Modulation of Intestinal Immune and Barrier Functions by Vitamin A: Implications for Current Understanding of Malnutrition and Enteric Infections in Children

Vitamin A and Retinoic Acid Exhibit Protective Effects on Necrotizing Enterocolitis by Regulating Intestinal Flora and Enhancing the Intestinal Epithelial Barrier

(2018) Sa Xiao et al.   ARCHIVES OF MEDICAL RESEARCH

Retinoic acid elicits a coordinated expression of gut homing markers on T lymphocytes of Zambian men receiving oral Vivotif, but not Rotarix, Dukoral or OPVERO vaccines

(2018) Mpala Mwanza-Lisulo et al.   VACCINE

Should universal distribution of high dose vitamin A to children cease?

(2018) JB Mason et al.   BMJ-British Medical Journal

Should universal distribution of high dose vitamin A to children cease?

(2018) JB Mason et al.   BMJ-British Medical Journal

IL-22 Increases Permeability of Intestinal Epithelial Tight Junctions by Enhancing Claudin-2 Expression

(2017) Yaya Wang et al.   JOURNAL OF IMMUNOLOGY

Estimates of global, regional, and national morbidity, mortality, and aetiologies of diarrhoeal diseases: a systematic analysis for the Global Burden of Disease Study 2015

(2017) Christopher Troeger et al.   LANCET INFECTIOUS DISEASES

The effects of micronutrient deficiencies on bacterial species from the human gut microbiota

(2017) Matthew C. Hibberd et al.   Science Translational Medicine

Retinoic Acid Improves Incidence and Severity of Necrotizing Enterocolitis by Lymphocyte Balance Restitution and Repopulation of LGR5+ Intestinal Stem Cells

(2017) Diego F. Niño et al.   SHOCK

Retinoic Acid and Its Role in Modulating Intestinal Innate Immunity

(2017) Paulo Czarnewski et al.   Nutrients

Genetic Variations Associated with Vitamin A Status and Vitamin A Bioavailability

(2017) Patrick Borel et al.   Nutrients

Biomarkers of Nutrition for Development (BOND)—Vitamin A Review

(2016) Sherry A Tanumihardjo et al.   JOURNAL OF NUTRITION

TNFα/IFNγ Mediated Intestinal Epithelial Barrier Dysfunction Is Attenuated by MicroRNA-93 Downregulation of PTK6 in Mouse Colonic Epithelial Cells

(2016) Ricci J. Haines et al.   PLoS One

Association of vitamin D status with incidence of enterotoxigenic, enteropathogenic and enteroaggregativeEscherichia colidiarrhoea in children of urban Bangladesh

(2016) A. M. S. Ahmed et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Retinoic Acid as a Modulator of T Cell Immunity

(2016) Maria Bono et al.   Nutrients

Antiviral effect of vitamin A on norovirus infection via modulation of the gut microbiome

(2016) Heetae Lee et al.   Scientific Reports

Vitamin A Inhibits Development of Dextran Sulfate Sodium-Induced Colitis and Colon Cancer in a Mouse Model

(2016) Isao Okayasu et al.   Biomed Research International

Restoring Retinoic Acid Attenuates Intestinal Inflammation and Tumorigenesis in APCMin/+ Mice

(2016) H. L. Penny et al.   Cancer Immunology Research

Environmental Enteropathy: Elusive but Significant Subclinical Abnormalities in Developing Countries

(2016) Koji Watanabe et al.   EBioMedicine

Biomarkers of Environmental Enteropathy, Inflammation, Stunting, and Impaired Growth in Children in Northeast Brazil

(2016) Richard L. Guerrant et al.   PLoS One

Undernutrition, Vitamin A and Iron Deficiency Are Associated with Impaired Intestinal Mucosal Permeability in Young Bangladeshi Children Assessed by Lactulose/Mannitol Test

(2016) Md. Iqbal Hossain et al.   PLoS One

Environmental Enteric Dysfunction: An Overview

(2015) Rosie J. Crane et al.   FOOD AND NUTRITION BULLETIN

Vitamin A-Deficient Hosts Become Nonsymptomatic Reservoirs of Escherichia coli-Like Enteric Infections

(2015) Kaitlin L. McDaniel et al.   INFECTION AND IMMUNITY

An enigma: why vitamin A supplementation does not always reduce mortality even though vitamin A deficiency is associated with increased mortality

(2015) Christine S Benn et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Toll-like receptor 4–mediated lymphocyte influx induces neonatal necrotizing enterocolitis

(2015) Charlotte E. Egan et al.   JOURNAL OF CLINICAL INVESTIGATION

Retinoic Acid Imprints a Mucosal-like Phenotype on Dendritic Cells with an Increased Ability To Fuel HIV-1 Infection

(2015) Natalia Guerra-Pérez et al.   JOURNAL OF IMMUNOLOGY

Vitamin A induces inhibitory histone methylation modifications and down-regulates trained immunity in human monocytes

(2015) Rob J. W. Arts et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neonatal vitamin A supplementation: time to move on

(2015) Batool A Haider et al.   LANCET

Effect of early neonatal vitamin A supplementation on mortality during infancy in Ghana (Neovita): a randomised, double-blind, placebo-controlled trial

(2015) Karen M Edmond et al.   LANCET

Effect of neonatal vitamin A supplementation on mortality in infants in Tanzania (Neovita): a randomised, double-blind, placebo-controlled trial

(2015) Honorati Masanja et al.   LANCET

Efficacy of early neonatal supplementation with vitamin A to reduce mortality in infancy in Haryana, India (Neovita): a randomised, double-blind, placebo-controlled trial

(2015) Sarmila Mazumder et al.   LANCET

Vitamin A exerts its antiinflammatory activities in colitis through preservation of mitochondrial activity

(2015) Ram Reifen et al.   NUTRITION

Retinoic Acid Can Exacerbate T Cell Intrinsic TLR2 Activation to Promote Tolerance

(2015) Vivien Nguyen et al.   PLoS One

Vitamin A deficiency: slow progress towards elimination

(2015) Davidson H Hamer et al.   Lancet Global Health

Trends and mortality effects of vitamin A deficiency in children in 138 low-income and middle-income countries between 1991 and 2013: a pooled analysis of population-based surveys

(2015) Gretchen A Stevens et al.   Lancet Global Health

Pathogen-specific burdens of community diarrhoea in developing countries: a multisite birth cohort study (MAL-ED)

(2015) James A Platts-Mills et al.   Lancet Global Health

The Treg/Th17 Axis: A Dynamic Balance Regulated by the Gut Microbiome

(2015) Sara Omenetti et al.   Frontiers in Immunology

STRA6 is critical for cellular vitamin A uptake and homeostasis

(2014) Jaume Amengual et al.   HUMAN MOLECULAR GENETICS

Retinoid Levels Influence Enterohemorrhagic Escherichia coli Infection and Shiga Toxin 2 Susceptibility in Mice

(2014) Gabriel Cabrera et al.   INFECTION AND IMMUNITY

Vitamin A policies need rethinking

(2014) John Mason et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Modulation of T Cell and Innate Immune Responses by Retinoic Acid

(2014) M. Raverdeau et al.   JOURNAL OF IMMUNOLOGY

Vitamin A Deficiency Is Associated with Gastrointestinal and Respiratory Morbidity in School-Age Children1–3

(2014) Kathryn A. Thornton et al.   JOURNAL OF NUTRITION

Two Different Doses of Supplemental Vitamin A Did Not Affect Mortality of Normal-Birth-Weight Neonates in Guinea-Bissau in a Randomized Controlled Trial

(2014) Christine S. Benn et al.   JOURNAL OF NUTRITION

Unique lamina propria stromal cells imprint the functional phenotype of mucosal dendritic cells

(2014) I Vicente-Suarez et al.   Mucosal Immunology

Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells

(2014) G Bakdash et al.   Mucosal Immunology

Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity

(2014) Serge A. van de Pavert et al.   NATURE

Does vitamin A supplementation protect schoolchildren from acquiring soil-transmitted helminthiasis? A randomized controlled trial

