Adenoviral Gene Transfer of Endothelin-1 in the Lung Induces Pulmonary Fibrosis through the Activation of Focal Adhesion Kinase

End of an ERA: Lessons from Negative Clinical Trials in Idiopathic Pulmonary Fibrosis

(2011) Paul W. Noble et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

BUILD-3: A Randomized, Controlled Trial of Bosentan in Idiopathic Pulmonary Fibrosis

(2011) Talmadge E. King et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation

(2011) David Lagares et al.   ARTHRITIS AND RHEUMATISM

Survivin expression induced by endothelin-1 promotes myofibroblast resistance to apoptosis

(2011) Jeffrey C. Horowitz et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The role of focal adhesion kinase catalytic activity on the proliferation and migration of squamous cell carcinoma cells

(2011) Alan Serrels et al.   INTERNATIONAL JOURNAL OF CANCER

Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant with Altering the Tumor Microenvironment

(2011) J. B. Stokes et al.   MOLECULAR CANCER THERAPEUTICS

Mechanical Tension Increases CCN2/CTGF Expression and Proliferation in Gingival Fibroblasts via a TGFβ-Dependent Mechanism

(2011) Fen Guo et al.   PLoS One

Endothelin 1 contributes to the effect of transforming growth factor β1 on wound repair and skin fibrosis

(2010) David Lagares et al.   ARTHRITIS AND RHEUMATISM

Sunitinib and PF-562,271 (FAK/Pyk2 inhibitor) effectively block growth and recovery of human hepatocellular carcinoma in a rat xenograft model

(2010) Cedo M Bagi et al.   CANCER BIOLOGY & THERAPY

Bioluminescent imaging study

(2010) Haihao Sun et al.   CANCER BIOLOGY & THERAPY

Expression of integrin  1 by fibroblasts is required for tissue repair in vivo

(2010) S. Liu et al.   JOURNAL OF CELL SCIENCE

Transforming growth factor-β-induced epithelial–mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression

(2010) M K Wendt et al.   ONCOGENE

CTGF enhances migration and MMP-13 up-regulation via αvβ3 integrin, FAK, ERK, and NF-κB-dependent pathway in human chondrosarcoma cells

(2009) Tzu-Wei Tan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Differential requirement for focal adhesion kinase signaling in cancer progression in the transgenic adenocarcinoma of mouse prostate model

(2009) J. K. Slack-Davis et al.   MOLECULAR CANCER THERAPEUTICS

Improvement of bleomycin-induced pulmonary hypertension and pulmonary fibrosis by the endothelin receptor antagonist Bosentan

(2009) Stephan Schroll et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Standardized quantification of pulmonary fibrosis in histological samples

(2008) Ralf-Harto Hübner et al.   BIOTECHNIQUES

Dual focal adhesion kinase/Pyk2 inhibitor has positive effects on bone tumors

(2008) Cedo M. Bagi et al.   CANCER

Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271

(2008) W. G. Roberts et al.   CANCER RESEARCH

Endothelin-1 promotes migration of endothelial cells through the activation of ARF6 and the regulation of FAK activity

(2008) Zeinab Daher et al.   CELLULAR SIGNALLING

Fibroblast adhesion results in the induction of a matrix remodeling gene expression program

(2008) L KENNEDY et al.   MATRIX BIOLOGY

The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?

(2007) Antje Moeller et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY