Nicotinic acetylcholine receptor ligands, a patent review (2006 – 2011)

Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: Advantages and limitations

(2011) Dustin K. Williams et al.   BIOCHEMICAL PHARMACOLOGY

Naturally-expressed nicotinic acetylcholine receptor subtypes

(2011) Jie Wu et al.   BIOCHEMICAL PHARMACOLOGY

Nicotinic acetylcholine receptor-mediated mechanisms in lung cancer

(2011) Ma. Reina Improgo et al.   BIOCHEMICAL PHARMACOLOGY

Structural Basis of Agonist Selectivity for Different nAChR Subtypes: Insights from Crystal Structures, Mutation Experiments and Molecular Simulations

(2011) Ruo-Xu Gu et al.   CURRENT PHARMACEUTICAL DESIGN

Pharmacotherapy for Smoking Cessation: Present and Future

(2011) Henri-Jean Aubin et al.   CURRENT PHARMACEUTICAL DESIGN

Assembly of nicotinic and other Cys-loop receptors

(2011) Victor Tsetlin et al.   JOURNAL OF NEUROCHEMISTRY

86 Rb + efflux mediated by α4β2*-nicotinic acetylcholine receptors with high and low-sensitivity to stimulation by acetylcholine display similar agonist-induced desensitization

(2010) Michael J. Marks et al.   BIOCHEMICAL PHARMACOLOGY

Psychiatric Adverse Events in Randomized, Double-Blind, Placebo-Controlled Clinical Trials of Varenicline

(2010) Serena Tonstad et al.   DRUG SAFETY

Enhancement of Attentional Performance by Selective Stimulation of α4β2* nAChRs: Underlying Cholinergic Mechanisms

(2010) William M Howe et al.   NEUROPSYCHOPHARMACOLOGY

From smoking to lung cancer: the CHRNA5/A3/B4 connection

(2010) M R D Improgo et al.   ONCOGENE

Nicotinic pharmacophore: The pyridine N of nicotine and carbonyl of acetylcholine hydrogen bond across a subunit interface to a backbone NH

(2010) A. P. Blum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nicotine receptors and depression: revisiting and revising the cholinergic hypothesis

(2010) Yann S. Mineur et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Stimulation of dopamine release by nicotinic acetylcholine receptor ligands in rat brain slices correlates with the profile of high, but not low, sensitivity α4β2 subunit combination

(2009) David J. Anderson et al.   BIOCHEMICAL PHARMACOLOGY

Structural and functional diversity of native brain neuronal nicotinic receptors

(2009) Cecilia Gotti et al.   BIOCHEMICAL PHARMACOLOGY

Cognitive Improvement by Activation of α7 Nicotinic Acetylcholine Receptors: From Animal Models to Human Pathophysiology

(2009) Morten Thomsen et al.   CURRENT PHARMACEUTICAL DESIGN

Gating of nicotinic ACh receptors: latest insights into ligand binding and function

(2009) Jerrel L. Yakel   JOURNAL OF PHYSIOLOGY-LONDON

Nicotine binding to brain receptors requires a strong cation–π interaction

(2009) Xinan Xiu et al.   NATURE

Modulatory effects of S 38232, a non α-7 containing nicotine acetylcholine receptor agonist on network activity in the mouse hippocampus

(2009) Laura Lagostena et al.   NEUROPHARMACOLOGY

TC-5214 (S-(+)-Mecamylamine): A Neuronal Nicotinic Receptor Modulator with Antidepressant Activity

(2008) Patrick M. Lippiello et al.   CNS Neuroscience & Therapeutics

Allosteric Modulators of the α7 Nicotinic Acetylcholine Receptor

(2008) Ramin Faghih et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nicotinic receptors, allosteric proteins and medicine

(2008) Jean-Pierre Changeux et al.   TRENDS IN MOLECULAR MEDICINE

Region-specific effects ofN,N′-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopaminein vivo

(2007) S Rahman et al.   BRITISH JOURNAL OF PHARMACOLOGY