(2014) Hesham M Al-Mekhlafi et al.   Parasites & Vectors

High-dose Vitamin A With Vaccination After 6 Months of Age: A Randomized Trial

(2014) A. B. Fisker et al.   PEDIATRICS

Vitamin A Supplementation in Early Life Enhances the Intestinal Immune Response of Rats with Gestational Vitamin A Deficiency by Increasing the Number of Immune Cells

(2014) Xia Liu et al.   PLoS One

Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions

(2014) L. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serum Amyloid A proteins take retinol for a ride

(2014) Daria Esterházy et al.   TRENDS IN IMMUNOLOGY

Undernutrition, the Acute Phase Response to Infection, and Its Effects on Micronutrient Status Indicators

(2014) Kara A. Bresnahan et al.   Advances in Nutrition

Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection

(2014) Mehabaw G Derebe et al.   eLife

Preventing Blindness and Saving Lives

(2014) Alfred Sommer   JAMA Ophthalmology

Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation

(2013) Lisa A. Mielke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Prenatally Acquired Vitamin A Deficiency Alters Innate Immune Responses to Human Rotavirus in a Gnotobiotic Pig Model

(2013) A. N. Vlasova et al.   JOURNAL OF IMMUNOLOGY

Maternal and child undernutrition and overweight in low-income and middle-income countries

(2013) Robert E Black et al.   LANCET

Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid

(2013) J CJ Martin et al.   Mucosal Immunology

Probiotics and colostrum/milk differentially affect neonatal humoral immune responses to oral rotavirus vaccine

(2013) Kuldeep S. Chattha et al.   VACCINE

Apolipoprotein E4 influences growth and cognitive responses to micronutrient supplementation in shantytown children from northeast Brazil

(2012) SS Mitter et al.   Clinics

The impoverished gut—a triple burden of diarrhoea, stunting and chronic disease

(2012) Richard L. Guerrant et al.   Nature Reviews Gastroenterology & Hepatology

A Comparison of Gene Expression Responses in Rat Whole Embryo Culture and In Vivo: Time-Dependent Retinoic Acid-Induced Teratogenic Response

(2012) Joshua F. Robinson et al.   TOXICOLOGICAL SCIENCES

Vitamin A supplementation modifies the association between mucosal innate and adaptive immune responses and resolution of enteric pathogen infections

(2011) K. Z. Long et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Contribution of Enteric Infection, Altered Intestinal Barrier Function, and Maternal Malnutrition to Infant Malnutrition in Bangladesh

(2011) D. Mondal et al.   CLINICAL INFECTIOUS DISEASES

All-Trans Retinoic Acid Promotes TGF-β-Induced Tregs via Histone Modification but Not DNA Demethylation on Foxp3 Gene Locus

(2011) Ling Lu et al.   PLoS One

Vitamin A: A multifunctional tool for development

(2011) Juliana Gutierrez-Mazariegos et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Intestinal CD103+ dendritic cells: master regulators of tolerance?

(2011) Charlotte L. Scott et al.   TRENDS IN IMMUNOLOGY

Glyphosate-Based Herbicides Produce Teratogenic Effects on Vertebrates by Impairing Retinoic Acid Signaling

(2010) Alejandra Paganelli et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Downregulation of Th17 Cells in the Small Intestine by Disruption of Gut Flora in the Absence of Retinoic Acid

(2010) H.-R. Cha et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: All-Trans Retinoic Acid Sustains the Stability and Function of Natural Regulatory T Cells in an Inflammatory Milieu

(2010) X. Zhou et al.   JOURNAL OF IMMUNOLOGY

Carotenoids, Retinol, and Intestinal Barrier Function in Children From Northeastern Brazil

(2010) Milena M Vieira et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Effects of Vitamin A Supplementation on Intestinal Barrier Function, Growth, Total Parasitic, and Specific Giardia spp Infections in Brazilian Children: A Prospective Randomized, Double-blind, Placebo-controlled Trial

(2010) Aldo AM Lima et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Newborn Vitamin A Supplementation Reduced Infant Mortality in Rural Bangladesh

(2008) R. D.W. Klemm et al.   PEDIATRICS