Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development

Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation

(2015) Quanlong Lu et al.   NATURE CELL BIOLOGY

EHD3-Dependent Endosome Pathway Regulates Cardiac Membrane Excitability and Physiology

(2014) Jerry Curran et al.   CIRCULATION RESEARCH

EHD1 mediates vesicle trafficking required for normal muscle growth and transverse tubule development

(2014) Avery D. Posey et al.   DEVELOPMENTAL BIOLOGY

Structural Insights into Membrane Interaction and Caveolar Targeting of Dynamin-like EHD2

(2014) Claudio Shah et al.   STRUCTURE

The Ciliary G-Protein-Coupled Receptor Gpr161 Negatively Regulates the Sonic Hedgehog Pathway via cAMP Signaling

(2013) Saikat Mukhopadhyay et al.   CELL

Does your gene need a background check? How genetic background impacts the analysis of mutations, genes, and evolution

(2013) Christopher H. Chandler et al.   TRENDS IN GENETICS

Differential regulation of EHD3 in human and mammalian heart failure

(2012) Hjalti Gudmundsson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The role of primary cilia in the pathophysiology of neural tube defects

(2012) Timothy W. Vogel et al.   Neurosurgical Focus

The Role of EHD Proteins at the Neuronal Synapse

(2012) M. S. Ioannou et al.   Science Signaling

Regulation of Synaptic Vesicle Budding and Dynamin Function by an EHD ATPase

(2011) J. Jakobsson et al.   JOURNAL OF NEUROSCIENCE

Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins

(2011) Christine E. Larkins et al.   MOLECULAR BIOLOGY OF THE CELL

Renal Thrombotic Microangiopathy in Mice with Combined Deletion of Endocytic Recycling Regulators EHD3 and EHD4

(2011) Manju George et al.   PLoS One

Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components

(2011) J. Qin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The relationship between sonic Hedgehog signaling, cilia, and neural tube defects

(2010) Jennifer N. Murdoch et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

The endocytic recycling regulator EHD1 is essential for spermatogenesis and male fertility in mice

(2010) Mark A Rainey et al.   BMC DEVELOPMENTAL BIOLOGY

The Conserved Bardet-Biedl Syndrome Proteins Assemble a Coat that Traffics Membrane Proteins to Cilia

(2010) Hua Jin et al.   CELL

EH Domain Proteins Regulate Cardiac Membrane Protein Targeting

(2010) Hjalti Gudmundsson et al.   CIRCULATION RESEARCH

Ehd4is required to attain normal prepubertal testis size but dispensable for fertility in male mice

(2010) Manju George et al.   GENESIS

Bardet-Biedl Syndrome-associated Small GTPase ARL6 (BBS3) Functions at or near the Ciliary Gate and Modulates Wnt Signaling

(2010) Cheryl J. Wiens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endocytic Recycling Proteins EHD1 and EHD2 Interact with Fer-1-like-5 (Fer1L5) and Mediate Myoblast Fusion

(2010) Avery D. Posey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence

(2010) John A. Follit et al.   JOURNAL OF CELL BIOLOGY

The AP-1 clathrin adaptor facilitates cilium formation and functions with RAB-8 in C. elegans ciliary membrane transport

(2010) O. I. Kaplan et al.   JOURNAL OF CELL SCIENCE

Differential role of Rab proteins in ciliary trafficking: Rab23 regulates Smoothened levels

(2010) C. Boehlke et al.   JOURNAL OF CELL SCIENCE

Kinetics of Hedgehog-Dependent Full-Length Gli3 Accumulation in Primary Cilia and Subsequent Degradation

(2010) X. Wen et al.   MOLECULAR AND CELLULAR BIOLOGY

The endocytic matrix

(2010) Giorgio Scita et al.   NATURE

The primary cilium: a signalling centre during vertebrate development

(2010) Sarah C. Goetz et al.   NATURE REVIEWS GENETICS

Sonic hedgehog in temporal control of somite formation

(2010) T. P. Resende et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coordination of Rab8 and Rab11 in primary ciliogenesis

(2010) A. Knodler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genotype to Phenotype: A Complex Problem

(2010) R. D. Dowell et al.   SCIENCE

EHD proteins: key conductors of endocytic transport

(2010) Naava Naslavsky et al.   TRENDS IN CELL BIOLOGY

Sonic hedgehog maintains proliferation in secondary heart field progenitors and is required for normal arterial pole formation

(2009) Laura A. Dyer et al.   DEVELOPMENTAL BIOLOGY

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved

(2009) M.-H. Chen et al.   GENES & DEVELOPMENT

Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling

(2009) Ryan X. Norman et al.   HUMAN MOLECULAR GENETICS

EHD4 and CDH23 Are Interacting Partners in Cochlear Hair Cells

(2009) Soma Sengupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sonic Hedgehog Regulates Integrin Activity, Cadherin Contacts, and Cell Polarity to Orchestrate Neural Tube Morphogenesis

(2009) C. Fournier-Thibault et al.   JOURNAL OF NEUROSCIENCE

MICAL-L1 Links EHD1 to Tubular Recycling Endosomes and Regulates Receptor Recycling

(2009) Mahak Sharma et al.   MOLECULAR BIOLOGY OF THE CELL

AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling

(2009) Saumya Pant et al.   NATURE CELL BIOLOGY

Pathways and mechanisms of endocytic recycling

(2009) Barth D. Grant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endocytosis and signalling: intertwining molecular networks

(2009) Alexander Sorkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Establishing and Interpreting Graded Sonic Hedgehog Signaling during Vertebrate Neural Tube Patterning: The Role of Negative Feedback

(2009) V. Ribes et al.   Cold Spring Harbor Perspectives in Biology

A simple principle concerning the robustness of protein complex activity to changes in gene expression

(2008) Jennifer I Semple et al.   BMC Systems Biology

Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network

(2008) E. Dessaud et al.   DEVELOPMENT

Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potential

(2008) N. A. Thomas et al.   DEVELOPMENT

FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism

(2008) Ahryon Cho et al.   DEVELOPMENTAL BIOLOGY

A gradient of Shh establishes mutually repressing somitic cell fates induced by Nkx3.2 and Pax3

(2008) Dana M. Cairns et al.   DEVELOPMENTAL BIOLOGY

Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development

(2008) Yong Pan et al.   DEVELOPMENTAL BIOLOGY

Hedgehog: functions and mechanisms

(2008) M. Varjosalo et al.   GENES & DEVELOPMENT

The Endocytic Recycling Protein EHD2 Interacts with Myoferlin to Regulate Myoblast Fusion

(2008) Katherine R. Doherty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tetrahymena IFT122Ais not essential for cilia assembly but plays a role in returning IFT proteins from the ciliary tip to the cell body

(2008) Che-Chia Tsao et al.   JOURNAL OF CELL SCIENCE

elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8

(2008) Yoshihiro Omori et al.   NATURE CELL BIOLOGY

THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia

(2008) Pamela V Tran et al.   NATURE GENETICS

HSP90-buffered genetic variation is common in Arabidopsis thaliana

(2008) T. A. Sangster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Role for EHD4 in the Regulation of Early Endosomal Transport

(2008) Mahak Sharma et al.   TRAFFIC

Mechanisms of EHD/RME-1 Protein Function in Endocytic Transport

(2008) Barth D. Grant et al.   TRAFFIC

Intraflagellar Transport and Functional Analysis of Genes Required for Flagellum Formation in Trypanosomes

(2007) Sabrina Absalon et al.   MOLECULAR BIOLOGY OF THE CELL