Paracrine Effects of Adipose-Derived Stem Cells on Matrix Stiffness-Induced Cardiac Myofibroblast Differentiation via Angiotensin II Type 1 Receptor and Smad7

Assessment of tumourigenic potential in long-term cryopreserved human adipose-derived stem cells

(2016) Kar Wey Yong et al.   Journal of Tissue Engineering and Regenerative Medicine

Mechanoregulation of cardiac myofibroblast differentiation: implications for cardiac fibrosis and therapy

(2015) Kar Wey Yong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Basic fibroblast growth factor-treated adipose tissue-derived mesenchymal stem cell infusion to ameliorate liver cirrhosis via paracrine hepatocyte growth factor

(2015) Wei-Ping Tang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Direct intercellular communications dominate the interaction between adipose-derived MSCs and myofibroblasts against cardiac fibrosis

(2015) Xiaokang Li et al.   Protein & Cell

In Situ Normoxia Enhances Survival and Proliferation Rate of Human Adipose Tissue-Derived Stromal Cells without Increasing the Risk of Tumourigenesis

(2015) Jane Ru Choi et al.   PLoS One

Phenotypic and Functional Characterization of Long-Term Cryopreserved Human Adipose-derived Stem Cells

(2015) Kar Wey Yong et al.   Scientific Reports

Impact of low oxygen tension on stemness, proliferation and differentiation potential of human adipose-derived stem cells

(2014) Jane Ru Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interaction between myofibroblasts and stem cells in the fibrotic heart: balancing between deterioration and regeneration

(2014) A. A. Ramkisoensing et al.   CARDIOVASCULAR RESEARCH

Does Transendocardial Injection of Mesenchymal Stem Cells Improve Myocardial Function Locally or Globally?

(2014) Viky Y. Suncion et al.   CIRCULATION RESEARCH

Autologous Mesenchymal Stem Cells Produce Concordant Improvements in Regional Function, Tissue Perfusion, and Fibrotic Burden When Administered to Patients Undergoing Coronary Artery Bypass Grafting

(2014) Vasileios Karantalis et al.   CIRCULATION RESEARCH

Injection of mesenchymal stromal cells into a mechanically stimulated in vitro model of cardiac fibrosis has paracrine effects on resident fibroblasts

(2014) Peter A. Galie et al.   CYTOTHERAPY

Interplay of matrix stiffness and protein tethering in stem cell differentiation

(2014) Jessica H. Wen et al.   NATURE MATERIALS

Extracellular matrix remodeling following myocardial infarction influences the therapeutic potential of mesenchymal stem cells

(2014) Kelly Sullivan et al.   Stem Cell Research & Therapy

Integrated Micro/Nanoengineered Functional Biomaterials for Cell Mechanics and Mechanobiology: A Materials Perspective

(2013) Yue Shao et al.   ADVANCED MATERIALS

Tissue mechanics and fibrosis

(2013) Rebecca G. Wells   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Reversible and irreversible differentiation of cardiac fibroblasts

(2013) Ronald B. Driesen et al.   CARDIOVASCULAR RESEARCH

Bone Marrow Progenitor Cell Therapy-Mediated Paracrine Regulation of Cardiac miRNA-155 Modulates Fibrotic Response in Diabetic Hearts

(2013) Raj Kishore et al.   PLoS One

Cardiac and Renal Protective Effects of Irbesartan via Peroxisome Proliferator‐Activated Receptorγ–Hepatocyte Growth Factor Pathway Independent of Angiotensin II Type 1a Receptor Blockade in Mouse Model of Salt‐Sensitive Hypertension

(2013) Hiroshi Kusunoki et al.   Journal of the American Heart Association

Regulation of Cardiac MicroRNAs by Bone Marrow Mononuclear Cell Therapy in Myocardial Infarction

(2012) Kazuma Iekushi et al.   CIRCULATION

Hepatocyte Growth Factor Reduces Cardiac Fibrosis by Inhibiting Endothelial-Mesenchymal Transition

