Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy

A Stochastic Step Model of Replicative Senescence Explains ROS Production Rate in Ageing Cell Populations

(2012) Conor Lawless et al.   PLoS One

Culture of human mesenchymal stem cells at low oxygen tension improves growth and genetic stability by activating glycolysis

(2011) J C Estrada et al.   CELL DEATH AND DIFFERENTIATION

Large-Scale Analysis Reveals Acquisition of Lineage-Specific Chromosomal Aberrations in Human Adult Stem Cells

(2011) Uri Ben-David et al.   Cell Stem Cell

Dynamic Changes in the Copy Number of Pluripotency and Cell Proliferation Genes in Human ESCs and iPSCs during Reprogramming and Time in Culture

(2011) Louise C. Laurent et al.   Cell Stem Cell

Importance of serum source for the in vitro replicative senescence of human bone marrow derived mesenchymal stem cells

(2011) Shivali Duggal et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria

(2011) Nilesh K. Sharma et al.   NUCLEIC ACIDS RESEARCH

Normal Human Pluripotent Stem Cell Lines Exhibit Pervasive Mosaic Aneuploidy

(2011) Suzanne E. Peterson et al.   PLoS One

Spontaneous Malignant Transformation of Human Mesenchymal Stem Cells Reflects Cross-Contamination: Putting the Research Field on Track - Letter

(2010) A. Torsvik et al.   CANCER RESEARCH

hTERT Overexpression Alleviates Intracellular ROS Production, Improves Mitochondrial Function, and Inhibits ROS-Mediated Apoptosis in Cancer Cells

(2010) I. R. Indran et al.   CANCER RESEARCH

Pitfalls in spontaneous in vitro transformation of human mesenchymal stem cells

(2010) S. Garcia et al.   EXPERIMENTAL CELL RESEARCH

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

Artefactual effects of oxygen on cell culture models of cellular senescence and stem cell biology

(2010) Olivier Toussaint et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inflammatory networks during cellular senescence: causes and consequences

(2010) Adam Freund et al.   TRENDS IN MOLECULAR MEDICINE

Mitochondrial Telomerase Reverse Transcriptase Binds to and Protects Mitochondrial DNA and Function From Damage

(2009) Judith Haendeler et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA

(2009) Yoshiko Maida et al.   NATURE

Aging and Replicative Senescence Have Related Effects on Human Stem and Progenitor Cells

(2009) Wolfgang Wagner et al.   PLoS One

Chromosome 7 and 19 Trisomy in Cultured Human Neural Progenitor Cells

(2009) Dhruv Sareen et al.   PLoS One

Long-term In vitro Expansion Alters the Biology of Adult Mesenchymal Stem Cells

(2008) R. Izadpanah et al.   CANCER RESEARCH

Introducing a single-cell-derived human mesenchymal stem cell line expressing hTERT after lentiviral gene transfer

(2008) Wolfgang Böcker et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Recurrent chromosomal abnormalities in human embryonic stem cells

(2008) Claudia Spits et al.   NATURE BIOTECHNOLOGY

TERT Promotes Epithelial Proliferation through Transcriptional Control of a Myc- and Wnt-Related Developmental Program

(2008) Jinkuk Choi et al.   PLoS Genetics

Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process

(2008) Wolfgang Wagner et al.   PLoS One

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY