Implementation of a dynamic intestinal gut-on-a-chip barrier model for transport studies of lipophilic dioxin congeners

Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and biphenyls (PCBs) in home-produced eggs

(2016) Ron L.A.P. Hoogenboom et al.   CHEMOSPHERE

Geometry optimization method versus predictive ability in QSPR modeling for ionic liquids

(2016) Anna Rybinska et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Organization of Endothelial Cells, Pericytes, and Astrocytes into a 3D Microfluidic in Vitro Model of the Blood–Brain Barrier

(2016) Jack D. Wang et al.   MOLECULAR PHARMACEUTICS

From dioxin to dioxin congeners: understanding the differences in hydrophobic aggregation in water and absorption into lipid membranes by means of atomistic simulations

(2016) Mosé Casalegno et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Polymer Microfluidics: Simple, Low-Cost Fabrication Process Bridging Academic Lab Research to Commercialized Production

(2016) Chia-Wen Tsao   Micromachines

Human Intestinal Barrier Function in Health and Disease

(2016) Julia König et al.   Clinical and Translational Gastroenterology

Investigating Nonalcoholic Fatty Liver Disease in a Liver-on-a-Chip Microfluidic Device

(2016) Manuele Gori et al.   PLoS One

Organs-on-chips at the frontiers of drug discovery

(2015) Eric W. Esch et al.   NATURE REVIEWS DRUG DISCOVERY

PubChem Substance and Compound databases

(2015) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

Fluid shear triggers microvilli formation via mechanosensitive activation of TRPV6

(2015) Shigenori Miura et al.   Nature Communications

Organ-on-a-chip platforms for studying drug delivery systems

(2014) Nupura S. Bhise et al.   JOURNAL OF CONTROLLED RELEASE

Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation

(2013) Hyun Jung Kim et al.   Integrative Biology

QSARINS: A new software for the development, analysis, and validation of QSAR MLR models

(2013) Paola Gramatica et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

QSAR Modeling: Where Have You Been? Where Are You Going To?

(2013) Artem Cherkasov et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evaluation of the Absorption of Methotrexate on Cells and Its Cytotoxicity Assay by Using an Integrated Microfluidic Device Coupled to a Mass Spectrometer

(2012) Dan Gao et al.   ANALYTICAL CHEMISTRY

Quantitative Analysis of Molecular Absorption into PDMS Microfluidic Channels

(2012) Jack D. Wang et al.   ANNALS OF BIOMEDICAL ENGINEERING

Engineers are from PDMS-land, Biologists are from Polystyrenia

(2012) Erwin Berthier et al.   LAB ON A CHIP

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

(2012) Hyun Jung Kim et al.   LAB ON A CHIP

Characterization of drug permeability in Caco-2 monolayers by mass spectrometry on a membrane-based microfluidic device

(2012) Dan Gao et al.   LAB ON A CHIP

Theoretical Molecular Descriptors Relevant to the Uptake of Persistent Organic Pollutants from Soil by Zucchini. A QSAR Study

(2011) Barna Bordás et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Real External Predictivity of QSAR Models: How To Evaluate It? Comparison of Different Validation Criteria and Proposal of Using the Concordance Correlation Coefficient

(2011) Nicola Chirico et al.   Journal of Chemical Information and Modeling

Imitation of drug metabolism in human liver and cytotoxicity assay using a microfluidic device coupled to mass spectrometric detection

(2011) Sifeng Mao et al.   LAB ON A CHIP

Adsorption of proteins to thin-films of PDMS and its effect on the adhesion of human endothelial cells

(2011) Karin Y. Chumbimuni-Torres et al.   RSC Advances

A self-adaptive genetic algorithm-artificial neural network algorithm with leave-one-out cross validation for descriptor selection in QSAR study

(2010) Jingheng Wu et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Best Practices for QSAR Model Development, Validation, and Exploitation

(2010) Alexander Tropsha   Molecular Informatics

Drug Permeability Assay Using Microhole-Trapped Cells in a Microfluidic Device

(2009) Ju Hun Yeon et al.   ANALYTICAL CHEMISTRY

Characterization of a gastrointestinal tract microscale cell culture analog used to predict drug toxicity

(2009) Gretchen J. Mahler et al.   BIOTECHNOLOGY AND BIOENGINEERING

Intestinal barrier function: Molecular regulation and disease pathogenesis

(2009) Katherine R. Groschwitz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells

(2009) Kyung-Jin Jang et al.   LAB ON A CHIP

Toxicology for the twenty-first century

(2009) Thomas Hartung   NATURE

Apparent Half-Lives of Dioxins, Furans, and Polychlorinated Biphenyls as a Function of Age, Body Fat, Smoking Status, and Breast-Feeding

(2008) Meghan O’Grady Milbrath et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Calculation of Quantum-Mechanical Descriptors for QSPR at the DFT Level: Is It Necessary?

(2008) Tomasz Puzyn et al.   Journal of Chemical Information and Modeling

ConGENER – A Tool for Modeling of the Congeneric Sets of Environmental Pollutants

(2008) Maciej Haranczyk et al.   Quantitative structure-activity relationships & combinatorial science

Gene expression profiling in Caco-2 human colon cells exposed to TCDD, benzo[a]pyrene, and natural Ah receptor agonists from cruciferous vegetables and citrus fruits

(2007) W.J. de Waard et al.   TOXICOLOGY IN VITRO