Genetic Variations Associated with Vitamin A Status and Vitamin A Bioavailability

Overview of carotenoid bioavailability determinants: From dietary factors to host genetic variations

(2017) Charles Desmarchelier et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Common SNP rs6564851 in the BCO1 Gene Affects the Circulating Levels of β-Carotene and the Daily Intake of Carotenoids in Healthy Japanese Women

(2017) Suemi Yabuta et al.   PLoS One

PNPLA3 gene in liver diseases

(2016) Eric Trépo et al.   JOURNAL OF HEPATOLOGY

Mechanisms of selective delivery of xanthophylls to retinal pigment epithelial cells by human lipoproteins

(2016) Sara E. Thomas et al.   JOURNAL OF LIPID RESEARCH

Biomarkers of Nutrition for Development (BOND)—Vitamin A Review

(2016) Sherry A Tanumihardjo et al.   JOURNAL OF NUTRITION

Vitamin A deficiency due to bi-allelic mutation of RBP4: There’s more to it than meets the eye

(2016) Kamron N. Khan et al.   OPHTHALMIC GENETICS

High provitamin A carotenoid serum concentrations, elevated retinyl esters, and saturated retinol-binding protein in Zambian preschool children are consistent with the presence of high liver vitamin A stores

(2015) Stephanie Mondloch et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Cellular localization of β-carotene 15,15′ oxygenase-1 (BCO1) and β-carotene 9′,10′ oxygenase-2 (BCO2) in rat liver and intestine

(2015) Shiva Raghuvanshi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells

(2015) Ulrike Taschler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Nuclear and extranuclear effects of vitamin A

(2015) Madina Iskakova et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

The Genetic Variant I148M inPNPLA3Is Associated With Increased Hepatic Retinyl-Palmitate Storage in Humans

(2015) Marketa Kovarova et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

PNPLA3 I148M Variant Influences Circulating Retinol in Adults with Nonalcoholic Fatty Liver Disease or Obesity

(2015) Alison Mondul et al.   JOURNAL OF NUTRITION

A Combination of Single-Nucleotide Polymorphisms Is Associated with Interindividual Variability in Dietary β-Carotene Bioavailability in Healthy Men

(2015) Patrick Borel et al.   JOURNAL OF NUTRITION

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Enterocyte fatty acid-binding proteins (FABPs): Different functions of liver and intestinal FABPs in the intestine

(2015) Angela M. Gajda et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells

(2014) Carlo Pirazzi et al.   HUMAN MOLECULAR GENETICS

Vitamin A policies need rethinking

(2014) John Mason et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

β-Lactoglobulin as a Vector for β-Carotene Food Fortification

(2014) Azza Mensi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Intestinal Scavenger Receptors Are Involved in Vitamin K1Absorption

(2014) Aurélie Goncalves et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Human Enzyme That Converts Dietary Provitamin A Carotenoids to Vitamin A Is a Dioxygenase

(2014) Carlo dela Seña et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Postprandial Chylomicron Triacylglycerol Response to Dietary Fat in Healthy Male Adults Is Significantly Explained by a Combination of Single Nucleotide Polymorphisms in Genes Involved in Triacylglycerol Metabolism

(2014) Charles Desmarchelier et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function

(2013) Piero Pingitore et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Genetics and Diet Regulate Vitamin A Production via the Homeobox Transcription Factor ISX

(2013) Glenn P. Lobo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two Carotenoid Oxygenases Contribute to Mammalian Provitamin A Metabolism

(2013) Jaume Amengual et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substrate Specificity of Purified Recombinant Human β-Carotene 15,15′-Oxygenase (BCO1)

(2013) Carlo dela Seña et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Retinol and retinyl esters: biochemistry and physiology

(2013) Sheila M. O'Byrne et al.   JOURNAL OF LIPID RESEARCH

CD36 and SR-BI Are Involved in Cellular Uptake of Provitamin A Carotenoids by Caco-2 and HEK Cells, and Some of Their Genetic Variants Are Associated with Plasma Concentrations of These Micronutrients in Humans

(2013) Patrick Borel et al.   JOURNAL OF NUTRITION

Imputation of Variants from the 1000 Genomes Project Modestly Improves Known Associations and Can Identify Low-frequency Variant - Phenotype Associations Undetected by HapMap Based Imputation

