Autophagy down regulates pro-inflammatory mediators in BV2 microglial cells and rescues both LPS and alpha-synuclein induced neuronal cell death

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Transcriptional regulation of mammalian autophagy at a glance

(2016) Jens Füllgrabe et al.   JOURNAL OF CELL SCIENCE

The role of autophagy in modulation of neuroinflammation in microglia

(2016) P. Su et al.   NEUROSCIENCE

The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity

(2016) Timothy S. Jarvela et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Compromised autophagy and neurodegenerative diseases

(2015) Fiona M. Menzies et al.   NATURE REVIEWS NEUROSCIENCE

Neurodegenerative lysosomal disorders: A continuum from development to late age

(2014) Ralph A. Nixon et al.   Autophagy

Autophagy-dependent PELI3 degradation inhibits proinflammatory IL1B expression

(2014) Annika Klara Giegerich et al.   Autophagy

Toll-like receptors in central nervous system injury and disease: A focus on the spinal cord

(2014) Adee Heiman et al.   BRAIN BEHAVIOR AND IMMUNITY

Dynamic structural remodelling of microglia in health and disease: A review of the models, the signals and the mechanisms

(2014) F. Rohan Walker et al.   BRAIN BEHAVIOR AND IMMUNITY

Autophagy in the physiology and pathology of the central nervous system

(2014) V Nikoletopoulou et al.   CELL DEATH AND DIFFERENTIATION

microRNA-200b modulates microglia-mediated neuroinflammationviathe cJun/MAPK pathway

(2014) Shweta P. Jadhav et al.   JOURNAL OF NEUROCHEMISTRY

Neuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down-regulation of JNK1/2 and p38 MAPK activation

(2014) Mingjin Jiang et al.   Journal of Neuroinflammation

Trehalose Alleviates PC12 Neuronal Death Mediated by Lipopolysaccharide-Stimulated BV-2 Cells via Inhibiting Nuclear Transcription Factor NF-κB and AP-1 Activation

(2014) Qing He et al.   NEUROTOXICITY RESEARCH

Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy

(2014) Eszter Zavodszky et al.   Nature Communications

An Overview of Autophagy: Morphology, Mechanism, and Regulation

(2013) Katherine R. Parzych et al.   ANTIOXIDANTS & REDOX SIGNALING

Activation of Autophagy Pathway Suppresses the Expression of iNOS, IL6 and Cell Death of LPS-Stimulated Microglia Cells

(2013) Hye-Eun Han et al.   Biomolecules & Therapeutics

Autophagy in inflammation, infection, neurodegeneration and cancer

(2013) Daniela S. Arroyo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

IL-1β and TNF-α induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase

(2013) Ling Ye et al.   JOURNAL OF NEUROCHEMISTRY

TFEB-mediated autophagy rescues midbrain dopamine neurons from  -synuclein toxicity

(2013) M. Decressac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxic prefibrillar α-synuclein amyloid oligomers adopt a distinctive antiparallel β-sheet structure

(2012) María Soledad Celej et al.   BIOCHEMICAL JOURNAL

Autophagy in the Disorders of Central Nervous System: Vital and/or Fatal?

(2012) Pei Wang et al.   CNS Neuroscience & Therapeutics

Toll-like receptor 2 ligands promote microglial cell death by inducing autophagy

(2012) Daniela S. Arroyo et al.   FASEB JOURNAL

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

(2012) Chong-Shan Shi et al.   NATURE IMMUNOLOGY

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Cell death pathways and autophagy in the central nervous system and its involvement in neurodegeneration, immunity and central nervous system infection: to die or not to die - that is the question

(2011) A. Rosello et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation

(2011) James Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interleukin 4 induces the apoptosis of mouse microglial cells by a caspase-dependent mechanism

(2011) Javier A. Soria et al.   NEUROBIOLOGY OF DISEASE

A Mechanism for Synergy with Combined mTOR and PI3 Kinase Inhibitors

(2011) Shujie Yang et al.   PLoS One

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

α-Synuclein impairs macroautophagy: implications for Parkinson’s disease

(2010) Ashley R. Winslow et al.   JOURNAL OF CELL BIOLOGY

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Molecular pathogenesis of Parkinson disease: insights from genetic studies

(2009) Thomas Gasser   EXPERT REVIEWS IN MOLECULAR MEDICINE

Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

(2009) Yipeng Wang et al.   HUMAN MOLECULAR GENETICS

Autophagy in neurodegeneration and development

(2008) Ashley R. Winslow et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL