In Situ Normoxia Enhances Survival and Proliferation Rate of Human Adipose Tissue-Derived Stromal Cells without Increasing the Risk of Tumourigenesis
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
In Situ Normoxia Enhances Survival and Proliferation Rate of Human Adipose Tissue-Derived Stromal Cells without Increasing the Risk of Tumourigenesis
Authors
Keywords
Oxygen, DNA damage, Tumor suppressor genes, Apoptosis, Mesenchymal stem cells, Gene expression, Telomere length, Cell differentiation
Journal
PLoS One
Volume 10, Issue 1, Pages e0115034
Publisher
Public Library of Science (PLoS)
Online
2015-01-24
DOI
10.1371/journal.pone.0115034
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Impact of low oxygen tension on stemness, proliferation and differentiation potential of human adipose-derived stem cells
- (2014) Jane Ru Choi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Concise Review: Evidence for CD34 as a Common Marker for Diverse Progenitors
- (2014) Laura E. Sidney et al. STEM CELLS
- Hypoxia-Induced Secretion of TGF-β1 in Mesenchymal Stem Cell Promotes Breast Cancer Cell Progression
- (2013) Shun-Pei Hung et al. CELL TRANSPLANTATION
- Risk of tumorigenicity in mesenchymal stromal cell–based therapies—Bridging scientific observations and regulatory viewpoints
- (2013) Lisbeth Barkholt et al. CYTOTHERAPY
- Low Oxygen Tension Maintains Multipotency, Whereas Normoxia Increases Differentiation of Mouse Bone Marrow Stromal Cells
- (2013) Ina Berniakovich et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Adipose stem cell therapy for soft tissue reconstruction
- (2013) J Peter Rubin et al. LANCET
- Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial
- (2013) Stig-Frederik Trojahn Kølle et al. LANCET
- VEGF-Mediated Proliferation of Human Adipose Tissue-Derived Stem Cells
- (2013) Guangfeng Chen et al. PLoS One
- A Stem Cell Perspective on Cellular Engineering
- (2013) S. Doulatov et al. SCIENCE
- Hypoxic Conditioning Enhances the Angiogenic Paracrine Activity of Human Adipose-Derived Stem Cells
- (2013) Sarah T. Hsiao et al. STEM CELLS AND DEVELOPMENT
- Pre-culturing human adipose tissue mesenchymal stem cells under hypoxia increases their adipogenic and osteogenic differentiation potentials
- (2012) M. G. Valorani et al. CELL PROLIFERATION
- The Stem Cell Niche in Regenerative Medicine
- (2012) Amy J. Wagers Cell Stem Cell
- Oxygen tension modifies the ‘stemness’ of human cord blood-derived stem cells
- (2012) Anja Buchheiser et al. CYTOTHERAPY
- Long-termin vitroexpansion of human adipose-derived stem cells showed low risk of tumourigenicity
- (2012) Wan Safwani Wan Kamarul Zaman et al. Journal of Tissue Engineering and Regenerative Medicine
- Overexpression of p53 protein in human tumors
- (2012) Keiji Inoue et al. Medical Molecular Morphology
- Hypoxia Promotes Osteogenesis but Suppresses Adipogenesis of Human Mesenchymal Stromal Cells in a Hypoxia-Inducible Factor-1 Dependent Manner
- (2012) Markus Wagegg et al. PLoS One
- Relearning the Lessons of Genomic Stability of Human Cells During Expansion in Culture: Implications for Clinical Research
- (2012) Darwin J. Prockop et al. STEM CELLS
- Oxygen tension regulates the osteogenic, chondrogenic and endochondral phenotype of bone marrow derived mesenchymal stem cells
- (2011) Eamon J. Sheehy et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Culture of human mesenchymal stem cells at low oxygen tension improves growth and genetic stability by activating glycolysis
- (2011) J C Estrada et al. CELL DEATH AND DIFFERENTIATION
- Large-Scale Analysis Reveals Acquisition of Lineage-Specific Chromosomal Aberrations in Human Adult Stem Cells
