Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects
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Title
Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects
Authors
Keywords
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Journal
Scientific Reports
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-09-19
DOI
10.1038/srep33377
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Note: Only part of the references are listed.- Common pitfalls of stem cell differentiation: a guide to improving protocols for neurodegenerative disease models and research
- (2016) Martin Engel et al. CELLULAR AND MOLECULAR LIFE SCIENCES
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- (2015) Consiglia Pacelli et al. CURRENT BIOLOGY
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- (2015) Mattia Volta et al. LANCET NEUROLOGY
- Oxidative stress and Parkinson’s disease
- (2015) Javier Blesa et al. Frontiers in Neuroanatomy
- Neurite Aggregation and Calcium Dysfunction in iPSC-Derived Sensory Neurons with Parkinson’s Disease-Related LRRK2 G2019S Mutation
- (2015) Andrew J. Schwab et al. Stem Cell Reports
- The prevalence of Parkinson's disease: A systematic review and meta-analysis
- (2014) Tamara Pringsheim et al. MOVEMENT DISORDERS
- Physiological Characterisation of Human iPS-Derived Dopaminergic Neurons
- (2014) Elizabeth M. Hartfield et al. PLoS One
- Genetics and genomics of Parkinson’s disease
- (2014) Michelle K Lin et al. Genome Medicine
- Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression
- (2013) Peter Reinhardt et al. Cell Stem Cell
- Advances in the genetics of Parkinson disease
- (2013) Joanne Trinh et al. Nature Reviews Neurology
- The energy cost of action potential propagation in dopamine neurons: clues to susceptibility in Parkinson's disease
- (2013) Eleftheria K. Pissadaki et al. Frontiers in Computational Neuroscience
- Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease
- (2012) Adriana Sánchez-Danés et al. EMBO Molecular Medicine
- Living on the edge with too many mouths to feed: Why dopamine neurons die
- (2012) J. Paul Bolam et al. MOVEMENT DISORDERS
- LRRK2 Phosphorylates Tubulin-Associated Tau but Not the Free Molecule: LRRK2-Mediated Regulation of the Tau-Tubulin Association and Neurite Outgrowth
- (2012) Fumitaka Kawakami et al. PLoS One
- Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson's Disease
- (2012) O. Cooper et al. Science Translational Medicine
- Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case–control study
- (2011) Owen A Ross et al. LANCET NEUROLOGY
- Modelling schizophrenia using human induced pluripotent stem cells
- (2011) Kristen J. Brennand et al. NATURE
- Plus-End-Tracking Proteins and Their Interactions at Microtubule Ends
- (2010) Niels Galjart CURRENT BIOLOGY
- Protein misfolding disorders and macroautophagy
- (2010) Fiona M Menzies et al. CURRENT OPINION IN CELL BIOLOGY
- Parkinson Disease: A Role for Autophagy?
- (2010) Qian Yang et al. NEUROSCIENTIST
- Foxa2 and Nurr1 Synergistically Yield A9 Nigral Dopamine Neurons Exhibiting Improved Differentiation, Function and Cell Survival
- (2010) Hyun-Seob Lee et al. STEM CELLS
- The Parkinson’s disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites
- (2009) Elisa Greggio et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
- (2009) Frank Soldner et al. CELL
- Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon
- (2009) Tomoya Nakatani et al. DEVELOPMENTAL BIOLOGY
- Parkinson's disease: from monogenic forms to genetic susceptibility factors
- (2009) S. Lesage et al. HUMAN MOLECULAR GENETICS
- Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability - a point of convergence in Parkinsonian neurodegeneration?
- (2009) Frank Gillardon JOURNAL OF NEUROCHEMISTRY
- Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis
- (2009) L. Parisiadou et al. JOURNAL OF NEUROSCIENCE
- Single Nigrostriatal Dopaminergic Neurons Form Widely Spread and Highly Dense Axonal Arborizations in the Neostriatum
- (2009) W. Matsuda et al. JOURNAL OF NEUROSCIENCE
- Disease-Specific Induced Pluripotent Stem Cells
- (2008) In-Hyun Park et al. CELL
- The Parkinson Disease-associated Leucine-rich Repeat Kinase 2 (LRRK2) Is a Dimer That Undergoes Intramolecular Autophosphorylation
- (2008) Elisa Greggio et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells
- (2008) Edward D. Plowey et al. JOURNAL OF NEUROCHEMISTRY
- The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules
- (2008) Payal N. Gandhi et al. JOURNAL OF NEUROSCIENCE RESEARCH
- LRRK2 Gly2019Ser penetrance in Arab–Berber patients from Tunisia: a case-control genetic study
- (2008) Mary M Hulihan et al. LANCET NEUROLOGY
- Mitochondria in the aetiology and pathogenesis of Parkinson's disease
- (2008) Anthony HV Schapira LANCET NEUROLOGY
- Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study
- (2008) Daniel G Healy et al. LANCET NEUROLOGY
- Progress in Parkinson's disease—Where do we stand?
- (2008) André Toulouse et al. PROGRESS IN NEUROBIOLOGY
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