Metformin Uniquely Prevents Thrombosis by Inhibiting Platelet Activation and mtDNA Release
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Metformin Uniquely Prevents Thrombosis by Inhibiting Platelet Activation and mtDNA Release
Authors
Keywords
-
Journal
Scientific Reports
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-11-02
DOI
10.1038/srep36222
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart FailureCLINICAL PERSPECTIVE
- (2016) Akihiro Shirakabe et al. CIRCULATION
- Autophagy is induced upon platelet activation and is essential for hemostasis and thrombosis
- (2015) M. M. Ouseph et al. BLOOD
- Nucleotide-Binding Oligomerization Domain 2 Receptor Is Expressed in Platelets and Enhances Platelet Activation and ThrombosisCLINICAL PERSPECTIVE
- (2015) Si Zhang et al. CIRCULATION
- Kaempferol suppresses collagen-induced platelet activation by inhibiting NADPH oxidase and protecting SHP-2 from oxidative inactivation
- (2015) Su Bin Wang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Variation of perioperative plasma mitochondrial DNA correlate with peak inflammatory cytokines caused by cardiac surgery with cardiopulmonary bypass
- (2015) Chaoyi Qin et al. Journal of Cardiothoracic Surgery
- Structure-Based Design of Macrocyclic Coagulation Factor VIIa Inhibitors
- (2015) E. Scott Priestley et al. JOURNAL OF MEDICINAL CHEMISTRY
- Mitochondrial DNA stress primes the antiviral innate immune response
- (2015) A. Phillip West et al. NATURE
- Metformin reduces hyper-reactivity of platelets from patients with polycystic ovary syndrome by improving mitochondrial integrity
- (2015) Amro Elgheznawy et al. THROMBOSIS AND HAEMOSTASIS
- Metformin use in patients with type 2 diabetes mellitus is associated with reduced risk of deep vein thrombosis: a non-randomized, pair-matched cohort study
- (2015) Dai-Yin Lu et al. BMC Cardiovascular Disorders
- Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial complex I inhibition
- (2014) S. Piel et al. Acta Physiologica
- Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria
- (2014) Hannah R. Bridges et al. BIOCHEMICAL JOURNAL
- Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation
- (2014) L. H. Boudreau et al. BLOOD
- Platelet bioenergetic screen in sickle cell patients reveals mitochondrial complex V inhibition, which contributes to platelet activation
- (2014) N. Cardenes et al. BLOOD
- Risk of venous and arterial thrombotic events in patients diagnosed with superficial vein thrombosis: a nationwide cohort study
- (2014) S. C. Cannegieter et al. BLOOD
- Aldose Reductase–Mediated Phosphorylation of p53 Leads to Mitochondrial Dysfunction and Damage in Diabetic Platelets
- (2014) Wai Ho Tang et al. CIRCULATION
- Synthesis and identification of chiral aminomethylpiperidine carboxamides as inhibitor of collagen induced platelet activation
- (2014) K.S. Anil Kumar et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- MPV may reflect subcinical platelet activation in diabetic patients with and without diabetic retinopathy
- (2014) M Citirik et al. EYE
- Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
- (2014) Anila K. Madiraju et al. NATURE
- Circulating Mitochondrial DNA in Patients in the ICU as a Marker of Mortality: Derivation and Validation
- (2014) Kiichi Nakahira et al. PLOS MEDICINE
- Hydrogen Peroxide Promotes Aging-Related Platelet Hyperactivation and Thrombosis
- (2013) Sanjana Dayal et al. CIRCULATION
- Dengue induces platelet activation, mitochondrial dysfunction and cell death through mechanisms that involve DC-SIGN and caspases
- (2013) E. D. Hottz et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Ginsenoside Rg1 inhibits platelet activation and arterial thrombosis
- (2013) Qi Zhou et al. THROMBOSIS RESEARCH
- Inhibiting platelet-stimulated blood coagulation by inhibition of mitochondrial respiration
- (2012) C. J. Barile et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets
- (2011) S. M. Schoenwaelder et al. BLOOD
- Diabetes mellitus and thrombosis
- (2011) Natale Vazzana et al. THROMBOSIS RESEARCH
- Metformin Use and Mortality Among Patients With Diabetes and AtherothrombosisMetformin Use With Diabetes and Atherothrombosis
- (2010) Ronan Roussel ARCHIVES OF INTERNAL MEDICINE
- von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models
- (2010) A. Brill et al. BLOOD
- Anti-thrombosis effect of diosgenin extract from Dioscorea zingiberensis C.H. Wright in vitro and in vivo
- (2010) Guohua Gong et al. PHYTOMEDICINE
- Caspase-7 deficiency protects from endotoxin-induced lymphocyte apoptosis and improves survival
- (2009) M. Lamkanfi et al. BLOOD
- Platelet Dense-Granule Secretion Plays a Critical Role in Thrombosis and Subsequent Vascular Remodeling in Atherosclerotic Mice
- (2009) Sarah M. King et al. CIRCULATION
- Trivalent methylated arsenical-induced phosphatidylserine exposure and apoptosis in platelets may lead to increased thrombus formation
- (2009) Ok-Nam Bae et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- Triggers, targets and treatments for thrombosis
- (2008) Nigel Mackman NATURE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now