Common variants in the PARL and PINK1 genes increase the risk to leprosy in Han Chinese from South China

Genetic variants of the MAVS, MITA and MFN2 genes are not associated with leprosy in Han Chinese from Southwest China

(2016) Dong Wang et al.   INFECTION GENETICS AND EVOLUTION

Integrative analyses of leprosy susceptibility genes indicate a common autoimmune profile

(2016) Deng-Feng Zhang et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Mutation analyses and association studies to assess the role of the presenilin-associated rhomboid-like gene in Parkinson's disease

(2016) Richard Wüst et al.   NEUROBIOLOGY OF AGING

A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy

(2016) Vinicius M. Fava et al.   PLoS Neglected Tropical Diseases

Intramembrane protease PARL defines a negative regulator of PINK1- and PARK2/Parkin-dependent mitophagy

(2015) Cathrin Meissner et al.   Autophagy

Common variants of OPA1 conferring genetic susceptibility to leprosy in Han Chinese from Southwest China

(2015) Yang-Lin Xiang et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

PLD3 in Alzheimer’s Disease: a Modest Effect as Revealed by Updated Association and Expression Analyses

(2015) Deng-Feng Zhang et al.   MOLECULAR NEUROBIOLOGY

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

BioGPS: building your own mash-up of gene annotations and expression profiles

(2015) Chunlei Wu et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Screening of mRNA Expression in Leprosy Patients

(2015) Andrea de Faria F. Belone et al.   Frontiers in Genetics

Association of the LRRK2 genetic polymorphisms with leprosy in Han Chinese from Southwest China

(2014) D Wang et al.   GENES AND IMMUNITY

Common variants of the PINK1 and PARL genes do not confer genetic susceptibility to schizophrenia in Han Chinese

(2014) Xiao Li et al.   MOLECULAR GENETICS AND GENOMICS

PARK2 and proinflammatory/anti-inflammatory cytokine gene interactions contribute to the susceptibility to leprosy: a case–control study of North Indian population

(2014) Rupali Chopra et al.   BMJ Open

The effects of genetic variation on gene expression dynamics during development

(2013) Mirko Francesconi et al.   NATURE

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Gene Expression Profiling Specifies Chemokine, Mitochondrial and Lipid Metabolism Signatures in Leprosy

(2013) Luana Tatiana Albuquerque Guerreiro et al.   PLoS One

LRRK2 and RIPK2 Variants in the NOD 2-Mediated Signaling Pathway Are Associated with Susceptibility to Mycobacterium leprae in Indian Populations

(2013) Patrick Marcinek et al.   PLoS One

Mapping of PARK2 and PACRG Overlapping Regulatory Region Reveals LD Structure and Functional Variants in Association with Leprosy in Unrelated Indian Population Groups

(2013) Rupali Chopra et al.   PLoS Genetics

The antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shock

(2012) Luiza K. Sanjuán Szklarz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

Genetic variants of the MRC1 gene and the IFNG gene are associated with leprosy in Han Chinese from Southwest China

(2012) Dong Wang et al.   HUMAN GENETICS

Mitochondrial DNA Copy Number, but Not Haplogroup, Confers a Genetic Susceptibility to Leprosy in Han Chinese from Southwest China

(2012) Dong Wang et al.   PLoS One

Mitochondria and autophagy: Critical interplay between the two homeostats

(2011) Koji Okamoto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Association study of the single nucleotide polymorphisms of PARK2 and PACRG with leprosy susceptibility in Chinese population

(2011) Jinghui Li et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Regulation of Skeletal Muscle Oxidative Capacity and Insulin Signaling by the Mitochondrial Rhomboid Protease PARL

(2010) Anthony E. Civitarese et al.   Cell Metabolism

No association between the SNPs (rs3749446 and rs1402000) in the PARL gene and LHON in Chinese patients with m.11778G>A

(2010) A-Mei Zhang et al.   HUMAN GENETICS

Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand

(2010) Nopasak Phasukkijwatana et al.   HUMAN GENETICS

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

(2010) Seok Min Jin et al.   JOURNAL OF CELL BIOLOGY

Leprosy as a genetic disease

(2010) Andrea Alter et al.   MAMMALIAN GENOME

Leprosy and the Human Genome

(2010) E. A. Misch et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

(2010) David Warde-Farley et al.   NUCLEIC ACIDS RESEARCH

Genetic variation in PARL influences mitochondrial content

(2009) Joanne E. Curran et al.   HUMAN GENETICS

Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF- B signaling

(2009) D. Sha et al.   HUMAN MOLECULAR GENETICS

Comparative genomic and phylogeographic analysis of Mycobacterium leprae

(2009) Marc Monot et al.   NATURE GENETICS

Genomewide Association Study of Leprosy

(2009) Fu-Ren Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ancient Skeletal Evidence for Leprosy in India (2000 B.C.)

(2009) Gwen Robbins et al.   PLoS One

Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress

(2008) C. A. Gautier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA