borawski et al.   JOURNAL OF VIROLOGY

GSK3: a multifaceted kinase in Wnt signaling

(2009) Dianqing Wu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus

(2008) R. S. Russell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA