Mesenchymal Stem/Stromal Cells in Liver Fibrosis: Recent Findings, Old/New Caveats and Future Perspectives
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Title
Mesenchymal Stem/Stromal Cells in Liver Fibrosis: Recent Findings, Old/New Caveats and Future Perspectives
Authors
Keywords
Cirrhosis, Mesenchymal stem cells, Neural crest, Hepatocyte-like cells, IGF-I, Biosafety, Cell source, Biodistribution, Mechanisms
Journal
Stem Cell Reviews and Reports
Volume 11, Issue 4, Pages 586-597
Publisher
Springer Nature
Online
2015-03-29
DOI
10.1007/s12015-015-9585-9
References
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Note: Only part of the references are listed.- Use of mesenchymal stem cells to treat liver fibrosis: Current situation and future prospects
- (2015) Silvia Berardis et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Immunological basis of stem cell therapy in liver diseases
- (2014) Lina Cui et al. Expert Review of Clinical Immunology
- Glial origin of mesenchymal stem cells in a tooth model system
- (2014) Nina Kaukua et al. NATURE
- Origin of myofibroblasts in the fibrotic liver in mice
- (2014) K. Iwaisako et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Concise Review: Therapeutic Potential of Mesenchymal Stem Cells for the Treatment of Acute Liver Failure and Cirrhosis
- (2014) Vladislav Volarevic et al. STEM CELLS
- The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem cell niche function
- (2014) Joan Isern et al. eLife
- Management of Fibrosis: The Mesenchymal Stromal Cells Breakthrough
- (2014) Benoît Usunier et al. Stem Cells International
- Perivascular support of human hematopoietic stem/progenitor cells
- (2013) M. Corselli et al. BLOOD
- Mesenchymal Stromal Cells: Sensors and Switchers of Inflammation
- (2013) Maria Ester Bernardo et al. Cell Stem Cell
- Notch signaling regulates CXCR4 expression and the migration of mesenchymal stem cells
- (2013) Juan Xie et al. CELLULAR IMMUNOLOGY
- Immunological characterization of multipotent mesenchymal stromal cells—The International Society for Cellular Therapy (ISCT) working proposal
- (2013) Mauro Krampera et al. CYTOTHERAPY
- CXCR4 transfection of cord blood mesenchymal stromal cells with the use of cationic liposome enhances their migration toward stromal cell–derived factor-1
- (2013) Leah A. Marquez-Curtis et al. CYTOTHERAPY
- Uptake and delivery of antigens by mesenchymal stromal cells
- (2013) Luis Ignacio Sánchez-Abarca et al. CYTOTHERAPY
- Mesenchymal stromal/stem cells markers in the human bone marrow
- (2013) Valeria Rasini et al. CYTOTHERAPY
- Manufacturing mesenchymal stromal cells for phase I clinical trials
- (2013) Patrick J. Hanley et al. CYTOTHERAPY
- Risk of tumorigenicity in mesenchymal stromal cell–based therapies—Bridging scientific observations and regulatory viewpoints
- (2013) Lisbeth Barkholt et al. CYTOTHERAPY
- How important is differentiation in the therapeutic effect of mesenchymal stromal cells in liver disease?
