mtDNA germ line variation mediated ROS generates retrograde signaling and induces pro-cancerous metabolic features

Mutational patterns in the breast cancer mitochondrial genome, with clinical correlates

(2014) Sarah McMahon et al.   CARCINOGENESIS

Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation

(2014) M Ogrunc et al.   CELL DEATH AND DIFFERENTIATION

Pathogenesis of Human Mitochondrial Diseases Is Modulated by Reduced Activity of the Ubiquitin/Proteasome System

(2014) Alexandra Segref et al.   Cell Metabolism

Missense Mutations in Pyruvate Kinase M2 Promote Cancer Metabolism, Oxidative Endurance, Anchorage Independence, and Tumor Growth in a Dominant Negative Manner

(2014) Mohd Askandar Iqbal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A mitochondrial bioenergetic etiology of disease

(2013) Douglas C. Wallace   JOURNAL OF CLINICAL INVESTIGATION

Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2

(2013) Mohd Iqbal et al.   Molecular Cancer

Mutations that affect mitochondrial functions and their association with neurodegenerative diseases

(2013) Varinderpal S. Dhillon et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

The pathogenicity scoring system for mitochondrial tRNA mutations revisited

(2013) Emiliano González-Vioque et al.   Molecular Genetics & Genomic Medicine

Mitochondria: In Sickness and in Health

(2012) Jodi Nunnari et al.   CELL

Mitochondrial Control of Cellular Life, Stress, and Death

(2012) Lorenzo Galluzzi et al.   CIRCULATION RESEARCH

Reactive oxygen species regulate ERBB2 and ERBB3 expression via miR-199a/125b and DNA methylation

(2012) Jun He et al.   EMBO REPORTS

Regulation of intracellular signalling through cysteine oxidation by reactive oxygen species

(2012) H. Miki et al.   JOURNAL OF BIOCHEMISTRY

Spectrum of somatic mitochondrial mutations in five cancers

(2012) T. C. Larman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Inherited Heteroplasmic Mutation in Mitochondrial Gene COI in a Patient with Prostate Cancer Alters Reactive Oxygen, Reactive Nitrogen and Proliferation

(2012) Rebecca S. Arnold et al.   Biomed Research International

Mitochondrial DNA Sequence Variation and Risk of Pancreatic Cancer

(2011) E. T. Lam et al.   CANCER RESEARCH

Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer

(2011) J. H. Kim et al.   GENOME RESEARCH

Signal transduction by reactive oxygen species

(2011) Toren Finkel   JOURNAL OF CELL BIOLOGY

Investigation of DNA damage response and apoptotic gene methylation pattern in sporadic breast tumors using high throughput quantitative DNA methylation analysis technology

(2011) Ranjana Pal et al.   Molecular Cancer

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

(2011) D. Anastasiou et al.   SCIENCE

ROS signaling: the new wave?

(2011) Ron Mittler et al.   TRENDS IN PLANT SCIENCE

A common mitochondrial polymorphism 10398A>G is associated metabolic syndrome in a Chinese population

(2010) Suh-Hang H. Juo et al.   MITOCHONDRION

Association of mitochondrial haplogroup D and risk of esophageal cancer in Taihang Mountain and Chaoshan areas in China

(2010) Xiao-Yun Li et al.   MITOCHONDRION

Mitochondrial NADH-dehydrogenase subunit 3 (ND3) polymorphism (A10398G) and sporadic breast cancer in Poland

(2009) Anna M. Czarnecka et al.   BREAST CANCER RESEARCH AND TREATMENT

Differential Behavior of Missense Mutations in the Intersubunit Contact Domain of the Human Pyruvate Kinase M2Isozyme

(2009) Kamal Akhtar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mitochondrial A10398G Polymorphism, Interaction with Alcohol Consumption, and Breast Cancer Risk

(2009) Annamaria Pezzotti et al.   PLoS One

Pathogenic Mitochondrial DNA Mutations Are Common in the General Population

(2008) Hannah R. Elliott et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mitochondrial Cytochrome B Gene Mutation Promotes Tumor Growth in Bladder Cancer

(2008) S. Dasgupta et al.   CANCER RESEARCH

Concomitant presence of mutations in mitochondrial genome andp53in cancer development-A study in north Indian sporadic breast and esophageal cancer patients

(2008) Sailesh Gochhait et al.   INTERNATIONAL JOURNAL OF CANCER

Identification of the Mitochondrial ND3 Subunit as a Structural Component Involved in the Active/Deactive Enzyme Transition of Respiratory Complex I

(2008) Alexander Galkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial DNA variant interactions modify breast cancer risk

(2008) Daniel Covarrubias et al.   JOURNAL OF HUMAN GENETICS

Mitochondrial Transmembrane Potential and Reactive Oxygen Species Generation Regulate the Enhanced Effect of CCCP on TRAIL-Induced SNU-638 Cell Apoptosis

(2008) Atul A. CHAUDHARI et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Coordination of gene expression between organellar and nuclear genomes

(2008) Jesse D. Woodson et al.   NATURE REVIEWS GENETICS