Short-Term Fish Oil Treatment Changes the Composition of Phospholipids While Not Affecting the Expression of Mfsd2a Omega-3 Transporter in the Brain and Liver of the 5xFAD Mouse Model of Alzheimer’s Disease

Fish oil feeding attenuates neuroinflammatory gene expression without concomitant changes in brain eicosanoids and docosanoids in a mouse model of Alzheimer’s disease

(2018) Kathryn E. Hopperton et al.   BRAIN BEHAVIOR AND IMMUNITY

Dietary Vitamin E Status Dictates Oxidative Stress Outcomes by Modulating Effects of Fish Oil Supplementation in Alzheimer Disease Model APPswe/PS1dE9 Mice

(2018) Shengqi Dong et al.   MOLECULAR NEUROBIOLOGY

Endogenous Conversion of Omega-6 into Omega-3 Fatty Acids Improves Neuropathology in an Animal Model of Alzheimer's Disease

(2018) Meryem Lebbadi et al.   JOURNAL OF ALZHEIMERS DISEASE

The Effects of Long-Term Omega-3 Fatty Acid Supplementation on Cognition and Alzheimer's Pathology in Animal Models of Alzheimer's Disease: A Systematic Review and Meta-Analysis

(2018) Carlijn R. Hooijmans et al.   JOURNAL OF ALZHEIMERS DISEASE

Nonamyloidogenic processing of amyloid beta precursor protein is associated with retinal function improvement in aging male APP swe /PS1ΔE9 mice

(2017) Sandrine Joly et al.   NEUROBIOLOGY OF AGING

Fatty acid transporting proteins: Roles in brain development, aging, and stroke

(2017) Wenting Zhang et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

APP Function and Lipids: A Bidirectional Link

(2017) Marcus O. W. Grimm et al.   Frontiers in Molecular Neuroscience

Immunoproteasome deficiency alters microglial cytokine response and improves cognitive deficits in Alzheimer’s disease-like APPPS1 mice

(2017) Lisa K. Wagner et al.   Acta Neuropathologica Communications

Dietary DHA supplementation causes selective changes in phospholipids from different brain regions in both wild type mice and the Tg2576 mouse model of Alzheimer's disease

(2016) Cécile Bascoul-Colombo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Dietary arachidonic acid as a risk factor for age-associated neurodegenerative diseases: Potential mechanisms

(2016) Mélanie H. Thomas et al.   BIOCHIMIE

Docosahexaenoic acid: one molecule diverse functions

(2016) Michio Hashimoto et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

N-3 polyunsaturated fatty acids in animal models with neuroinflammation: An update

(2016) Marc-Olivier Trépanier et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A Diet Rich in Docosahexaenoic Acid Restores Liver Arachidonic Acid and Docosahexaenoic Acid Concentrations in Mice Homozygous for the Human Apolipoprotein E ε4 Allele

(2016) Raphaël Chouinard-Watkins et al.   JOURNAL OF NUTRITION

The unfolded protein response in the therapeutic effect of hydroxy-DHA against Alzheimer’s disease

(2015) Manuel Torres et al.   APOPTOSIS

Omega-3 Fatty Acids Augment the Actions of Nuclear Receptor Agonists in a Mouse Model of Alzheimer's Disease

(2015) B. T. Casali et al.   JOURNAL OF NEUROSCIENCE

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Dietary DHA supplementation in an APP/PS1 transgenic rat model of AD reduces behavioral and Aβ pathology and modulates Aβ oligomerization

(2015) Edmond Teng et al.   NEUROBIOLOGY OF DISEASE

Neuroinflammatory processes in cognitive disorders: Is there a role for flavonoids and n-3 polyunsaturated fatty acids in counteracting their detrimental effects?