(2013) Andrew R. Wood et al.   PLoS One

PNPLA3 I148M polymorphism and progressive liver disease

(2013) Paola Dongiovanni   WORLD JOURNAL OF GASTROENTEROLOGY

β-Carotene 15,15′-monooxygenase 1 single nucleotide polymorphisms in relation to plasma carotenoid and retinol concentrations in women of European descent

(2012) Sara J Hendrickson et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Dietary surveys indicate vitamin intakes below recommendations are common in representative Western countries

(2012) Barbara Troesch et al.   BRITISH JOURNAL OF NUTRITION

Lecithin:Retinol Acyltransferase Is Critical for Cellular Uptake of Vitamin A from Serum Retinol-binding Protein

(2012) Jaume Amengual et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Liver Retinol Transporter and Receptor for Serum Retinol-binding Protein (RBP4)

(2012) Philomena Alapatt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro

(2012) Carlo Pirazzi et al.   JOURNAL OF HEPATOLOGY

Intestinal DGAT1 deficiency reduces postprandial triglyceride and retinyl ester excursions by inhibiting chylomicron secretion and delaying gastric emptying

(2012) Gene P. Ables et al.   JOURNAL OF LIPID RESEARCH

Mechanisms involved in the intestinal absorption of dietary vitamin A and provitamin A carotenoids

(2011) Earl H. Harrison   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Respective contributions of intestinal Niemann-Pick C1-like 1 and scavenger receptor class B type I to cholesterol and tocopherol uptake: in vivo v. in vitro studies

(2011) Emmanuelle Reboul et al.   BRITISH JOURNAL OF NUTRITION

Genome-wide association study of circulating retinol levels

(2011) Alison M. Mondul et al.   HUMAN MOLECULAR GENETICS

Single Nucleotide Polymorphisms Upstream from the β-Carotene 15,15'-Monoxygenase Gene Influence Provitamin A Conversion Efficiency in Female Volunteers

(2011) Georg Lietz et al.   JOURNAL OF NUTRITION

The contribution of β-carotene to vitamin A supply of humans

(2011) Daniela Weber et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Proteins involved in uptake, intracellular transport and basolateral secretion of fat-soluble vitamins and carotenoids by mammalian enterocytes

(2011) Emmanuelle Reboul et al.   PROGRESS IN LIPID RESEARCH

Hepatic stellate cells are an important cellular site for β-carotene conversion to retinoid

(2010) Igor Shmarakov et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Update on genetics of postprandial lipemia

(2010) Pablo Perez-Martinez et al.   ATHEROSCLEROSIS SUPPLEMENTS

ISX is a retinoic acid-sensitive gatekeeper that controls intestinal β,β-carotene absorption and vitamin A production

(2010) Glenn P. Lobo et al.   FASEB JOURNAL

The Micronutrient Genomics Project: a community-driven knowledge base for micronutrient research

(2010) Ben van Ommen et al.   Genes and Nutrition

Lecithin: retinol acyltransferase protein is distributed in both hepatic stellate cells and endothelial cells of normal rodent and human liver

(2010) Keisuke Nagatsuma et al.   LIVER INTERNATIONAL

Common Variation in the β-Carotene 15,15′-Monooxygenase 1 Gene Affects Circulating Levels of Carotenoids: A Genome-wide Association Study

(2009) Luigi Ferrucci et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The metabolism of triglyceride-rich lipoproteins revisited: New players, new insight

(2009) Geesje M. Dallinga-Thie et al.   ATHEROSCLEROSIS

Hormone-sensitive lipase (HSL) is also a retinyl ester hydrolase: evidence from mice lacking HSL

(2009) Kristoffer Ström et al.   FASEB JOURNAL

A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis

(2009) Shaoqing He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human fasting plasma concentrations of vitamin E and carotenoids, and their association with genetic variants in apo C-III, cholesteryl ester transfer protein, hepatic lipase, intestinal fatty acid binding protein and microsomal triacylglycerol transfer protein

(2008) Patrick Borel et al.   BRITISH JOURNAL OF NUTRITION

Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers

(2008) W. C. Leung et al.   FASEB JOURNAL

The Molecular Basis of Retinoid Absorption

(2008) Nuttaporn Wongsiriroj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Xanthophylls are preferentially taken up compared with β-carotene by retinal cells via a SRBI-dependent mechanism,

(2008) Alexandrine During et al.   JOURNAL OF LIPID RESEARCH