Selective inhibition of the unfolded protein response: targeting catalytic sites for Schiff base modification
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Title
Selective inhibition of the unfolded protein response: targeting catalytic sites for Schiff base modification
Authors
Keywords
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Journal
Molecular BioSystems
Volume 9, Issue 10, Pages 2408
Publisher
Royal Society of Chemistry (RSC)
Online
2013-07-19
DOI
10.1039/c3mb70234k
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- (2012) C. L. Kriss et al. BLOOD
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- (2012) Matthew J. Harvey et al. DRUG DISCOVERY TODAY
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- (2011) Alexei V Korennykh et al. BMC BIOLOGY
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- Binding of Small-Molecule Ligands to Proteins: “What You See” Is Not Always “What You Get”
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