- (2011) Uri Ben-David et al. Cell Stem Cell
- Hypoxia Inhibits Osteogenesis in Human Mesenchymal Stem Cells through Direct Regulation of RUNX2 by TWIST
- (2011) Der-Chih Yang et al. PLoS One
- The Pivotal Role of Reactive Oxygen Species Generation in the Hypoxia-Induced Stimulation of Adipose-Derived Stem Cells
- (2011) Ji Hye Kim et al. STEM CELLS AND DEVELOPMENT
- Hypoxic Preconditioning Enhances Survival of Human Adipose-Derived Stem Cells and Conditions Endothelial Cells In Vitro
- (2011) Samantha Licy Stubbs et al. STEM CELLS AND DEVELOPMENT
- Hypoxia inhibits senescence and maintains mesenchymal stem cell properties through down-regulation of E2A-p21 by HIF-TWIST
- (2010) C.-C. Tsai et al. BLOOD
- Hypoxia increases Sca-1/CD44 co-expression in murine mesenchymal stem cells and enhances their adipogenic differentiation potential
- (2010) M. G. Valorani et al. CELL AND TISSUE RESEARCH
- Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche
- (2010) Ahmed Mohyeldin et al. Cell Stem Cell
- Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition
- (2010) Kenichi Tamama et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Mesenchymal stem cells cultured under hypoxia escape from senescence via down-regulation of p16 and extracellular signal regulated kinase
- (2009) Yonghui Jin et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Nuclear accumulation and activation of p53 in embryonic stem cells after DNA damage
- (2009) Valeriya Solozobova et al. BMC CELL BIOLOGY
- Long-term Cultures of Bone Marrow–Derived Human Mesenchymal Stem Cells Frequently Undergo Spontaneous Malignant Transformation
- (2009) Gro Vatne Røsland et al. CANCER RESEARCH
- Telomeres and telomerase in cancer
- (2009) S. E. Artandi et al. CARCINOGENESIS
- Transcriptional signature of human adipose tissue-derived stem cells (hASCs) preconditioned for chondrogenesis in hypoxic conditions
- (2009) L. Pilgaard et al. EXPERIMENTAL CELL RESEARCH
- Responses of adipose-derived stem cells during hypoxia: enhanced skin-regenerative potential
- (2009) Hyung-Min Chung et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- FGF2 stimulates the proliferation of human mesenchymal stem cells through the transient activation of JNK signaling
- (2009) Hee-Jin Ahn et al. FEBS LETTERS
- Hypoxia or in situ normoxia: The stem cell paradigm
- (2009) Zoran Ivanovic JOURNAL OF CELLULAR PHYSIOLOGY
- A Complex Role for FGF-2 in Self-Renewal, Survival, and Adhesion of Human Embryonic Stem Cells
- (2009) Livia Eiselleova et al. STEM CELLS
- Hypoxia-enhanced wound-healing function of adipose-derived stem cells: Increase in stem cell proliferation and up-regulation of VEGF and bFGF
- (2009) Eun Young Lee et al. WOUND REPAIR AND REGENERATION
- Human mesenchymal stem cells stimulated by TNF-α, LPS, or hypoxia produce growth factors by an NFκB- but not JNK-dependent mechanism
- (2008) Paul R. Crisostomo et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Reduced Adipose Tissue Oxygenation in Human Obesity: Evidence for Rarefaction, Macrophage Chemotaxis, and Inflammation Without an Angiogenic Response
- (2008) M. Pasarica et al. DIABETES
- A Reservoir of Brown Adipocyte Progenitors in Human Skeletal Muscle
- (2008) Mihaela Crisan et al. STEM CELLS
- IFATS Collection: Adipose Stromal Cells Adopt a Proangiogenic Phenotype Under the Influence of Hypoxia
- (2008) Hariharan Thangarajah et al. STEM CELLS
- A Population of Multipotent CD34-Positive Adipose Stromal Cells Share Pericyte and Mesenchymal Surface Markers, Reside in a Periendothelial Location, and Stabilize Endothelial Networks
- (2007) Dmitry O. Traktuev et al. CIRCULATION RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started