(2012) Keita Okayama et al.   HYPERTENSION

Myofibroblasts in the Infarct Area: Concepts and Challenges

(2012) Evangelos P. Daskalopoulos et al.   MICROSCOPY AND MICROANALYSIS

Anchoring cell-fate cues

(2012) Ovijit Chaudhuri et al.   NATURE MATERIALS

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Myofibroblast-mediated mechanisms of pathological remodelling of the heart

(2012) Karl T. Weber et al.   Nature Reviews Cardiology

Concise Review: Adipose-Derived Stem Cells as a Novel Tool for Future Regenerative Medicine

(2012) Hiroshi Mizuno et al.   STEM CELLS

The Extracellular Matrix Modulates Fibroblast Phenotype and Function in the Infarcted Myocardium

(2012) Marcin Dobaczewski et al.   Journal of Cardiovascular Translational Research

Effects of mesenchymal stem cells on matrix metalloproteinase synthesis in cardiac fibroblasts

(2011) Yaping Wang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Interstitial fluid flow and cyclic strain differentially regulate cardiac fibroblast activation via AT1R and TGF-β1

(2011) P.A. Galie et al.   EXPERIMENTAL CELL RESEARCH

Hepatocyte Growth Factor Attenuates Transforming Growth Factor-β-Angiotensin II Crosstalk Through Inhibition of the PTEN/Akt Pathway

(2011) Kazuma Iekushi et al.   HYPERTENSION

Transplanted Human Amniotic Membrane-Derived Mesenchymal Stem Cells Ameliorate Carbon Tetrachloride-Induced Liver Cirrhosis in Mouse

(2011) DingGuo Zhang et al.   PLoS One

Potential Therapeutic Targets for Cardiac Fibrosis

(2010) Andrew Leask   CIRCULATION RESEARCH

Cardiac fibroblast to myofibroblast differentiation in vivo and in vitro: Expression of focal adhesion components in neonatal and adult rat ventricular myofibroblasts

(2010) Jon-Jon Santiago et al.   DEVELOPMENTAL DYNAMICS

Smad7 Blocks Transforming Growth Factor-β1–Induced Gingival Fibroblast–Myofibroblast Transition via Inhibitory Regulation of Smad2 and Connective Tissue Growth Factor

(2010) Lays M. Sobral et al.   JOURNAL OF PERIODONTOLOGY

Adipose Tissue Derived Stem Cells Secretome: Soluble Factors and Their Roles in Regenerative Medicine

(2010) Antonio J. Braga Osorio Gomes Salgado et al.   Current Stem Cell Research & Therapy

The therapeutic potential of human umbilical mesenchymal stem cells from Wharton's jelly in the treatment of rat liver fibrosis

(2009) Pei-Chun Tsai et al.   LIVER TRANSPLANTATION

Myocardial remodeling after infarction: the role of myofibroblasts

(2009) Susanne W. M. van den Borne et al.   Nature Reviews Cardiology

Mesenchymal Stem Cells Promote Matrix Metalloproteinase Secretion by Cardiac Fibroblasts and Reduce Cardiac Ventricular Fibrosis After Myocardial Infarction

(2009) C��line Mias et al.   STEM CELLS

Hepatocyte Growth Factor Inhibits Epithelial to Myofibroblast Transition in Lung Cells via Smad7

(2008) Manasi N. Shukla et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Neonatal and Adult Cardiovascular Pathophysiological Remodeling and Repair

(2008) Russell A. Norris et al.   Annals of the New York Academy of Sciences

Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activation

(2008) Noritaka Yasuda et al.   EMBO REPORTS

Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating

(2008) A. J. Engler et al.   JOURNAL OF CELL SCIENCE

Paracrine action mediate the antifibrotic effect of transplanted mesenchymal stem cells in a rat model of global heart failure

(2008) Lili Li et al.   MOLECULAR BIOLOGY REPORTS