ERLIN2 promotes breast cancer cell survival by modulating endoplasmic reticulum stress pathways

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

(2011) Kezhong Zhang et al.   EMBO JOURNAL

ZNF703is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium

(2011) Daniel G. Holland et al.   EMBO Molecular Medicine

ZNF703gene amplification at 8p12 specifies luminal B breast cancer

(2011) Fabrice Sircoulomb et al.   EMBO Molecular Medicine

Membrane-associated Ubiquitin Ligase Complex Containing gp78 Mediates Sterol-accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase

(2011) Youngah Jo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Unfolded Protein Response: Integrating Stress Signals Through the Stress Sensor IRE1α

(2011) Claudio Hetz et al.   PHYSIOLOGICAL REVIEWS

Regulation of basal cellular physiology by the homeostatic unfolded protein response

(2010) D. Thomas Rutkowski et al.   JOURNAL OF CELL BIOLOGY

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

A Crucial Role for RACK1 in the Regulation of Glucose-Stimulated IRE1  Activation in Pancreatic   Cells

(2010) Y. Qiu et al.   Science Signaling

Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction

(2009) Ji Luo et al.   CELL

The role of X-box binding protein-1 in tumorigenicity

(2009) A.N. Shajahan et al.   DRUG NEWS & PERSPECTIVES

Targeting the endoplasmic reticulum-stress response as an anticancer strategy

(2009) Sandra J.M. Healy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Critical Role of the Stress Chaperone GRP78/BiP in Tumor Proliferation, Survival, and Tumor Angiogenesis in Transgene-Induced Mammary Tumor Development

(2008) D. Dong et al.   CANCER RESEARCH

Derlin-1 Is Overexpressed on the Tumor Cell Surface and Enables Antibody-Mediated Tumor Targeting Therapy

(2008) Y. Ran et al.   CLINICAL CANCER RESEARCH

High-resolution genomic and expression analyses of copy number alterations in breast tumors

(2008) Peter M. Haverty et al.   GENES CHROMOSOMES & CANCER

Expression and splicing of the unfolded protein response gene XBP-1 are significantly associated with clinical outcome of endocrine-treated breast cancer

(2008) Michael P.A. Davies et al.   INTERNATIONAL JOURNAL OF CANCER

Stress Chaperone GRP78/BiP Confers Chemoresistance to Tumor-Associated Endothelial Cells

(2008) J. J. Virrey et al.   MOLECULAR CANCER RESEARCH

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE