Llama immunization with full-length VAR2CSA generates cross-reactive and inhibitory single-domain antibodies against the DBL1X domain

A general protocol for the generation of Nanobodies for structural biology

(2014) Els Pardon et al.   Nature Protocols

Utilizing Nanobody Technology to Target Non-Immunodominant Domains of VAR2CSA

(2014) Sisse B. Ditlev et al.   PLoS One

VHH (nanobody) directed against human glycophorin A: A tool for autologous red cell agglutination assays

(2013) Ibrahim Habib et al.   ANALYTICAL BIOCHEMISTRY

Nanobodies: Natural Single-Domain Antibodies

(2013) Serge Muyldermans   Annual Review of Biochemistry

Malaria's deadly grip: cytoadhesion ofPlasmodium falciparum-infected erythrocytes

(2013) Joseph D. Smith et al.   CELLULAR MICROBIOLOGY

Differential adhesion-inhibitory patterns of antibodies raised against two major variants of the NTS-DBL2X region of VAR2CSA

(2013) Justin Doritchamou et al.   VACCINE

Structural and Functional Insight into How thePlasmodium falciparumVAR2CSA Protein Mediates Binding to Chondroitin Sulfate A in Placental Malaria

(2012) Thomas M. Clausen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

First-Trimester Plasmodium falciparum Infections Display a Typical “Placental” Phenotype

(2012) Justin Doritchamou et al.   JOURNAL OF INFECTIOUS DISEASES

High Avidity Antibodies to Full-Length VAR2CSA Correlate with Absence of Placental Malaria

(2012) Yeung Lo Tutterrow et al.   PLoS One

Identification of Id1-DBL2X of VAR2CSA as a key domain inducing highly inhibitory and cross-reactive antibodies

(2012) Bita Bordbar et al.   VACCINE

Nanobody; an Old Concept and New Vehicle for Immunotargeting

(2011) Fatemeh Rahbarizadeh et al.   IMMUNOLOGICAL INVESTIGATIONS

The Chondroitin Sulfate A-binding Site of the VAR2CSA Protein Involves Multiple N-terminal Domains

(2011) Madeleine Dahlbäck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The NTS-DBL2X Region of VAR2CSA Induces Cross-Reactive Antibodies That Inhibit Adhesion of Several Plasmodium falciparum Isolates to Chondroitin Sulfate A

(2011) Pascal Bigey et al.   JOURNAL OF INFECTIOUS DISEASES

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

Crystal structure of a heterodimer of editosome interaction proteins in complex with two copies of a cross-reacting nanobody

(2011) Young-Jun Park et al.   NUCLEIC ACIDS RESEARCH

Var2CSA Minimal CSA Binding Region Is Located within the N-Terminal Region

(2011) Anand Srivastava et al.   PLoS One

Malaria in pregnancy: small babies, big problem

(2011) Alexandra J. Umbers et al.   TRENDS IN PARASITOLOGY

The pathogenesis of Plasmodium falciparum malaria in humans: insights from splenic physiology

(2010) P. A. Buffet et al.   BLOOD

Full-Length Recombinant Plasmodium falciparum VAR2CSA Binds Specifically to CSPG and Induces Potent Parasite Adhesion-Blocking Antibodies

(2010) Pongsak Khunrae et al.   JOURNAL OF MOLECULAR BIOLOGY

Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA

(2010) A. Srivastava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High efficacy of anti DBL4ɛ-VAR2CSA antibodies in inhibition of CSA-binding Plasmodium falciparum-infected erythrocytes from pregnant women

(2010) Pamela A. Magistrado et al.   VACCINE

Specific immuno capturing of the Staphylococcal superantigen toxic-shock syndrome toxin-1 in plasma

(2009) Hendrik Adams et al.   BIOTECHNOLOGY AND BIOENGINEERING

Toward chaperone-assisted crystallography: Protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold

(2008) Valentina Tereshko et al.   PROTEIN SCIENCE