Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial complex I inhibition

Methylene blue used in the treatment of refractory shock resulting from drug poisoning

(2013) J. Fisher et al.   CLINICAL TOXICOLOGY

Metformin overdose-induced hypoglycemia in the absence of other antidiabetic drugs

(2013) S. A. Al-Abri et al.   CLINICAL TOXICOLOGY

Mitochondrial respiration in human viable platelets—Methodology and influence of gender, age and storage

(2012) Fredrik Sjövall et al.   MITOCHONDRION

Clinical Pharmacokinetics of Metformin

(2011) Garry G. Graham et al.   CLINICAL PHARMACOKINETICS

Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration

(2011) S. Larsen et al.   DIABETOLOGIA

Alternative Mitochondrial Electron Transfer as a Novel Strategy for Neuroprotection

(2011) Yi Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lactic Acidosis Induced by Metformin

(2010) Jean-Daniel Lalau   DRUG SAFETY

Evaluation of three portable blood lactate analysers: Lactate Pro, Lactate Scout and Lactate Plus

(2010) Rebecca K. Tanner et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Metformin selectively attenuates mitochondrial H2O2 emission without affecting respiratory capacity in skeletal muscle of obese rats

(2010) Daniel A. Kane et al.   FREE RADICAL BIOLOGY AND MEDICINE

A comparison of uptake of metformin and phenformin mediated by hOCT1 in human hepatocytes

(2009) Yoshihisa Sogame et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro

(2008) James A. Dykens et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic β-cells through restoration of mitochondrial electron transfer

(2007) S A Hinke et al.   BRITISH JOURNAL OF PHARMACOLOGY