“On water” highly atom economical and rapid synthesis of a novel class of 3-hydroxy-2-oxindole scaffolds under a catalyst-free and column chromatography-free protocol at room temperature

Highly regioselective and metal-free γ-addition of β-keto esters to isatins, catalyzed by DABCO: direct access to novel class of diversely functionalized 3-hydroxy-2-oxindole scaffolds

(2013) Pramod Bhagwan Thakur et al.   TETRAHEDRON

Discovery of pyrazole carboxylic acids as potent inhibitors of rat long chain l-2-hydroxy acid oxidase

(2012) Dinesh A. Barawkar et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of C6-azolyl purine nucleosides via C–N coupling reaction of unprotected 6-chloropurine nucleosides and N-heterocycles under catalyst- and solvent-free conditions

(2012) Gui-Rong Qu et al.   GREEN CHEMISTRY

Catalyst free approach to benzimidazoles using air as the oxidant at room temperature

(2012) Chun Zhang et al.   GREEN CHEMISTRY

An eco-friendly sequential catalyst- and solvent-free four-component stereoselective synthesis of novel 1,4-pyranonaphthoquinones

(2012) Balasubramanian Devi Bala et al.   GREEN CHEMISTRY

Catalyst-free hydroarylation of in situ generated ortho-quinone methide (o-QM) with electron rich arenes in water

(2012) Atul Kumar et al.   GREEN CHEMISTRY

Design and synthesis of benzylpyrazolyl coumarin derivatives via a four-component reaction in water: investigation of the weak interactions accumulating in the crystal structure of a signified compound

(2012) Partha Pratim Ghosh et al.   GREEN CHEMISTRY

Isopropenyl acetate, a remarkable, cheap and acylating agent of amines under solvent- and catalyst-free conditions: a systematic investigation

(2012) Romina Pelagalli et al.   GREEN CHEMISTRY

Solvent- and catalyst-free regioselective hydrophosphanation of alkenes

(2012) Francisco Alonso et al.   GREEN CHEMISTRY

A catalyst-free reaction in water: synthesis of benzo[4,5]imidazo[1,2-a]pyrimido[4,5-d]pyrimidin-4(1H)-one derivatives

(2012) Junhua Liu et al.   GREEN CHEMISTRY

Efficient and catalyst-free condensation of acid chlorides and alcohols using continuous flow

(2012) Frederik E. A. Van Waes et al.   GREEN CHEMISTRY

Highly atom-economic, catalyst- and solvent-free oxidation of sulfides into sulfones using 30% aqueous H2O2

(2012) Marjan Jereb   GREEN CHEMISTRY

Non-Catalytic Thermal Multicomponent Assembling of Isatin, Cyclic CH-Acids and Malononitrile: An Efficient Approach to Spirooxindole Scaffold

(2012) Michail N. Elinson et al.   MENDELEEV COMMUNICATIONS

Microwave assisted catalyst-free synthesis of azaarene-substituted 3-hydroxy-2-oxindoles by the functionalization of sp3 C–H bond in methyl pyridine

(2012) H.M. Meshram et al.   TETRAHEDRON LETTERS

DABCO-mediated one-pot sequential transformation: convenient access to fluorinated 1H-pyrazol-5(4H)-ones

(2012) Jun-Wei Wu et al.   TETRAHEDRON LETTERS

Synthesis of important β-functionalized 5-methyl-1H-pyrazol-3-ol derivatives in the presence of γ-alumina catalyst in aqueous medium

(2012) Md. Rumum Rohman et al.   TETRAHEDRON LETTERS

Highly Enantioselective Michael Addition of Pyrazolin-5-ones Catalyzed by Chiral Metal/N,N′-Dioxide Complexes: Metal-Directed Switch in Enantioselectivity

(2011) Zhen Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A facile four-component sequential protocol in the expedient synthesis of novel 2-aryl-5-methyl-2,3-dihydro-1H-3-pyrazolones in water and their antitubercular evaluation

(2011) Pethaiah Gunasekaran et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Highly Stereoselective Synthesis of Spiropyrazolones

(2011) Andrea-Nekane R. Alba et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A grinding-induced catalyst- and solvent-free synthesis of highly functionalized 1,4-dihydropyridines via a domino multicomponent reaction

(2011) Atul Kumar et al.   GREEN CHEMISTRY

Functional ionic liquid mediated synthesis (FILMS) of dihydrothiophenes and tacrine derivatives

(2011) Atul Kumar et al.   GREEN CHEMISTRY

l-Proline catalysed multicomponent synthesis of 3-amino alkylated indolesvia a Mannich-type reaction under solvent-free conditions

(2011) Atul Kumar et al.   GREEN CHEMISTRY

Asymmetric α-Amination of 4-Substituted Pyrazolones Catalyzed by a Chiral Gd(OTf)3/N,N′-Dioxide Complex: Highly Enantioselective Synthesis of 4-Amino-5-pyrazolone Derivatives

(2011) Zhigang Yang et al.   ORGANIC LETTERS

Solvent-Free One-Pot Synthesis of Spiro[indoline-3,4′(1H′)-pyrano[2,3-c]pyrazol]-2-one Derivatives by Grinding

