The loss of ATP2C1 impairs the DNA damage response and induces altered skin homeostasis: Consequences for epidermal biology in Hailey-Hailey disease

RNA sequencing atopic dermatitis transcriptome profiling provides insights into novel disease mechanisms with potential therapeutic implications

(2015) Mayte Suárez-Fariñas et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Notch down-regulation in regenerated epidermis contributes to enhanced expression of interleukin-36α and suppression of keratinocyte differentiation during wound healing

(2015) Yuko Takazawa et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Using yeast to model calcium-related diseases: Example of the Hailey–Hailey disease

(2014) Cécile Voisset et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mammalian skin cell biology: At the interface between laboratory and clinic

(2014) F. M. Watt   SCIENCE

Inactivation of p53 in Human Keratinocytes Leads to Squamous Differentiation and Shedding via Replication Stress and Mitotic Slippage

(2014) Ana Freije et al.   Cell Reports

Epithelialization in Wound Healing: A Comprehensive Review

(2014) Irena Pastar et al.   Advances in Wound Care

Cell death by cornification

(2013) Leopold Eckhart et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Efficacy of the melanocortin analogue Nle4-D-Phe7-α-melanocyte-stimulating hormone in the treatment of patients with Hailey-Hailey disease

(2013) G. Biolcati et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Cycling up the epidermis: reconciling 100 years of debate

(2013) Alberto Gandarillas et al.   EXPERIMENTAL DERMATOLOGY

IL-33 promotes Staphylococcus aureus-infected wound healing in mice

(2013) Hui Yin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

IL-1 Induces Proinflammatory Leukocyte Infiltration and Regulates Fibroblast Phenotype in the Infarcted Myocardium

(2013) A. Saxena et al.   JOURNAL OF IMMUNOLOGY

IL-33 accelerates cutaneous wound healing involved in upregulation of alternatively activated macrophages

(2013) Hui Yin et al.   MOLECULAR IMMUNOLOGY

The ATM protein kinase: regulating the cellular response to genotoxic stress and more

(2013) Yosef Shiloh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ensembl 2014

(2013) Paul Flicek et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development

(2013) R. B. Hamanaka et al.   Science Signaling

Epigenetic field defects in progression to cancer

(2013) Carol Bernstein   World Journal of Gastrointestinal Oncology

The mysterious human epidermal cell cycle, or an oncogene-induced differentiation checkpoint

(2012) Alberto Gandarillas   CELL CYCLE

Disease gene identification strategies for exome sequencing

(2012) Christian Gilissen et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Targeting of Nrf2 induces DNA damage signaling and protects colonic epithelial cells from ionizing radiation

(2012) S. B. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two Patients With Hailey-Hailey Disease, Multiple Primary Melanomas, and Other Cancers

(2011) Melinda R. Mohr et al.   ARCHIVES OF DERMATOLOGY

Terminally differentiated astrocytes lack DNA damage response signaling and are radioresistant but retain DNA repair proficiency

(2011) L Schneider et al.   CELL DEATH AND DIFFERENTIATION

Oxidative stress activation of miR-125b is part of the molecular switch for Hailey-Hailey disease manifestation

(2011) Sonia Manca et al.   EXPERIMENTAL DERMATOLOGY

Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair

(2011) Lisa Woodbine et al.   NUCLEIC ACIDS RESEARCH

Cutaneous Squamous Cell Carcinoma (SCC) and the DNA Damage Response: pATM Expression Patterns in Pre-Malignant and Malignant Keratinocyte Skin Lesions

(2011) Ferina Ismail et al.   PLoS One

Regulation of cell differentiation by the DNA damage response

(2011) Mara H. Sherman et al.   TRENDS IN CELL BIOLOGY

IL-32 is expressed by human primary keratinocytes and modulates keratinocyte apoptosis in atopic dermatitis

(2010) Norbert Meyer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clustering phenotype populations by genome-wide RNAi and multiparametric imaging

(2010) Florian Fuchs et al.   Molecular Systems Biology

CEP152 is a genome maintenance protein disrupted in Seckel syndrome

(2010) Ersan Kalay et al.   NATURE GENETICS

Unique characteristics of Ca2+ homeostasis of the trans-Golgi compartment

(2010) V. Lissandron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Complex multipathways alterations and oxidative stress are associated with Hailey-Hailey disease

(2009) S. Cialfi et al.   BRITISH JOURNAL OF DERMATOLOGY

Epidermal Notch1 Loss Promotes Skin Tumorigenesis by Impacting the Stromal Microenvironment

(2009) Shadmehr Demehri et al.   CANCER CELL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Human Papillomaviruses Activate the ATM DNA Damage Pathway for Viral Genome Amplification upon Differentiation

(2009) Cary A. Moody et al.   PLoS Pathogens