- (2013) Hanyu Wang et al. CYTOTHERAPY
- A xeno-free culture method that enhances Wharton's jelly mesenchymal stromal cell culture efficiency over traditional animal serum–supplemented cultures
- (2013) Suphakde Julavijitphong et al. CYTOTHERAPY
- Transgenerational Inheritance of Increased Fat Depot Size, Stem Cell Reprogramming, and Hepatic Steatosis Elicited by Prenatal Exposure to the Obesogen Tributyltin in Mice
- (2013) Raquel Chamorro-García et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Detection of spontaneous tumorigenic transformation during culture expansion of human mesenchymal stromal cells
- (2013) Qiuwei Pan et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Adipose tissue-derived stem cells as a regenerative therapy for a mouse steatohepatitis-induced cirrhosis model
- (2013) Akihiro Seki et al. HEPATOLOGY
- Mesenchymal stem cells alleviate bacteria-induced liver injury in mice by inducing regulatory dendritic cells
- (2013) Yi Zhang et al. HEPATOLOGY
- M2-like macrophages are responsible for collagen degradation through a mannose receptor–mediated pathway
- (2013) Daniel H. Madsen et al. JOURNAL OF CELL BIOLOGY
- A pilot study of umbilical cord-derived mesenchymal stem cell transfusion in patients with primary biliary cirrhosis
- (2013) Lifeng Wang et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Exosomes in the pathogenesis, diagnostics and therapeutics of liver diseases
- (2013) Anatoliy I. Masyuk et al. JOURNAL OF HEPATOLOGY
- Innate Immune Cell-Derived Microparticles Facilitate Hepatocarcinoma Metastasis by Transferring Integrin M 2 to Tumor Cells
- (2013) J. Ma et al. JOURNAL OF IMMUNOLOGY
- Autologous bone marrow-derived mesenchymal stem cell transplantation promotes liver regeneration after portal vein embolization in cirrhotic rats
- (2013) Tingjun Li et al. JOURNAL OF SURGICAL RESEARCH
- Transplantation of bone marrow–derived mesenchymal stem cells after regional hepatic irradiation ameliorates thioacetamide-induced liver fibrosis in rats
- (2013) Cun-hua Shao et al. JOURNAL OF SURGICAL RESEARCH
- Mesenchymal stem cells and Interleukin-6 attenuate liver fibrosis in mice
- (2013) Ghazanfar Ali Nasir et al. Journal of Translational Medicine
- Histological improvement following administration of autologous bone marrow-derived mesenchymal stem cells for alcoholic cirrhosis: a pilot study
- (2013) Yoon Ok Jang et al. LIVER INTERNATIONAL
- The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine
- (2013) Paolo Bianco et al. NATURE MEDICINE
- Lack of the Matricellular Protein SPARC (Secreted Protein, Acidic and Rich in Cysteine) Attenuates Liver Fibrogenesis in Mice
- (2013) Catalina Atorrasagasti et al. PLoS One
- In Vivo Tracking and Comparison of the Therapeutic Effects of MSCs and HSCs for Liver Injury
- (2013) Qiang Li et al. PLoS One
- Transplantation of mesenchymal stem cells for the treatment of liver diseases, is there enough evidence?
- (2013) Raphael P.H. Meier et al. Stem Cell Research
- Human Placenta-Derived Mesenchymal Stem Cells Promote Hepatic Regeneration in CCl4-Injured Rat Liver Model via Increased Autophagic Mechanism
- (2013) Jieun Jung et al. STEM CELLS
- Concise review: Clinical programs of stem cell therapies for liver and pancreas
- (2013) Giacomo Lanzoni et al. STEM CELLS
- Human Adipose Tissue Possesses a Unique Population of Pluripotent Stem Cells with Nontumorigenic and Low Telomerase Activities: Potential Implications in Regenerative Medicine
- (2013) Fumitaka Ogura et al. STEM CELLS AND DEVELOPMENT
- Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy
- (2013) J C Estrada et al. Cell Death & Disease
- Production of mesenchymal stromal/stem cells according to good manufacturing practices: a review
- (2013) Luc Sensebé et al. Stem Cell Research & Therapy
- Developing a New Two-Step Protocol to Generate Functional Hepatocytes from Wharton’s Jelly-Derived Mesenchymal Stem Cells under Hypoxic Condition
- (2013) Patcharee Prasajak et al. Stem Cells International
- Multipotent Human Mesenchymal Stromal Cells Mediate Expansion of Myeloid-Derived Suppressor Cells via Hepatocyte Growth Factor/c-Met and STAT3
- (2013) B. Linju Yen et al. Stem Cell Reports
- microRNA-27b suppresses mouse MSC migration to the liver by targeting SDF-1α in vitro