(2015) David Vauzour et al.   NEUROCHEMISTRY INTERNATIONAL

Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques

(2015) Carlo Condello et al.   Nature Communications

Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA

(2015) Simon C. Dyall   Frontiers in Aging Neuroscience

The effect of natural and synthetic fatty acids on membrane structure, microdomain organization, cellular functions and human health

(2014) Maitane Ibarguren et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Membrane lipid modifications and therapeutic effects mediated by hydroxydocosahexaenoic acid on Alzheimer's disease

(2014) Manuel Torres et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer’s disease

(2014) Véréna Landel et al.   Molecular Neurodegeneration

Mfsd2a is critical for the formation and function of the blood–brain barrier

(2014) Ayal Ben-Zvi et al.   NATURE

Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid

(2014) Long N. Nguyen et al.   NATURE

Polyunsaturated fatty acids and their metabolites in brain function and disease

(2014) Richard P. Bazinet et al.   NATURE REVIEWS NEUROSCIENCE

Disruption of Amyloid Plaques Integrity Affects the Soluble Oligomers Content from Alzheimer Disease Brains

(2014) Sebastian Jimenez et al.   PLoS One

A Nutrient Combination that Can Affect Synapse Formation

(2014) Richard Wurtman   Nutrients

Partitioning of liquid-ordered/liquid-disordered membrane microdomains induced by the fluidifying effect of 2-hydroxylated fatty acid derivatives

(2013) Maitane Ibarguren et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cognitive recovery and restoration of cell proliferation in the dentate gyrus in the 5XFAD transgenic mice model of Alzheimer’s disease following 2-hydroxy-DHA treatment

(2013) Maria A. Fiol-deRoque et al.   BIOGERONTOLOGY

Special lipid-based diets alleviate cognitive deficits in the APPswe/PS1dE9 transgenic mouse model of Alzheimer's disease independent of brain amyloid deposition

(2013) Hennariikka Koivisto et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis

(2013) Melanie Kahle et al.   Molecular Metabolism

Resolvins D1, D2, and Other Mediators of Self-Limited Resolution of Inflammation in Human Blood following n-3 Fatty Acid Supplementation

(2012) E. Mas et al.   CLINICAL CHEMISTRY

Short-Term Long Chain Omega3 Diet Protects from Neuroinflammatory Processes and Memory Impairment in Aged Mice

(2012) Virginie F. Labrousse et al.   PLoS One

Major Facilitator Superfamily Domain-Containing Protein 2a (MFSD2A) Has Roles in Body Growth, Motor Function, and Lipid Metabolism

(2012) Justin H. Berger et al.   PLoS One

Docosahexaenoic Acid Reduces Amyloid β Production via Multiple Pleiotropic Mechanisms

(2011) Marcus O. W. Grimm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parietal cortex matters in Alzheimer's disease: An overview of structural, functional and metabolic findings

(2011) Heidi I.L. Jacobs et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

DHA Improves Cognition and Prevents Dysfunction of Entorhinal Cortex Neurons in 3xTg-AD Mice

(2011) Dany Arsenault et al.   PLoS One

Phospholipase A2 and arachidonic acid in Alzheimer's disease

(2010) Rene O. Sanchez-Mejia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Deficient Liver Biosynthesis of Docosahexaenoic Acid Correlates with Cognitive Impairment in Alzheimer's Disease

(2010) Giuseppe Astarita et al.   PLoS One

Short-term docosapentaenoic acid (22 : 5 n-3) supplementation increases tissue docosapentaenoic acid, DHA and EPA concentrations in rats

(2009) Gunveen Kaur et al.   BRITISH JOURNAL OF NUTRITION

 -Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin

(2009) Q.-L. Ma et al.   JOURNAL OF NEUROSCIENCE

DHA diet reduces AD pathology in young APPswe/PS1ΔE9 transgenic mice: Possible gender effects

(2009) Sylvia E. Perez et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

(2008) Melanie Meyer-Luehmann et al.   NATURE

DHA and cholesterol containing diets influence Alzheimer-like pathology, cognition and cerebral vasculature in APPswe/PS1dE9 mice

(2008) C.R. Hooijmans et al.   NEUROBIOLOGY OF DISEASE