Rebuilding a better home for transplanted islets

Innovative encapsulation platform based on pancreatic extracellular matrix achieve substantial insulin delivery

(2017) D. Chaimov et al.   JOURNAL OF CONTROLLED RELEASE

ECM-based macroporous sponges release essential factors to support the growth of hematopoietic cells

(2017) Neta Soffer-Tsur et al.   JOURNAL OF CONTROLLED RELEASE

Modular tissue engineering for the vascularization of subcutaneously transplanted pancreatic islets

(2017) Alexander E. Vlahos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Culture of iPSCs Derived Pancreatic β-Like Cells In Vitro Using Decellularized Pancreatic Scaffolds: A Preliminary Trial

(2017) Jian Wan et al.   Biomed Research International

Cold-perfusion decellularization of whole-organ porcine pancreas supports human fetal pancreatic cell attachment and expression of endocrine and exocrine markers

(2017) Erik Elebring et al.   Journal of Tissue Engineering

Engineering an endocrine Neo-Pancreas by repopulation of a decellularized rat pancreas with islets of Langerhans

(2017) H. Napierala et al.   Scientific Reports

Key Matrix Proteins Within the Pancreatic Islet Basement Membrane Are Differentially Digested During Human Islet Isolation

(2016) S. E. Cross et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Rapid Restoration of Vascularity and Oxygenation in Mouse and Human Islets Transplanted to Omentum May Contribute to Their Superior Function Compared to Intraportally Transplanted Islets

(2016) D. Espes et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The Human Pancreas as a Source of Protolerogenic Extracellular Matrix Scaffold for a New-generation Bioartificial Endocrine Pancreas

(2016) Andrea Peloso et al.   ANNALS OF SURGERY

Progress and challenges in macroencapsulation approaches for type 1 diabetes (T1D) treatment: Cells, biomaterials, and devices

(2016) Shang Song et al.   BIOTECHNOLOGY AND BIOENGINEERING

Closing in on Mass Production of Mature Human Beta Cells

(2016) Timothy J. Kieffer   Cell Stem Cell

Advances in islet encapsulation technologies

(2016) Tejal Desai et al.   NATURE REVIEWS DRUG DISCOVERY

Endocrine pancreas engineered using porcine islets and partial pancreatic scaffolds

(2016) Yusuke Katsuki et al.   PANCREATOLOGY

Secretome of Olfactory Mucosa Mesenchymal Stem Cell, a Multiple Potential Stem Cell

(2016) Lite Ge et al.   Stem Cells International

Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

(2015) H. A. Russ et al.   EMBO JOURNAL

A prevascularized subcutaneous device-less site for islet and cellular transplantation

(2015) Andrew R Pepper et al.   NATURE BIOTECHNOLOGY

3D Culture of MIN-6 Cells on Decellularized Pancreatic Scaffold: In Vitro and In Vivo Study

(2015) Di Wu et al.   Biomed Research International

Efficient Generation of NKX6-1+ Pancreatic Progenitors from Multiple Human Pluripotent Stem Cell Lines

(2015) M. Cristina Nostro et al.   Stem Cell Reports

Natural Scaffolds for Renal Differentiation of Human Embryonic Stem Cells for Kidney Tissue Engineering

(2015) Cynthia A. Batchelder et al.   PLoS One

Long-Term Allogeneic Islet Graft Survival in Prevascularized Subcutaneous Sites Without Immunosuppressive Treatment

(2014) N. M. Luan et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Generation of Functional Human Pancreatic β Cells In Vitro

(2014) Felicia W. Pagliuca et al.   CELL

Decellularized scaffolds as a platform for bioengineered organs

(2014) Luis F. Tapias et al.   Current Opinion in Organ Transplantation

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

(2014) Alireza Rezania et al.   NATURE BIOTECHNOLOGY

Porcine pancreas extracellular matrix as a platform for endocrine pancreas bioengineering

(2013) Sayed-Hadi Mirmalek-Sani et al.   BIOMATERIALS

Perfusion-decellularized pancreas as a natural 3D scaffold for pancreatic tissue and whole organ engineering

(2013) Saik-Kia Goh et al.   BIOMATERIALS

Extracellular Matrix-Mediated Differentiation of Human Embryonic Stem Cells: Differentiation to Insulin-Secreting Beta Cells

(2013) Karthikeyan Narayanan et al.   TISSUE ENGINEERING PART A

Improvement in Outcomes of Clinical Islet Transplantation: 1999-2010

(2012) F. B. Barton et al.   DIABETES CARE

An overview of tissue and whole organ decellularization processes

(2011) Peter M. Crapo et al.   BIOMATERIALS

Long-term in vitro human pancreatic islet culture using three-dimensional microfabricated scaffolds

(2010) Jamal T. Daoud et al.   BIOMATERIALS

The extracellular matrix at a glance

(2010) C. Frantz et al.   JOURNAL OF CELL SCIENCE

Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix

(2010) Basak E Uygun et al.   NATURE MEDICINE

Preservation of Islet Survival by Upregulating α3 Integrin Signaling: The Importance of 3-Dimensional Islet Culture in Basement Membrane Extract

(2010) Y. Zhao et al.   TRANSPLANTATION PROCEEDINGS

The effect of extracellular matrix components on the preservation of human islet function in vitro

(2009) Jamal Daoud et al.   BIOMATERIALS

Extracellular Matrix in Pancreatic Islets: Relevance to Scaffold Design and Transplantation

(2009) John C. Stendahl et al.   CELL TRANSPLANTATION

Preparation and rheological characterization of a gel form of the porcine urinary bladder matrix

(2008) Donald O. Freytes et al.   BIOMATERIALS

Hydrogel encapsulation environments functionalized with extracellular matrix interactions increase islet insulin secretion

(2008) Laney M. Weber et al.   MATRIX BIOLOGY