- (2012) Mu-Han Lü et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Characterization ofin vitrocultured bone marrow and adipose tissue-derived mesenchymal stem cells and their ability to express neurotrophic factors
- (2012) Ghorbanian Mohammad Taghi et al. CELL BIOLOGY INTERNATIONAL
- Mesenchymal stem cells restore CCl4-induced liver injury by an antioxidative process
- (2012) Kyung‑Ah Cho et al. CELL BIOLOGY INTERNATIONAL
- Stability of human mesenchymal stem cells duringin vitroculture: considerations for cell therapy
- (2012) R. Binato et al. CELL PROLIFERATION
- Nrf-2 overexpression in mesenchymal stem cells reduces oxidative stress-induced apoptosis and cytotoxicity
- (2012) Mohammad Mohammadzadeh et al. CELL STRESS & CHAPERONES
- Mesenchymal stem cells and neural crest stem cells from adult bone marrow: characterization of their surprising similarities and differences
- (2012) Sabine Wislet-Gendebien et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The aggregate nature of human mesenchymal stromal cells in native bone marrow
- (2012) Naser Ahmadbeigi et al. CYTOTHERAPY
- Human decidua-derived mesenchymal stromal cells differentiate into hepatic-like cells and form functional three-dimensional structures
- (2012) Rafael Bornstein et al. CYTOTHERAPY
- Cryopreservation of umbilical cord mesenchymal cells in xenofree conditions
- (2012) Karen de Lima Prata et al. CYTOTHERAPY
- Role of Environmental Chemicals in Diabetes and Obesity: A National Toxicology Program Workshop Review
- (2012) Kristina A. Thayer et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Expression of Neural Markers by Undifferentiated Rat Mesenchymal Stem Cells
- (2012) Dana Foudah et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Human umbilical cord mesenchymal stem cells improve liver function and ascites in decompensated liver cirrhosis patients
- (2012) Zheng Zhang et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Nitric oxide augments mesenchymal stem cell ability to repair liver fibrosis
- (2012) Gibran Ali et al. Journal of Translational Medicine
- Pre-conditioned mesenchymal stem cells ameliorate renal ischemic injury in rats by augmented survival and engraftment
- (2012) Muhammad Masoud et al. Journal of Translational Medicine
- Effects of two mesenchymal cell populations on hepatocytes and lymphocytes
- (2012) Alejandro Gómez-Aristizábal et al. LIVER TRANSPLANTATION
- Circulating Mesenchymal Stem Cells Microparticles in Patients with Cerebrovascular Disease
- (2012) Suk Jae Kim et al. PLoS One
- HGF and Direct Mesenchymal Stem Cells Contact Synergize to Inhibit Hepatic Stellate Cells Activation through TLR4/NF-kB Pathway
- (2012) Pei-pei Wang et al. PLoS One
- Dynamic microRNA Profiles of Hepatic Differentiated Human Umbilical Cord Lining-Derived Mesenchymal Stem Cells
- (2012) Lina Cui et al. PLoS One
- Adenoviral Transduction of Mesenchymal Stem Cells: In Vitro Responses and In Vivo Immune Responses after Cell Transplantation
- (2012) Oliver Treacy et al. PLoS One
- Relearning the Lessons of Genomic Stability of Human Cells During Expansion in Culture: Implications for Clinical Research
- (2012) Darwin J. Prockop et al. STEM CELLS
- Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Liver Fibrosis
- (2012) Tingfen Li et al. STEM CELLS AND DEVELOPMENT
- The role of immunosuppression of mesenchymal stem cells in tissue repair and tumor growth
- (2012) Zhipeng Han et al. Cell and Bioscience
- Concise Review: Mesenchymal Stem Cells and Translational Medicine: Emerging Issues
- (2012) Guangwen Ren et al. Stem Cells Translational Medicine
- Development and Characterization of a Clinically Compliant Xeno-Free Culture Medium in Good Manufacturing Practice for Human Multipotent Mesenchymal Stem Cells
- (2012) Lucas G. Chase et al. Stem Cells Translational Medicine
- Human Mesenchymal Stem Cell Transfusion Is Safe and Improves Liver Function in Acute-on-Chronic Liver Failure Patients
- (2012) Ming Shi et al. Stem Cells Translational Medicine
- Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion
- (2012) E. Eggenhofer et al. Frontiers in Immunology
- Bone Marrow Mesenchymal Cells: How Do They Contribute to Tissue Repair and Are They Really Stem Cells?
