Anti-Inflammatory Therapy in Type 1 Diabetes

Role of NF-κB in the pathogenesis of diabetes and its associated complications

(2014) Sandip Patel et al.   Pharmacological Reports

Lipoic acid – biological activity and therapeutic potential

(2014) Anna Gorąca et al.   Pharmacological Reports

Glycotoxin and Autoantibodies Are Additive Environmentally Determined Predictors of Type 1 Diabetes

(2012) Huriya Beyan et al.   DIABETES

Islet  -Cell Endoplasmic Reticulum Stress Precedes the Onset of Type 1 Diabetes in the Nonobese Diabetic Mouse Model

(2012) S. A. Tersey et al.   DIABETES

NF-κB function in B lymphocytes

(2012) Mary Kaileh et al.   IMMUNOLOGICAL REVIEWS

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

(2012) Ken T. Coppieters et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles

(2012) Benjamin P Fairfax et al.   NATURE GENETICS

Improved Preservation of Residual Beta Cell Function by Atorvastatin in Patients with Recent Onset Type 1 Diabetes and High CRP Levels (DIATOR Trial)

(2012) Alexander Strom et al.   PLoS One

The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines

(2012) Décio L. Eizirik et al.   PLoS Genetics

Protection from diabetes development by single-chain antibody-mediated delivery of a NF-κB inhibitor specifically to β-cells in vivo

(2011) Sandra Ueberberg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

NF-κB, Inflammation, and Metabolic Disease

(2011) Rebecca G. Baker et al.   Cell Metabolism

Effects of Flavonoids and other Polyphenols on Inflammation

(2011) R. González et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

High Pancreatic n-3 Fatty Acids Prevent STZ-Induced Diabetes in Fat-1 Mice: Inflammatory Pathway Inhibition

(2011) J. Bellenger et al.   DIABETES

Expression and Regulation of Chemokines in Murine and Human Type 1 Diabetes

(2011) S. A. Sarkar et al.   DIABETES

High-Dose Aspirin Is Required to Influence Plasma Fibrin Network Structure in Patients With Type 1 Diabetes

(2011) S. Tehrani et al.   DIABETES CARE

Effect of Sanguis draconis (a dragon's blood resin) on streptozotocin- and cytokine-induced β-cell damage, in vitro and in vivo

(2011) Chien-Ming Hu et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes

(2011) J. M. Forbes et al.   DIABETOLOGIA

Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes

(2011) S.-M. Lee et al.   DIABETOLOGIA

The Ca2+-dependent Phosphatase Calcineurin Controls the Formation of the Carma1-Bcl10-Malt1 Complex during T Cell Receptor-induced NF-κB Activation

(2011) Lysann Palkowitsch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atorvastatin upregulates regulatory T cells and reduces clinical disease activity in patients with rheumatoid arthritis

(2011) Ting-Ting Tang et al.   JOURNAL OF LIPID RESEARCH

Understanding type 1 diabetes through genetics: advances and prospects

(2011) Constantin Polychronakos et al.   NATURE REVIEWS GENETICS

Residual Beta Cell Function in Newly Diagnosed Type 1 Diabetes after Treatment with Atorvastatin: The Randomized DIATOR Trial

(2011) Stephan Martin et al.   PLoS One

Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and  -cell apoptosis

(2011) L. A. Berchtold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The microRNA-21-PDCD4 axis prevents type 1 diabetes by blocking pancreatic   cell death

(2011) Q. Ruan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

B cell-directed therapies in type 1 diabetes

(2011) Eliana Mariño et al.   TRENDS IN IMMUNOLOGY

NF-κB signaling pathways regulated by CARMA family of scaffold proteins

(2010) Marzenna Blonska et al.   CELL RESEARCH

Sulfuretin protects against cytokine-induced β-cell damage and prevents streptozotocin-induced diabetes

(2010) Mi-Young Song et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

The unique hypusine modification of eIF5A promotes islet β cell inflammation and dysfunction in mice

(2010) Bernhard Maier et al.   JOURNAL OF CLINICAL INVESTIGATION

Blockade of interleukin 1 in type 1 diabetes mellitus

(2010) Thomas Mandrup-Poulsen et al.   Nature Reviews Endocrinology

Immunopathology of the human pancreas in type-I diabetes

(2010) Sarah J. Richardson et al.   Seminars in Immunopathology

Atorvastatin has antithrombotic effects in patients with type 1 diabetes and dyslipidemia

(2010) Sara Tehrani et al.   THROMBOSIS RESEARCH

Antigen Receptor Signaling to NF- B via CARMA1, BCL10, and MALT1

(2010) M. Thome et al.   Cold Spring Harbor Perspectives in Biology

Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications

(2009) A. Bierhaus et al.   DIABETOLOGIA

Fermented ginseng protects streptozotocin-induced damage in rat pancreas by inhibiting nuclear factor-κB

(2009) Hai Dan Yuan et al.   PHYTOTHERAPY RESEARCH

Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes

(2009) S. Nejentsev et al.   SCIENCE

The IκB kinase – a bridge between inflammation and cancer

(2008) Michael Karin   CELL RESEARCH

Analysis of islet inflammation in human type 1 diabetes

(2008) A. Willcox et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY