HER2 confers drug resistance of human breast cancer cells through activation of NRF2 by direct interaction

Epigenetic modification of Nrf2 in 5-fluorouracil-resistant colon cancer cells: involvement of TET-dependent DNA demethylation

(2014) K A Kang et al.   Cell Death & Disease

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Proteomic Analysis of Ubiquitin Ligase KEAP1 Reveals Associated Proteins That Inhibit NRF2 Ubiquitination

(2013) B. E. Hast et al.   CANCER RESEARCH

HER2-targeted therapy in breast cancer: A systematic review of neoadjuvant trials

(2013) Susan Dent et al.   CANCER TREATMENT REVIEWS

Regulation of Nrf2—an update

(2013) Suryakant K. Niture et al.   FREE RADICAL BIOLOGY AND MEDICINE

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival

(2013) Chiara Gorrini et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation

(2012) Holly K. Bryan et al.   BIOCHEMICAL PHARMACOLOGY

The importance of HER2 signaling in the tumor-initiating cell population in aromatase inhibitor-resistant breast cancer

(2012) Rabia A. Gilani et al.   BREAST CANCER RESEARCH AND TREATMENT

NRF2 inhibition represses ErbB2 signaling in ovarian carcinoma cells: Implications for tumor growth retardation and docetaxel sensitivity

(2012) Sarala Manandhar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Wilms Tumor Gene on X Chromosome (WTX) Inhibits Degradation of NRF2 Protein through Competitive Binding to KEAP1 Protein

(2012) Nathan D. Camp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/ -TrCP Axis

(2012) P. Rada et al.   MOLECULAR AND CELLULAR BIOLOGY

PALB2 Interacts with KEAP1 To Promote NRF2 Nuclear Accumulation and Function

(2012) J. Ma et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers

(2012) T Yamadori et al.   ONCOGENE

Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity

(2012) S Chowdhry et al.   ONCOGENE

Up-regulation of breast cancer resistance protein plays a role in HER2-mediated chemoresistance through PI3K/Akt and nuclear factor-kappa B signaling pathways in MCF7 breast cancer cells

(2011) W. Zhang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Nuclear ErbB2 Enhances Translation and Cell Growth by Activating Transcription of Ribosomal RNA Genes

(2011) L.-Y. Li et al.   CANCER RESEARCH

SCF/ -TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner

(2011) P. Rada et al.   MOLECULAR AND CELLULAR BIOLOGY

Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy

(2011) Adam Lister et al.   Molecular Cancer

Mechanisms of Endocrine Resistance in Breast Cancer

(2010) C. Kent Osborne et al.   Annual Review of Medicine

CR6-interacting Factor 1 (CRIF1) Regulates NF-E2-related Factor 2 (NRF2) Protein Stability by Proteasome-mediated Degradation

(2010) Hyo Jin Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progesterone Receptor Induces ErbB-2 Nuclear Translocation To Promote Breast Cancer Growth via a Novel Transcriptional Effect: ErbB-2 Function as a Coactivator of Stat3

(2010) W. Beguelin et al.   MOLECULAR AND CELLULAR BIOLOGY

Nuclear Factor (Erythroid-Derived 2)-Like 2 Regulates Drug Resistance in Pancreatic Cancer Cells

(2010) Young Bin Hong et al.   PANCREAS

Nrf2 Enhances Cell Proliferation and Resistance to Anticancer Drugs in Human Lung Cancer

(2009) S. Homma et al.   CLINICAL CANCER RESEARCH

Direct Interaction between Nrf2 and p21Cip1/WAF1 Upregulates the Nrf2-Mediated Antioxidant Response

(2009) Weimin Chen et al.   MOLECULAR CELL

RNAi-Mediated Silencing of Nuclear Factor Erythroid-2-Related Factor 2 Gene Expression in Non-Small Cell Lung Cancer Inhibits Tumor Growth and Increases Efficacy of Chemotherapy

(2008) A. Singh et al.   CANCER RESEARCH