(2011) Ying Liu et al.   SYNTHETIC COMMUNICATIONS

Diastereoselective Mukaiyama aldol reaction of (N-alkyl) isatins with 2-(trimethylsilyloxy)furan by using lanthanum triflate

(2011) Harshadas Mitaram Meshram et al.   TETRAHEDRON

Catalyst-free, aqueous and highly diastereoselective synthesis of new 5-substituted 1H-tetrazoles via a multi-component domino Knoevenagel condensation/1,3 dipolar cycloaddition reaction

(2011) Zeinab Noroozi Tisseh et al.   TETRAHEDRON

An efficient and environmentally friendly DABCO catalyzed Henry reaction of isatins

(2011) H.M. Meshram et al.   TETRAHEDRON LETTERS

Potent and Selective Inhibitors of Long Chain l-2-Hydroxy Acid Oxidase Reduced Blood Pressure in DOCA Salt-Treated Rats

(2011) Dinesh A. Barawkar et al.   ACS Medicinal Chemistry Letters

Organocatalytic Asymmetric Michael Addition of Pyrazolin-5-ones to Nitroolefins with Bifunctional Thiourea: Stereocontrolled Construction of Contiguous Quaternary and Tertiary Stereocenters

(2010) Yu-Hua Liao et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

(2010) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Water: Nature’s Reaction Enforcer—Comparative Effects for Organic Synthesis “In-Water” and “On-Water”

(2010) Richard N. Butler et al.   CHEMICAL REVIEWS

Microwave-Assisted, Aqueous Wittig Reactions: Organic-Solvent- and Protecting-Group-Free Chemoselective Synthesis of Functionalized Alkenes

(2010) James McNulty et al.   CHEMISTRY-A EUROPEAN JOURNAL

Green chemistry by nano-catalysis

(2010) Vivek Polshettiwar et al.   GREEN CHEMISTRY

An expeditious, highly efficient, catalyst-free and solvent-free synthesis of nitroamines and nitrosulfides by Michael addition

(2010) Garima Choudhary et al.   GREEN CHEMISTRY

Microwave-Assisted One-Pot Synthesis of Pyrazolone Derivatives under Solvent-Free Conditions

(2010) Ruoqun Ma et al.   MOLECULES

A short synthesis of the anti-leukemic sesquiterpene (+)-caparratriene employing aqueous Wittig chemistry

(2010) Priyabrata Das et al.   TETRAHEDRON LETTERS

A direct synthesis of functionalized styrenes and terminal 1,3-dienes via aqueous Wittig chemistry with formalin

(2010) Priyabrata Das et al.   TETRAHEDRON LETTERS

Oxindole Synthesis by Direct Coupling of C sp 2H and C sp 3H Centers

(2009) Yi-Xia Jia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis, biological evaluation, and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis: Part 2. Synthesis of rigid pyrazolones

(2009) Daniele Castagnolo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Organic Synthesis “On Water”

(2009) Arani Chanda et al.   CHEMICAL REVIEWS

Asymmetric 1,3-dipolar cycloadditions of acrylamides

(2009) Marie Kissane et al.   CHEMICAL SOCIETY REVIEWS

Highly Stereoselective and General Synthesis of (E)-Stilbenes and Alkenes by Means of an Aqueous Wittig Reaction

(2009) James McNulty et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Pharmacophore and docking-based combined in-silico study of KDR inhibitors

(2009) F.A. Pasha et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Enantioselective Synthesis of β-(3-Hydroxypyrazol-1-yl) Ketones Using an Organocatalyzed Michael Addition Reaction

(2009) Sanjib Gogoi et al.   ORGANIC LETTERS

Triton B–Assisted, Efficient, and Convenient Synthesis of 3-Indolyl-3-hydroxy Oxindoles in Aqueous Medium

(2009) H. M. Meshram et al.   SYNTHETIC COMMUNICATIONS

Aqueous Wittig reactions of semi-stabilized ylides. A straightforward synthesis of 1,3-dienes and 1,3,5-trienes

(2009) James McNulty et al.   TETRAHEDRON LETTERS

Organocatalyzed enantioselective synthesis of 6-amino-5-cyanodihydropyrano[2,3-c]pyrazoles

(2009) Sanjib Gogoi et al.   TETRAHEDRON LETTERS

Microwave-assisted organocatalytic multicomponent Knoevenagel/hetero Diels–Alder reaction for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles

(2009) Marco Radi et al.   TETRAHEDRON LETTERS

Discovery of new Gram-negative antivirulence drugs: Structure and properties of novel E. coli WaaC inhibitors

(2008) F. Moreau et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Chiral N-heterocyclic carbene ligands for asymmetric catalytic oxindole synthesis

(2008) Yi-Xia Jia et al.   CHEMICAL COMMUNICATIONS

An efficient, catalyst- and solvent-free, four-component, and one-pot synthesis of polyhydroquinolines on grinding

(2007) Satish Kumar et al.   TETRAHEDRON