Increased PKC activity and altered GSK3β/NMDAR function drive behavior cycling in HINT1-deficient mice: bipolarity or opposing forces

Toward a Valid Animal Model of Bipolar Disorder: How the Research Domain Criteria Help Bridge the Clinical-Basic Science Divide

(2016) Victoria E. Cosgrove et al.   BIOLOGICAL PSYCHIATRY

Animal models of bipolar mania: The past, present and future

(2016) R.W. Logan et al.   NEUROSCIENCE

Hint1 knockout results in a compromised activation of protein kinase C gamma in the brain

(2015) Fan Zhang et al.   BRAIN RESEARCH

Three-Year, Naturalistic, Mirror-Image Assessment of Adding Memantine to the Treatment of 30 Treatment-Resistant Patients With Bipolar Disorder

(2015) Giulia Serra et al.   JOURNAL OF CLINICAL PSYCHIATRY

Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases

(2015) Eleonore Beurel et al.   PHARMACOLOGY & THERAPEUTICS

Hippocampal glutamatergic/NMDA receptor functioning in bipolar disorder: A study combining mismatch negativity and proton magnetic resonance spectroscopy

(2015) Kate M. Chitty et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Do antidepressants increase the risk of mania and bipolar disorder in people with depression? A retrospective electronic case register cohort study: Table 1

(2015) Rashmi Patel et al.   BMJ Open

Stressful life events in bipolar I and II disorder: Cause or consequence of mood symptoms?

(2014) M.A. Koenders et al.   JOURNAL OF AFFECTIVE DISORDERS

Partial effects of the protein kinase C inhibitor chelerythrine in a battery of tests for manic-like behavior in black Swiss mice

(2014) Haim Einat   Pharmacological Reports

A systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials of ketamine in the rapid treatment of major depressive episodes

(2014) A. McGirr et al.   PSYCHOLOGICAL MEDICINE

Ketamine administration in depressive disorders: a systematic review and meta-analysis

(2014) Guillaume Fond et al.   PSYCHOPHARMACOLOGY

Self-reported creativity in bipolar disorder: prevalence, types and associated outcomes in mania versus hypomania

(2013) Stacey McCraw et al.   JOURNAL OF AFFECTIVE DISORDERS

A review of ketamine in affective disorders: Current evidence of clinical efficacy, limitations of use and pre-clinical evidence on proposed mechanisms of action

(2013) Marie Naughton et al.   JOURNAL OF AFFECTIVE DISORDERS

Nitric Oxide and Zinc-Mediated Protein Assemblies Involved in Mu Opioid Receptor Signaling

(2013) María Rodríguez-Muñoz et al.   MOLECULAR NEUROBIOLOGY

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

(2013) Pierre Paoletti et al.   NATURE REVIEWS NEUROSCIENCE

HINT1 protein cooperates with cannabinoid 1 receptor to negatively regulate glutamate NMDA receptor activity

(2013) Ana Vicente-Sánchez et al.   Molecular Brain

GPCRs Promote the Release of Zinc Ions Mediated by nNOS/NO and the Redox Transducer RGSZ2 Protein

(2012) Pilar Sánchez-Blázquez et al.   ANTIOXIDANTS & REDOX SIGNALING

The Possible Involvement of NMDA Glutamate Receptor in the Etiopathogenesis of Bipolar Disorder

(2012) Konstantinos N. Fountoulakis   CURRENT PHARMACEUTICAL DESIGN

Targeting the Glutamatergic System to Treat Major Depressive Disorder

(2012) Daniel C. Mathews et al.   DRUGS

Triggers of mania and depression in young adults with bipolar disorder

(2012) Judith Proudfoot et al.   JOURNAL OF AFFECTIVE DISORDERS

Protein kinase C regulates mood-related behaviors and adult hippocampal cell proliferation in rats

(2012) Erika Abrial et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Increased anxiety-related behaviour in Hint1 knockout mice

(2011) Jeeva Varadarajulu et al.   BEHAVIOURAL BRAIN RESEARCH

Modeling mania: Further validation for Black Swiss mice as model animals

(2011) Chelsey Hannah-Poquette et al.   BEHAVIOURAL BRAIN RESEARCH

Behavioral differences in black Swiss mice from separate colonies

(2011) Jesse Juetten et al.   BEHAVIOURAL PHARMACOLOGY

β-catenin takes a HIT

(2011) Otmar Huber et al.   CELL CYCLE

Evidence for antimanic efficacy of glycogen synthase kinase-3 (GSK3) inhibitors in a strain-specific model of acute mania

(2011) Mikhail Kalinichev et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Annual Research Review: Transgenic mouse models of childhood-onset psychiatric disorders

(2011) Holly R. Robertson et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Un rôle pour la voie de signalisation Akt/GSK3 dans l’action des médicaments psychotropes et les maladies mentales

(2011) Thomas Del’Guidice et al.   M S-MEDECINE SCIENCES

Antidepressant phenotype by inhibiting the phospholipase Cβ1 – Protein kinase Cγ pathway in the forced swim test

(2011) Nicoletta Galeotti et al.   NEUROPHARMACOLOGY

Adenylyl cyclase-cyclicAMP signaling in mood disorders: Role of the crucial phosphorylating enzyme protein kinase A

(2011) Yogesh Dwivedi   Neuropsychiatric Disease and Treatment

Excellent school performance at age 16 and risk of adult bipolar disorder: national cohort study

(2010) James H. MacCabe et al.   BRITISH JOURNAL OF PSYCHIATRY

The histidine triad nucleotide-binding protein 1 supports mu-opioid receptor–glutamate NMDA receptor cross-regulation

(2010) María Rodríguez-Muñoz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The precipitants of manic/hypomanic episodes in the context of bipolar disorder: A review

(2010) Judith Proudfoot et al.   JOURNAL OF AFFECTIVE DISORDERS

Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level

(2009) Elisabeth Barbier et al.   BMC NEUROSCIENCE

Protein Kinase C Inhibitors

(2009) Carlos A. Zarate et al.   CNS DRUGS

Increased expression of the NR2A NMDA receptor subunit in the prefrontal cortex of rats reared in isolation

(2009) Julia J. Turnock-Jones et al.   SYNAPSE

Elevated levels of NR2A and PSD-95 in the lateral amygdala in depression

(2008) Beata Karolewicz et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Roles of NR2A and NR2B in the Development of Dendritic Arbor Morphology In Vivo

(2008) R. C. Ewald et al.   JOURNAL OF NEUROSCIENCE

Distribution and Expression of Protein Kinase C Interactive Protein (PKCI/HINT1) in Mouse Central Nervous System (CNS)

(2008) Qing Liu et al.   NEUROCHEMICAL RESEARCH