- (2011) Yasumasa Kuroda et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- Methodology and software to detect viral integration site hot-spots
- (2011) Angela P Presson et al. BMC BIOINFORMATICS
- Differentiation of human umbilical cord mesenchymal stem cells into hepatocyte-like cells by hTERT gene transfectionin vitro
- (2011) Xu‑Jing Liang et al. CELL BIOLOGY INTERNATIONAL
- Culture of human mesenchymal stem cells at low oxygen tension improves growth and genetic stability by activating glycolysis
- (2011) J C Estrada et al. CELL DEATH AND DIFFERENTIATION
- Adenovirus-mediated expression of the HO-1 protein within MSCs decreased cytotoxicity and inhibited apoptosis induced by oxidative stresses
- (2011) Pejman Hamedi-Asl et al. CELL STRESS & CHAPERONES
- Epidermal growth factor, basic fibroblast growth factor and platelet-derived growth factor-bb can substitute for fetal bovine serum and compete with human platelet-rich plasma in the ex vivo expansion of mesenchymal stromal cells derived from adipose tissue
- (2011) Katia Chieregato et al. CYTOTHERAPY
- Mesenchymal stromal cells impair the differentiation of CD14++ CD16− CD64+ classical monocytes into CD14++ CD16+ CD64++ activate monocytes
- (2011) Bárbara Du Rocher et al. CYTOTHERAPY
- Therapeutic Implications of Mesenchymal Stem Cells in Liver Injury
- (2011) Maria Ausiliatrice Puglisi et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- New horizons for stem cell therapy in liver disease
- (2011) Stuart J. Forbes et al. JOURNAL OF HEPATOLOGY
- Insulin-like growth factor-I and the liver
- (2011) Karen Bonefeld et al. LIVER INTERNATIONAL
- Mesenchymal Stem/Stromal Cells (MSCs): Role as Guardians of Inflammation
- (2011) Darwin J Prockop et al. MOLECULAR THERAPY
- Transplanted Human Amniotic Membrane-Derived Mesenchymal Stem Cells Ameliorate Carbon Tetrachloride-Induced Liver Cirrhosis in Mouse
- (2011) DingGuo Zhang et al. PLoS One
- Mesenchymal stem cells impair in vivo T-cell priming by dendritic cells
- (2011) S. Chiesa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transforming Growth Factor β-Mediated Sox10 Suppression Controls Mesenchymal Progenitor Generation in Neural Crest Stem Cells
- (2011) Nessy John et al. STEM CELLS
- Human Mesenchymal Stem Cells Reprogram Adult Cardiomyocytes Toward a Progenitor-Like State Through Partial Cell Fusion and Mitochondria Transfer
- (2011) Adrien Acquistapace et al. STEM CELLS
- Concise Review: Mesenchymal Stem Cell Tumor-Homing: Detection Methods in Disease Model Systems
- (2011) Michaela R. Reagan et al. STEM CELLS
- Heparan Sulfate Enhances the Self-Renewal and Therapeutic Potential of Mesenchymal Stem Cells from Human Adult Bone Marrow
- (2011) Torben Helledie et al. STEM CELLS AND DEVELOPMENT
- Organotins Are Potent Activators of PPARγ and Adipocyte Differentiation in Bone Marrow Multipotent Mesenchymal Stromal Cells
- (2011) Susan C. Yanik et al. TOXICOLOGICAL SCIENCES
- Hepatogenic differentiation of mesenchymal stem cells induced by insulin like growth factor-I
- (2011) Maryam Ayatollahi World Journal of Stem Cells
- Human CD133-derived bone marrow stromal cells establish ectopic hematopoietic microenvironments in immunodeficient mice
