Leukotriene B4–mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes

Molecular determinants of sterile inflammation

(2014) Hajime Kono et al.   CURRENT OPINION IN IMMUNOLOGY

Macrophages, Immunity, and Metabolic Disease

(2014) Joanne C. McNelis et al.   IMMUNITY

Leukotriene B4 Enhances the Generation of Proinflammatory MicroRNAs To Promote MyD88-Dependent Macrophage Activation

(2014) Z. Wang et al.   JOURNAL OF IMMUNOLOGY

PPAR- /IL-10 Axis Inhibits MyD88 Expression and Ameliorates Murine Polymicrobial Sepsis

(2014) A. E. Ferreira et al.   JOURNAL OF IMMUNOLOGY

Processes of Sterile Inflammation

(2013) H. Shen et al.   JOURNAL OF IMMUNOLOGY

Gut Microbiota, Low-grade Inflammation, and Metabolic Syndrome

(2013) Benoit Chassaing et al.   TOXICOLOGIC PATHOLOGY

Prostaglandin E2 restrains macrophage maturation via E prostanoid receptor 2/protein kinase A signaling

(2012) Z. Zaslona et al.   BLOOD

Anti-Inflammatory Therapy in Type 1 Diabetes

(2012) Bernd Baumann et al.   Current Diabetes Reports

 1-Acid Glycoprotein Decreases Neutrophil Migration and Increases Susceptibility to Sepsis in Diabetic Mice

(2012) F. Spiller et al.   DIABETES

The broad clinical phenotype of Type 1 diabetes at presentation

(2012) S. R. Merger et al.   DIABETIC MEDICINE

Insulin Treatment Directly Restores Neutrophil Phagocytosis and Bactericidal Activity in Diabetic Mice and Thereby Improves Surgical Site Staphylococcus aureus Infection

(2012) Hidekazu Yano et al.   INFECTION AND IMMUNITY

Macrophage Dectin-1 Expression Is Controlled by Leukotriene B4 via a GM-CSF/PU.1 Axis

(2012) C. H. Serezani et al.   JOURNAL OF IMMUNOLOGY

Regulation of alveolar macrophage p40phox: hierarchy of activating kinases and their inhibition by PGE2

(2012) Emilie Bourdonnay et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Danger Signals Activating the Immune Response after Trauma

(2012) Stefanie Hirsiger et al.   MEDIATORS OF INFLAMMATION

Inflammasomes: far beyond inflammation

(2012) Jorge Henao-Mejia et al.   NATURE IMMUNOLOGY

Mechanisms of joint damage in gout: evidence from cellular and imaging studies

(2012) Fiona M. McQueen et al.   Nature Reviews Rheumatology

Sepsis-Induced Acute Lung Injury (ALI) Is Milder in Diabetic Rats and Correlates with Impaired NFkB Activation

(2012) Luciano R. Filgueiras et al.   PLoS One

Molecular Phenotyping of Immune Cells from Young NOD Mice Reveals Abnormal Metabolic Pathways in the Early Induction Phase of Autoimmune Diabetes

(2012) Jian Wu et al.   PLoS One

The inflammatory response in sepsis

(2012) Markus Bosmann et al.   TRENDS IN IMMUNOLOGY

NF-κB, Inflammation, and Metabolic Disease

(2011) Rebecca G. Baker et al.   Cell Metabolism

Leukotrienes Target F-actin/Cofilin-1 to Enhance Alveolar Macrophage Anti-fungal Activity

(2011) Mariana Morato-Marques et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Protein Kinase A Anchoring Proteins Direct Prostaglandin E2Modulation of Toll-like Receptor Signaling in Alveolar Macrophages

(2011) Sang-Hoon Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leukotriene B4 amplifies NF-κB activation in mouse macrophages by reducing SOCS1 inhibition of MyD88 expression

(2011) Carlos H. Serezani et al.   JOURNAL OF CLINICAL INVESTIGATION

Deficiency of the Leukotriene B4 Receptor, BLT-1, Protects against Systemic Insulin Resistance in Diet-Induced Obesity

(2011) M. Spite et al.   JOURNAL OF IMMUNOLOGY

S961, an insulin receptor antagonist causes hyperinsulinemia, insulin-resistance and depletion of energy stores in rats

(2010) Ajit Vikram et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The leukotriene B4 receptor, BLT1, is required for the induction of experimental autoimmune encephalomyelitis

(2010) Yasuyuki Kihara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of oxidative stress and inflammation by glycaemic control: evidence for reversible activation of the 5-lipoxygenase pathway in type 1, but not in type 2 diabetes

(2010) R. Boizel et al.   DIABETOLOGIA

The Systemic Pro-Inflammatory Response in Sepsis

(2010) Hanna Katrien de Jong et al.   Journal of Innate Immunity

Impaired phagocytosis by alveolar macrophages from diabetic rats is related to the deficient coupling of LTs to the FcγR signaling cascade

(2010) Matheus Ferracini et al.   MOLECULAR IMMUNOLOGY

NEUTROPHIL PARALYSIS IN SEPSIS

(2010) José C. Alves-Filho et al.   SHOCK

Mechanisms of inflammation in gout

(2010) Nathalie Busso et al.   ARTHRITIS RESEARCH & THERAPY

Fc RI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions

(2009) C. H. Serezani et al.   BLOOD

Sepsis as a model of SIRS

(2009) Madhav Bhatia   Frontiers in Bioscience-Landmark

The role of Toll-like receptors in chronic inflammation

(2009) Stefan K. Drexler et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cyclic AMP

(2008) Carlos H. Serezani et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A novel high-affinity peptide antagonist to the insulin receptor

(2008) Lauge Schäffer et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

 -Cell Mass and Type 1 Diabetes: Going, Going, Gone?

(2008) E. Akirav et al.   DIABETES