Cellular growth defects triggered by an overload of protein localization processes

The Protease Ste24 Clears Clogged Translocons

(2016) Tslil Ast et al.   CELL

Protein lipid modifications-More than just a greasy ballast

(2016) Andreas Hentschel et al.   PROTEOMICS

The Cost of Protein Production

(2016) Moshe Kafri et al.   Cell Reports

Yeast Proteome Dynamics from Single Cell Imaging and Automated Analysis

(2015) Yolanda T. Chong et al.   CELL

MitoFates: Improved Prediction of Mitochondrial Targeting Sequences and Their Cleavage Sites

(2015) Yoshinori Fukasawa et al.   MOLECULAR & CELLULAR PROTEOMICS

Quantitative nature of overexpression experiments

(2015) Hisao Moriya   MOLECULAR BIOLOGY OF THE CELL

Size-dependent leak of soluble and membrane proteins through the yeast nuclear pore complex

(2015) Petra Popken et al.   MOLECULAR BIOLOGY OF THE CELL

A cytosolic network suppressing mitochondria-mediated proteostatic stress and cell death

(2015) Xiaowen Wang et al.   NATURE

Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol

(2015) Lidia Wrobel et al.   NATURE

A palette of fluorescent proteins optimized for diverse cellular environments

(2015) Lindsey M. Costantini et al.   Nature Communications

LocNES: a computational tool for locating classical NESs in CRM1 cargo proteins

(2014) Darui Xu et al.   BIOINFORMATICS

Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

(2014) Nils A Kulak et al.   NATURE METHODS

Rate-Limiting Steps in Yeast Protein Translation

(2013) Premal Shah et al.   CELL

PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone

(2013) Sae-Hun Park et al.   CELL

Evaluating the Fitness Cost of Protein Expression in Saccharomyces cerevisiae

(2013) Katarzyna Tomala et al.   Genome Biology and Evolution

Futile Protein Folding Cycles in the ER Are Terminated by the Unfolded Protein O-Mannosylation Pathway

(2013) C. Xu et al.   SCIENCE

Identification of dosage-sensitive genes in Saccharomyces cerevisiae using the genetic tug-of-war method

(2012) K. Makanae et al.   GENOME RESEARCH

Robustness analysis of cellular systems using the genetic tug-of-war method

(2012) Hisao Moriya et al.   Molecular BioSystems

Targeted protein depletion in Saccharomyces cerevisiae by activation of a bidirectional degron

(2011) Marc Jungbluth et al.   BMC Systems Biology

Overexpression limits of fission yeast cell-cycle regulators in vivo and in silico

(2011) H. Moriya et al.   Molecular Systems Biology

Systematic exploration of essential yeast gene function with temperature-sensitive mutants

(2011) Zhijian Li et al.   NATURE BIOTECHNOLOGY

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

Spatial expression of the genome: the signal hypothesis at forty

(2011) Karl S. Matlin   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of Aneuploidy-Tolerating Mutations

(2010) Eduardo M. Torres et al.   CELL

Cost of Unneeded Proteins in E. coli Is Reduced after Several Generations in Exponential Growth

(2010) Irit Shachrai et al.   MOLECULAR CELL

Mitochondrial protein import: from proteomics to functional mechanisms

(2010) Oliver Schmidt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protein palmitoylation in neuronal development and synaptic plasticity

(2010) Yuko Fukata et al.   NATURE REVIEWS NEUROSCIENCE

NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1

(2010) Thomas Güttler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast

(2010) K. A. Geiler-Samerotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of different promoters for designing a new expression vector in Saccharomyces cerevisiae

(2010) Siavash Partow et al.   YEAST

Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs

(2009) S. Kosugi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cost of Expression of Escherichia coli lac Operon Proteins Is in the Process, Not in the Products

(2008) D. M. Stoebel et al.   GENETICS