Triptonide Effectively Inhibits Wnt/β-Catenin Signaling via C-terminal Transactivation Domain of β-catenin

Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the Death Receptor pathway

(2014) Zhiyu Chen et al.   CANCER LETTERS

Modulation of IL-37 expression by triptolide and triptonide in THP-1 cells

(2014) Lingge He et al.   Cellular & Molecular Immunology

A Zebrafish Chemical Suppressor Screening Identifies Small Molecule Inhibitors of the Wnt/β-catenin Pathway

(2014) Naoyuki Nishiya et al.   CHEMISTRY & BIOLOGY

Target Identification for Small Bioactive Molecules: Finding the Needle in the Haystack

(2013) Slava Ziegler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Canonical Wnt signalling as a key regulator of fibrogenesis - implications for targeted therapies?

(2013) Clara Dees et al.   EXPERIMENTAL DERMATOLOGY

Selective Small Molecule Targeting β-Catenin Function Discovered by In Vivo Chemical Genetic Screen

(2013) Jijun Hao et al.   Cell Reports

Synergistic anticancer activity of triptolide combined with cisplatin enhances apoptosis in gastric cancer in vitro and in vivo

(2012) Chia-Jung Li et al.   CANCER LETTERS

Triptolide with Potential Medicinal Value for Diseases of the Central Nervous System

(2012) Yan Zheng et al.   CNS Neuroscience & Therapeutics

Phytochemicals Attenuating Aberrant Activation of β-Catenin in Cancer Cells

(2012) Dan Wang et al.   PLoS One

Kinetic Responses of  -Catenin Specify the Sites of Wnt Control

(2012) A. R. Hernandez et al.   SCIENCE

Membrane sialidase NEU3 is highly expressed in human melanoma cells promoting cell growth with minimal changes in the composition of gangliosides

(2011) Maiko Miyata et al.   CANCER SCIENCE

Triptolide Directly Inhibits dCTP Pyrophosphatase

(2011) Timothy W. Corson et al.   CHEMBIOCHEM

RNA polymerase – An important molecular target of triptolide in cancer cells

(2010) Jingxuan Pan   CANCER LETTERS

Lupeol inhibits proliferation of human prostate cancer cells by targeting  -catenin signaling

(2009) M. Saleem et al.   CARCINOGENESIS

Towards an integrated view of Wnt signaling in development

(2009) R. van Amerongen et al.   DEVELOPMENT

β-Catenin hits chromatin: regulation of Wnt target gene activation

(2009) Christian Mosimann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Suppression of Wnt/β-catenin signaling inhibits prostate cancer cell proliferation

(2008) Wenyan Lu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Crystal Structure of a Full-Length β-Catenin

(2008) Yi Xing et al.   STRUCTURE