Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects
出版年份 2016 全文链接
标题
Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects
作者
关键词
-
出版物
Scientific Reports
Volume 6, Issue 1, Pages -
出版商
Springer Nature
发表日期
2016-09-19
DOI
10.1038/srep33377
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Common pitfalls of stem cell differentiation: a guide to improving protocols for neurodegenerative disease models and research
- (2016) Martin Engel et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Elevated Mitochondrial Bioenergetics and Axonal Arborization Size Are Key Contributors to the Vulnerability of Dopamine Neurons
- (2015) Consiglia Pacelli et al. CURRENT BIOLOGY
- Insights from late-onset familial parkinsonism on the pathogenesis of idiopathic Parkinson's disease
- (2015) Mattia Volta et al. LANCET NEUROLOGY
- Oxidative stress and Parkinson’s disease
- (2015) Javier Blesa et al. Frontiers in Neuroanatomy
- Neurite Aggregation and Calcium Dysfunction in iPSC-Derived Sensory Neurons with Parkinson’s Disease-Related LRRK2 G2019S Mutation
- (2015) Andrew J. Schwab et al. Stem Cell Reports
- The prevalence of Parkinson's disease: A systematic review and meta-analysis
- (2014) Tamara Pringsheim et al. MOVEMENT DISORDERS
- Physiological Characterisation of Human iPS-Derived Dopaminergic Neurons
- (2014) Elizabeth M. Hartfield et al. PLoS One
- Genetics and genomics of Parkinson’s disease
- (2014) Michelle K Lin et al. Genome Medicine
- Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression
- (2013) Peter Reinhardt et al. Cell Stem Cell
- Advances in the genetics of Parkinson disease
- (2013) Joanne Trinh et al. Nature Reviews Neurology
- The energy cost of action potential propagation in dopamine neurons: clues to susceptibility in Parkinson's disease
- (2013) Eleftheria K. Pissadaki et al. Frontiers in Computational Neuroscience
- Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease
- (2012) Adriana Sánchez-Danés et al. EMBO Molecular Medicine
- Living on the edge with too many mouths to feed: Why dopamine neurons die
- (2012) J. Paul Bolam et al. MOVEMENT DISORDERS
- LRRK2 Phosphorylates Tubulin-Associated Tau but Not the Free Molecule: LRRK2-Mediated Regulation of the Tau-Tubulin Association and Neurite Outgrowth
- (2012) Fumitaka Kawakami et al. PLoS One
- Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson's Disease
- (2012) O. Cooper et al. Science Translational Medicine
- Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case–control study
- (2011) Owen A Ross et al. LANCET NEUROLOGY
- Modelling schizophrenia using human induced pluripotent stem cells
- (2011) Kristen J. Brennand et al. NATURE
- Plus-End-Tracking Proteins and Their Interactions at Microtubule Ends
- (2010) Niels Galjart CURRENT BIOLOGY
- Protein misfolding disorders and macroautophagy
- (2010) Fiona M Menzies et al. CURRENT OPINION IN CELL BIOLOGY
- Parkinson Disease: A Role for Autophagy?
- (2010) Qian Yang et al. NEUROSCIENTIST
- Foxa2 and Nurr1 Synergistically Yield A9 Nigral Dopamine Neurons Exhibiting Improved Differentiation, Function and Cell Survival
- (2010) Hyun-Seob Lee et al. STEM CELLS
- The Parkinson’s disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites
- (2009) Elisa Greggio et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
- (2009) Frank Soldner et al. CELL
- Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon
- (2009) Tomoya Nakatani et al. DEVELOPMENTAL BIOLOGY
- Parkinson's disease: from monogenic forms to genetic susceptibility factors
- (2009) S. Lesage et al. HUMAN MOLECULAR GENETICS
- Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability - a point of convergence in Parkinsonian neurodegeneration?
- (2009) Frank Gillardon JOURNAL OF NEUROCHEMISTRY
- Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis
- (2009) L. Parisiadou et al. JOURNAL OF NEUROSCIENCE
- Single Nigrostriatal Dopaminergic Neurons Form Widely Spread and Highly Dense Axonal Arborizations in the Neostriatum
- (2009) W. Matsuda et al. JOURNAL OF NEUROSCIENCE
- Disease-Specific Induced Pluripotent Stem Cells
- (2008) In-Hyun Park et al. CELL
- The Parkinson Disease-associated Leucine-rich Repeat Kinase 2 (LRRK2) Is a Dimer That Undergoes Intramolecular Autophosphorylation
- (2008) Elisa Greggio et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells
- (2008) Edward D. Plowey et al. JOURNAL OF NEUROCHEMISTRY
- The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules
- (2008) Payal N. Gandhi et al. JOURNAL OF NEUROSCIENCE RESEARCH
- LRRK2 Gly2019Ser penetrance in Arab–Berber patients from Tunisia: a case-control genetic study
- (2008) Mary M Hulihan et al. LANCET NEUROLOGY
- Mitochondria in the aetiology and pathogenesis of Parkinson's disease
- (2008) Anthony HV Schapira LANCET NEUROLOGY
- Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study
- (2008) Daniel G Healy et al. LANCET NEUROLOGY
- Progress in Parkinson's disease—Where do we stand?
- (2008) André Toulouse et al. PROGRESS IN NEUROBIOLOGY
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