Synthesis of 1-substituted epibatidine analogues and their in vitro and in vivo evaluation as α4β2nicotinic acetylcholine receptor ligands

Impulsive Behavior and Nicotinic Acetylcholine Receptors

(2012) Yu Ohmura et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Nicotinic acetylcholine receptors: From basic science to therapeutics

(2012) Raymond Hurst et al.   PHARMACOLOGY & THERAPEUTICS

Nicotinic Acetylcholine Receptor Agonists Attenuate Septic Acute Kidney Injury in Mice by Suppressing Inflammation and Proteasome Activity

(2012) Prodyot K. Chatterjee et al.   PLoS One

Potentiation of analgesic efficacy but not side effects: Co-administration of an α4β2 neuronal nicotinic acetylcholine receptor agonist and its positive allosteric modulator in experimental models of pain in rats

(2011) Chang Z. Zhu et al.   BIOCHEMICAL PHARMACOLOGY

Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: Advantages and limitations

(2011) Dustin K. Williams et al.   BIOCHEMICAL PHARMACOLOGY

Nicotinic acetylcholine receptor ligands, a patent review (2006 – 2011)

(2011) Daniela Gündisch et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Molecular obesity, potency and other addictions in drug discovery

(2011) Michael M. Hann   MedChemComm

Nicotinic Acetylcholine Receptor Interaction with β -Amyloid: Molecular, Cellular, and Physiological Consequences

(2010) H. Parri et al.   Current Alzheimer Research

Targeting α7 Nicotinic Acetylcholine Receptors in the Treatment of Schizophrenia

(2010) Mihaly Hajos et al.   CURRENT PHARMACEUTICAL DESIGN

A Straightforward Entry to 7-Azabicyclo[2.2.1]heptane-1-carbonitriles in the Synthesis of Novel Epibatidine Analogues

(2010) Thomas Heugebaert et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

 6 2* and  4 2* Nicotinic Receptors Both Regulate Dopamine Signaling with Increased Nigrostriatal Damage: Relevance to Parkinson's Disease

(2010) X. A. Perez et al.   MOLECULAR PHARMACOLOGY

Nicotinic acetylcholine receptors and depression: a review of the preclinical and clinical literature

(2010) Noah S. Philip et al.   PSYCHOPHARMACOLOGY

A safe production method for acetone cyanohydrin

(2010) Thomas S.A. Heugebaert et al.   TETRAHEDRON LETTERS

Characterisation of nicotine receptors on human peripheral blood mononuclear cells (PBMC)

(2009) A. Wongsriraksa et al.   INFLAMMATION RESEARCH

Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system

(2009) Antoine Taly et al.   NATURE REVIEWS DRUG DISCOVERY

Nicotinic acetylcholine receptor agonism: Progress in the management of neuropathic pain?

(2009) Søren H. Sindrup   PAIN

A cog in cognition: How the α7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits

(2009) Steven C. Leiser et al.   PHARMACOLOGY & THERAPEUTICS

Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function

(2009) Edson X. Albuquerque et al.   PHYSIOLOGICAL REVIEWS

Nicotinic Acetylcholine Receptors are Possible Therapeutic Targets for Schizophrenia

(2009) Shuntaro KOHNOMI et al.   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

Activation of nicotinic acetylcholine receptor prevents the production of reactive oxygen species in fibrillar β amyloid peptide (1-42)-stimulated microglia

(2008) Ju Hyun Moon et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Receptor-mediated tobacco toxicity: acceleration of sequential expression of α5 and α7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke

(2008) Juan Arredondo et al.   FASEB JOURNAL

Potential Nicotinic Acetylcholine Receptor Ligands from 2,4-Methanoproline Derivatives

(2008) Anup B. Patel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nicotine and Parkinson's disease: Implications for therapy

(2008) Maryka Quik et al.   MOVEMENT DISORDERS

The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation

(2007) W J Jonge et al.   BRITISH JOURNAL OF PHARMACOLOGY