- (2010) Benjamin Bakondi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- No contribution of umbilical cord mesenchymal stromal cells to capillarization and venularization of hepatic sinusoids accompanied by hepatic differentiation in carbon tetrachloride-induced mouse liver fibrosis
- (2010) Hongying Ren et al. CYTOTHERAPY
- Defining the risks of mesenchymal stromal cell therapy
- (2010) Darwin J. Prockop et al. CYTOTHERAPY
- Mesenchymal stem cells as therapeutic tools and gene carriers in liver fibrosis and hepatocellular carcinoma
- (2010) J B Aquino et al. GENE THERAPY
- Intracellular reactive oxygen species are required for directional migration of resident and bone marrow-derived hepatic pro-fibrogenic cells
- (2010) Erica Novo et al. JOURNAL OF HEPATOLOGY
- Enhanced actions of insulin-like growth factor-I and interferon-α co-administration in experimental cirrhosis
- (2010) Federico Tutau et al. LIVER INTERNATIONAL
- Prenatal Exposure to the Environmental Obesogen Tributyltin Predisposes Multipotent Stem Cells to Become Adipocytes
- (2010) Séverine Kirchner et al. MOLECULAR ENDOCRINOLOGY
- Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
- (2010) Simón Méndez-Ferrer et al. NATURE
- Unique multipotent cells in adult human mesenchymal cell populations
- (2010) Y. Kuroda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Differentiation of Bone Marrow-derived Mesenchymal Stem Cells into Hepatocyte-like Cells on Nanofibers and Their Transplantation into a Carbon Tetrachloride-Induced Liver Fibrosis Model
- (2010) Abbas Piryaei et al. Stem Cell Reviews and Reports
- Development of mesenchymal stem cells partially originate from the neural crest
- (2009) Satoru Morikawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Clinical-grade production of human mesenchymal stromal cells: occurrence of aneuploidy without transformation
- (2009) K. Tarte et al. BLOOD
- Schwann Cell Precursors from Nerve Innervation Are a Cellular Origin of Melanocytes in Skin
- (2009) Igor Adameyko et al. CELL
- Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats
- (2009) M. B. Herrera et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Mesenchymal Stem Cell-Derived Microvesicles Protect Against Acute Tubular Injury
- (2009) S. Bruno et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- CD133 Identifies a Human Bone Marrow Stem/Progenitor Cell Sub-population With a Repertoire of Secreted Factors That Protect Against Stroke
- (2009) Benjamin Bakondi et al. MOLECULAR THERAPY
- A new role of substance P as an injury-inducible messenger for mobilization of CD29+ stromal-like cells
- (2009) Hyun Sook Hong et al. NATURE MEDICINE
- Stem Cell Therapy for Liver Disease: Parameters Governing the Success of Using Bone Marrow Mesenchymal Stem Cells
- (2008) Tom K. Kuo et al. GASTROENTEROLOGY
- Hepatocyte differentiation of mesenchymal stem cells from human adipose tissue in vitro promotes hepatic integration in vivo
- (2008) H Aurich et al. GUT
- Activation of hepatic stellate cells is associated with cytokine expression in thioacetamide-induced hepatic fibrosis in mice
- (2008) Rebeca Salguero Palacios et al. LABORATORY INVESTIGATION
- Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation
- (2008) Clas B. Johansson et al. NATURE CELL BIOLOGY
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