Mutational patterns in the breast cancer mitochondrial genome, with clinical correlates

MitoSeek: extracting mitochondria information and performing high-throughput mitochondria sequencing analysis

(2013) Yan Guo et al.   BIOINFORMATICS

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Universal heteroplasmy of human mitochondrial DNA

(2012) B. A. I. Payne et al.   HUMAN MOLECULAR GENETICS

Is mitochondrial DNA content a potential biomarker of mitochondrial dysfunction?

(2012) Afshan N. Malik et al.   MITOCHONDRION

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Mitochondrial genomes gleaned from human whole-exome sequencing

(2012) Ernesto Picardi et al.   NATURE METHODS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Identification of high-confidence somatic mutations in whole genome sequence of formalin-fixed breast cancer specimens

(2012) Shawn E. Yost et al.   NUCLEIC ACIDS RESEARCH

Spectrum of somatic mitochondrial mutations in five cancers

(2012) T. C. Larman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CNVnator: An approach to discover, genotype, and characterize typical and atypical CNVs from family and population genome sequencing

(2011) A. Abyzov et al.   GENOME RESEARCH

Prognostic implications and molecular associations of NADH dehydrogenase subunit 4 (ND4) mutations in acute myeloid leukemia

(2011) F Damm et al.   LEUKEMIA

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

How mutations in tRNA distant from the anticodon affect the fidelity of decoding

(2011) T Martin Schmeing et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Somatic Mutations throughout the Entire Mitochondrial Genome Are Associated with Elevated PSA Levels in Prostate Cancer Patients

(2010) Anita Kloss-Brandstätter et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Accumulation of mutations over the entire mitochondrial genome of breast cancer cells obtained by tissue microdissection

(2010) Liane Fendt et al.   BREAST CANCER RESEARCH AND TREATMENT

Breast Cancer in the Personal Genomics Era

(2010) Rachel E. Ellsworth et al.   CURRENT GENOMICS

Evaluating mitochondrial DNA in patients with breast cancer and benign breast disease

(2010) Lijun Shen et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis

(2009) Jianxin Lu et al.   CELL RESEARCH

mtDNA mutation pattern in tumors and human evolution are shaped by similar selective constraints

(2009) I. Zhidkov et al.   GENOME RESEARCH

Mitochondrial DNA content in paired normal and cancerous breast tissue samples from patients with breast cancer

(2009) Alex Xiu-Cheng Fan et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Loss of Complex I due to Mitochondrial DNA Mutations in Renal Oncocytoma

(2008) J. A. Mayr et al.   CLINICAL CANCER RESEARCH

High-resolution mapping of copy-number alterations with massively parallel sequencing

(2008) Derek Y Chiang et al.   NATURE METHODS

Mitochondria as targets for cancer chemotherapy

(2008) Vladimir Gogvadze et al.   SEMINARS IN CANCER BIOLOGY