Hepatitis C Virus Infection of Cultured Human Hepatoma Cells Causes Apoptosis and Pyroptosis in Both Infected and Bystander Cells

NLRP3 regulates a non-canonical platform for caspase-8 activation during epithelial cell apoptosis

(2016) H Chung et al.   CELL DEATH AND DIFFERENTIATION

The Inflammasome Adaptor ASC Induces Procaspase-8 Death Effector Domain Filaments

(2015) Parimala R. Vajjhala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling

(2015) Christina Antonopoulos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heatstroke induces liver injury via IL-1β and HMGB1-induced pyroptosis

(2015) Yan Geng et al.   JOURNAL OF HEPATOLOGY

InternalizedCryptococcus neoformansActivates the Canonical Caspase-1 and the Noncanonical Caspase-8 Inflammasomes

(2015) Mingkuan Chen et al.   JOURNAL OF IMMUNOLOGY

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

ER stress induces NLRP3 inflammasome activation and hepatocyte death

(2015) C Lebeaupin et al.   Cell Death & Disease

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Staying Alive: Cell Death in Antiviral Immunity

(2014) Jason W. Upton et al.   MOLECULAR CELL

Not-so-innocent bystanders

(2014) Andrea L. Cox et al.   NATURE

HCV Genomic RNA Activates the NLRP3 Inflammasome in Human Myeloid Cells

(2014) Wei Chen et al.   PLoS One

Virus associated malignancies: The role of viral hepatitis in hepatocellular carcinoma

(2014) Amir Shlomai et al.   SEMINARS IN CANCER BIOLOGY

Many players in BCL-2 family affairs

(2014) Tudor Moldoveanu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Hepatic inflammation and progressive liver fibrosis in chronic liver disease

(2014) Albert J Czaja   WORLD JOURNAL OF GASTROENTEROLOGY

The chains of death

(2013) Kolja Schleich et al.   CELL CYCLE

AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC

(2013) V Sagulenko et al.   CELL DEATH AND DIFFERENTIATION

Hepatitis C Virus Induces Interleukin-1  (IL-1 )/IL-18 in Circulatory and Resident Liver Macrophages

(2013) S. Shrivastava et al.   JOURNAL OF VIROLOGY

IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease

(2013) Amina A. Negash et al.   PLoS Pathogens

Sterile Inflammation in the Liver

(2012) Paul Kubes et al.   GASTROENTEROLOGY

Global epidemiology of hepatitis C virus infection: New estimates of age-specific antibody to HCV seroprevalence

(2012) Khayriyyah Mohd Hanafiah et al.   HEPATOLOGY

HIV-1 Induced Bystander Apoptosis

(2012) Himanshu Garg et al.   Viruses-Basel

Hepatitis C Virus Infection Causes Cell Cycle Arrest at the Level of Initiation of Mitosis

(2011) R. P. Kannan et al.   JOURNAL OF VIROLOGY

A Genetic Interaction between the Core and NS3 Proteins of Hepatitis C Virus Is Essential for Production of Infectious Virus

(2011) D. M. Jones et al.   JOURNAL OF VIROLOGY

NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma

(2011) Tom Luedde et al.   Nature Reviews Gastroenterology & Hepatology

Current status of novel antifibrotic therapies in patients with chronic liver disease

(2011) Michal Cohen-Naftaly et al.   Therapeutic Advances in Gastroenterology

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Secondary necrosis: The natural outcome of the complete apoptotic program

(2010) Manuel T. Silva   FEBS LETTERS

Epithelial–mesenchymal transition in hepatocellular carcinoma

(2009) Franziska van Zijl et al.   Future Oncology

Incidence of hepatocellular carcinoma in hepatitis C carriers with normal alanine aminotransferase levels

(2009) Takashi Kumada et al.   JOURNAL OF HEPATOLOGY

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Genomic Analysis Reveals a Potential Role for Cell Cycle Perturbation in HCV-Mediated Apoptosis of Cultured Hepatocytes

(2009) Kathie-Anne Walters et al.   PLoS Pathogens

HCV Induces Oxidative and ER Stress, and Sensitizes Infected Cells to Apoptosis in SCID/Alb-uPA Mice

(2009) Michael A. Joyce et al.   PLoS Pathogens

Altered expression of cell cycle and apoptotic proteins in chronic hepatitis C virus infection

(2008) Saira Sarfraz et al.   BMC MICROBIOLOGY

Serum aminotransferase level and the risk of hepatocellular carcinoma: a population-based cohort study in Japan

(2008) Seiji Ishiguro et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus

(2008) R. S. Russell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms

(2008) S. L. Fink et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intragenotypic JFH1 based recombinant hepatitis C virus produces high levels of infectious particles but causes increased cell death

(2008) Guaniri Mateu et al.   VIROLOGY

Development of plaque assays for hepatitis C virus-JFH1 strain and isolation of mutants with enhanced cytopathogenicity and replication capacity

(2007) Yuko Sekine-Osajima et al.   VIROLOGY