Targeted inhibition of Focal Adhesion Kinase Attenuates Cardiac Fibrosis and Preserves Heart Function in Adverse Cardiac Remodeling

Pharmacological Inhibition of Focal Adhesion Kinase Attenuates Cardiac Fibrosis in Mice Cardiac Fibroblast and Post-Myocardial-Infarction Models

(2015) Guang-Pu Fan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Revisiting Cardiac Cellular CompositionNovelty and Significance

(2015) Alexander R. Pinto et al.   CIRCULATION RESEARCH

Focal adhesion kinase and its role in skeletal muscle

(2015) Zachary A. Graham et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Adiponectin modulates focal adhesion disassembly in activated hepatic stellate cells: implication for reversing hepatic fibrosis

(2014) Pradeep Kumar et al.   FASEB JOURNAL

Mulberry Water Extracts Inhibit Atherosclerosis through Suppression of the Integrin-β3/Focal Adhesion Kinase Complex and Downregulation of Nuclear Factor κB Signaling in Vivo and in Vitro

(2014) Kuei-Chuan Chan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Resident fibroblast lineages mediate pressure overload–induced cardiac fibrosis

(2014) Thomas Moore-Morris et al.   JOURNAL OF CLINICAL INVESTIGATION

β-Arrestins regulate human cardiac fibroblast transformation and collagen synthesis in adverse ventricular remodeling

(2014) Jinju Li et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Laminin α2-Mediated Focal Adhesion Kinase Activation Triggers Alport Glomerular Pathogenesis

(2014) Duane Delimont et al.   PLoS One

FAK-Related Nonkinase Is a Multifunctional Negative Regulator of Pulmonary Fibrosis

(2013) Qiang Ding et al.   AMERICAN JOURNAL OF PATHOLOGY

Antifibrotic Effects of Focal Adhesion Kinase Inhibitor in Bleomycin-Induced Pulmonary Fibrosis in Mice

(2013) Katsuhiro Kinoshita et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Periodic Mechanical Stress Stimulates the FAK Mitogenic Signal in Rat Chondrocytes Through ERK1/2 Activity

(2013) Wenwei Liang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Focal adhesion kinase mediates atrial fibrosis via the AKT/S6K signaling pathway in chronic atrial fibrillation patients with rheumatic mitral valve disease

(2013) Peide Zhang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Adenoviral Gene Transfer of Endothelin-1 in the Lung Induces Pulmonary Fibrosis through the Activation of Focal Adhesion Kinase

(2012) David Lagares et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Targeting Focal Adhesion Kinase in Fibrotic Diseases

(2012) David Lagares et al.   BIODRUGS

Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury

(2011) Masanori Kawaguchi et al.   CIRCULATION

Focal adhesion kinase — The basis of local hypertrophic signaling domains

(2011) K.G. Franchini   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Role of lysyl oxidase in myocardial fibrosis: from basic science to clinical aspects

(2010) Begoña López et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Targeting Fibrosis for the Treatment of Heart Failure: A Role for Transforming Growth Factor-β

(2010) Amanda J Edgley et al.   Cardiovascular Therapeutics

Cardiac regulation by phosphoinositide 3-kinases and PTEN

(2009) G. Y. Oudit et al.   CARDIOVASCULAR RESEARCH

Cardiac Fibroblast

(2009) Colby A. Souders et al.   CIRCULATION RESEARCH

Cardiac Fibroblasts Regulate Myocardial Proliferation through β1 Integrin Signaling

(2009) Masaki Ieda et al.   DEVELOPMENTAL CELL

The extracellular matrix: At the center of it all

(2009) Stephanie L.K. Bowers et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Shp2 Negatively Regulates Growth in Cardiomyocytes by Controlling Focal Adhesion Kinase/Src and mTOR Pathways

(2008) Talita M. Marin et al.   CIRCULATION RESEARCH

Impact of Treatment on Myocardial Lysyl Oxidase Expression and Collagen Cross-Linking in Patients With Heart Failure

(2008) Begoña López et al.   HYPERTENSION

FAK regulates cardiomyocyte survival following ischemia/reperfusion

(2008) Zeenat S. Hakim et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY