Fibroblast growth factor 21 reflects liver fat accumulation and dysregulation of signalling pathways in the liver of C57BL/6J mice

Diet, weight loss, and liver health in nonalcoholic fatty liver disease: Pathophysiology, evidence, and practice

(2016) Giulio Marchesini et al.   HEPATOLOGY

Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease

(2016) Tuulia Hyötyläinen et al.   Nature Communications

Adaptation of Hepatic Mitochondrial Function in Humans with Non-Alcoholic Fatty Liver Is Lost in Steatohepatitis

(2015) Chrysi Koliaki et al.   Cell Metabolism

A weekly alternating diet between caloric restriction and medium fat protects the liver from fatty liver development in middle-aged C57BL/6J mice

(2015) Fenni Rusli et al.   MOLECULAR NUTRITION & FOOD RESEARCH

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Epidemiology and Natural History of Nonalcoholic Fatty Liver Disease

(2015) Sanjaya Satapathy et al.   SEMINARS IN LIVER DISEASE

FGF21 Revolutions: Recent Advances Illuminating FGF21 Biology and Medicinal Properties

(2015) Alexei Kharitonenkov et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The genetic architecture of NAFLD among inbred strains of mice

(2015) Simon T Hui et al.   eLife

Behavioural changes are a major contributing factor in the reduction of sarcopenia in caloric-restricted ageing mice

(2015) Klaske van Norren et al.   Journal of Cachexia Sarcopenia and Muscle

Fibroblast growth factor 21 participates in adaptation to endoplasmic reticulum stress and attenuates obesity-induced hepatic metabolic stress

(2014) Seong Hun Kim et al.   DIABETOLOGIA

Phenotypic flexibility as key factor in the human nutrition and health relationship

(2014) Ben van Ommen et al.   Genes and Nutrition

Fibroblast Growth Factor 21 Is Regulated by the IRE1α-XBP1 Branch of the Unfolded Protein Response and Counteracts Endoplasmic Reticulum Stress-induced Hepatic Steatosis

(2014) Shan Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sexually dimorphic characteristics of the small intestine and colon of prepubescent C57BL/6 mice

(2014) Wilma T Steegenga et al.   Biology of Sex Differences

Prevalence of Nonalcoholic Fatty Liver Disease in the United States: The Third National Health and Nutrition Examination Survey, 1988–1994

(2013) Mariana Lazo et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress

(2013) Chaofeng Yang et al.   BMC GASTROENTEROLOGY

Hepatocellular Benign Tumors—From Molecular Classification to Personalized Clinical Care

(2013) Jean–Charles Nault et al.   GASTROENTEROLOGY

Epidemiology and risk factors of nonalcoholic fatty liver disease (NAFLD)

(2013) Ajay Duseja et al.   Hepatology International

Molecular MRI of collagen to diagnose and stage liver fibrosis

(2013) Bryan C. Fuchs et al.   JOURNAL OF HEPATOLOGY

Accuracy of prediction scores and novel biomarkers for predicting nonalcoholic fatty liver disease in obese children

(2013) Bart G.P. Koot et al.   Obesity

Association between Serum Atypical Fibroblast Growth Factors 21 and 19 and Pediatric Nonalcoholic Fatty Liver Disease

(2013) Anna Alisi et al.   PLoS One

Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

(2013) Huating Li et al.   Frontiers of Medicine

The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology and the American Gastroenterological Association

(2012) Naga Chalasani et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Fibroblast growth factor 21 is induced by endoplasmic reticulum stress

(2012) Frank G. Schaap et al.   BIOCHIMIE

βKlotho Is Required for Fibroblast Growth Factor 21 Effects on Growth and Metabolism

(2012) Xunshan Ding et al.   Cell Metabolism

Fibroblast Growth Factor 21 (FGF-21) and Its Relation to Obesity, Metabolic Syndrome, and Nonalcoholic Fatty Liver in Children: A Longitudinal Analysis

(2012) Thomas Reinehr et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Non-invasive diagnosis of non-alcoholic steatohepatitis by combined serum biomarkers

(2012) Jiayun Shen et al.   JOURNAL OF HEPATOLOGY

Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver

(2012) Santhosh Satapati et al.   JOURNAL OF LIPID RESEARCH

Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease

(2011) Nishanth E. Sunny et al.   Cell Metabolism

Circulating Fibroblast Growth Factor 21 Levels Are Closely Associated with Hepatic Fat Content: A Cross-Sectional Study

(2011) Hongmei Yan et al.   PLoS One

Adipose Tissue Dysfunction Signals Progression of Hepatic Steatosis Towards Nonalcoholic Steatohepatitis in C57Bl/6 Mice

(2010) C. Duval et al.   DIABETES

Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State

(2010) f. M. Fisher et al.   DIABETES

Epidemiology of Non-Alcoholic Fatty Liver Disease

(2010) Stefano Bellentani et al.   DIGESTIVE DISEASES

Increased serum FGF21 levels in patients with nonalcoholic fatty liver disease

(2010) Yusuf Yilmaz et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Increased Fibroblast Growth Factor 21 in Obesity and Nonalcoholic Fatty Liver Disease

(2010) Jody Dushay et al.   GASTROENTEROLOGY

Non-alcoholic fatty liver disease as a risk factor for hepatocellular carcinoma: mechanisms and implications

(2010) F. Stickel et al.   GUT

Fibroblast growth factor 21 levels are increased in nonalcoholic fatty liver disease patients and are correlated with hepatic triglyceride

(2010) Huating Li et al.   JOURNAL OF HEPATOLOGY

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Serum FGF21 Levels Are Increased in Obesity and Are Independently Associated With the Metabolic Syndrome in Humans

(2008) X. Zhang et al.   DIABETES

Adipose Fibroblast Growth Factor 21 Is Up-Regulated by Peroxisome Proliferator-Activated Receptor   and Altered Metabolic States

(2008) E. S. Muise et al.   MOLECULAR PHARMACOLOGY

FGF-21/FGF-21 receptor interaction and activation is determined by βKlotho

(2007) Alexei Kharitonenkov et al.   JOURNAL OF CELLULAR PHYSIOLOGY